Novel, provable algorithms for efficient ensemble-based computational protein design and their application to the redesign of the c-Raf-RBD:KRas protein-protein interface. by Anna U Lowegard, Marcel S Frenkel, Graham T Holt, Jonathan D Jou, Adegoke A Ojewole, Bruce R Donald

Get full text

Chiral evasion and stereospecific antifolate resistance in Staphylococcus aureus. by Siyu Wang, Stephanie M Reeve, Graham T Holt, Adegoke A Ojewole, Marcel S Frenkel, Pablo Gainza, Santosh Keshipeddy, Vance G Fowler, Dennis L Wright, Bruce R Donald

Get full text

A Low Affinity GCaMP3 Variant (GCaMPer) for Imaging the Endoplasmic Reticulum Calcium Store. by Mark J Henderson, Heather A Baldwin, Christopher A Werley, Stefano Boccardo, Leslie R Whitaker, Xiaokang Yan, Graham T Holt, Eric R Schreiter, Loren L Looger, Adam E Cohen, Douglas S Kim, Brandon K Harvey

Get full text

Improved HIV-1 neutralization breadth and potency of V2-apex antibodies by in silico design by Graham T. Holt, Jason Gorman, Siyu Wang, Anna U. Lowegard, Baoshan Zhang, Tracy Liu, Bob C. Lin, Mark K. Louder, Marcel S. Frenkel, Krisha McKee, Sijy O’Dell, Reda Rawi, Chen-Hsiang Shen, Nicole A. Doria-Rose, Peter D. Kwong, Bruce R. Donald

Get full text

Sensitive red protein calcium indicators for imaging neural activity by Hod Dana, Boaz Mohar, Yi Sun, Sujatha Narayan, Andrew Gordus, Jeremy P Hasseman, Getahun Tsegaye, Graham T Holt, Amy Hu, Deepika Walpita, Ronak Patel, John J Macklin, Cornelia I Bargmann, Misha B Ahrens, Eric R Schreiter, Vivek Jayaraman, Loren L Looger, Karel Svoboda, Douglas S Kim

Get full text