The identification and analysis of molecular biomarkers in the p53 tumour suppressor pathway that affect cancer progression in humans by Grawenda, A, Anna M Grawenda

TGF-β targets the hippo pathway scaffold RASSF1A to facilitate YAP/SMAD2 nuclear translocation by Pefani, E, Pankova, D, Abraham, A, Grawenda, A, Vlahov, N, Scrace, S, O'Neill, E

A RASSF1A polymorphism restricts p53/p73 activation and associates with poor survival and accelerated age of onset of soft tissue sarcoma. by Yee, K, Grochola, L, Hamilton, G, Grawenda, A, Bond, E, Taubert, H, Wurl, P, Bond, G, O'Neill, E

RASSF1A-LATS1 signalling stabilizes replication forks by restricting CDK2-mediated phosphorylation of BRCA2. by Pefani, D, Latusek, R, Pires, I, Grawenda, A, Yee, K, Hamilton, G, van der Weyden, L, Esashi, F, Hammond, E, O'Neill, E

Alternate splicing of the p53 inhibitor HDMX offers a superior prognostic biomarker than p53 mutation in human cancer. by Lenos, K, Grawenda, A, Lodder, K, Kuijjer, M, Teunisse, A, Repapi, E, Grochola, L, Bartel, F, Hogendoorn, P, Wuerl, P, Taubert, H, Cleton-Jansen, A, Bond, G, Jochemsen, A

Polymorphisms in the p53 pathway are enriched in cancer susceptibility loci and share characteristics with somatic pathway mutations by Stracquadanio, G, Wallace, M, Grawenda, A, Zhang, P, Hewitt, J, Zeron-Medina, J, Castro-Giner, F, Tomlinson, I, Goding, C, Cygan, K, Fairbrother, W, Thomas, L, Saetrom, P, Gemignani, F, Landi, S, Schuster-Boeckler, B, Bell, D, Bond, G

The importance of p53 pathway genetics in inherited and somatic cancer genomes by Stracquadanio, G, Wang, X, Wallace, M, Grawenda, A, Zhang, P, Hewitt, J, Zeron-Medina, J, Castro-Giner, F, Tomlinson, I, Goding, C, Cygan, K, Fairbrother, W, Thomas, L, Saetrom, P, Gemignani, F, Landi, S, Schuster-Boeckler, B, Bell, D, Bond, G

RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated differentiation via p73. by Papaspyropoulos, A, Bradley, L, Thapa, A, Leung, C, Toskas, K, Koennig, D, Pefani, D, Raso, C, Grou, C, Hamilton, G, Vlahov, N, Grawenda, A, Haider, S, Chauhan, J, Buti, L, Kanapin, A, Lu, X, Buffa, F, Dianov, G, von Kriegsheim, A, Matallanas, D, Samsonova, A, Zernicka-Goetz, M, O'Neill, E