Showing 1 - 20 results of 36 for search 'Gray, Nathanael S.', query time: 0.03s
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Chaperones as thermodynamic sensors of drug-target interactions reveal kinase inhibitor specificities in living cells by Taipale, Mikko, Krykbaeva, Irina, Whitesell, Luke, Santagata, Sandro, Zhang, Jianming, Liu, Qingsong, Gray, Nathanael S., Lindquist, Susan
Published 2014
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Discovery of 9-(6-aminopyridin-3-yl)-1-(3- (trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one (Torin2) as a potent, selective and orally available mTOR inhibitor for treat... by Liu, Qingsong, Wang, Jinhua, Kang, Seong A., Thoreen, Carson C., Hur, Wooyoung, Ahmed, Tausif, Gray, Nathanael S., Sabatini, David
Published 2012
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DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival by Peterson, Timothy R., Laplante, Mathieu, Thoreen, Carson C., Sancak, Yasemin, Kang, Seong A., Kuehl, W. Michael, Gray, Nathanael S., Sabatini, David M.
Published 2015
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Selective ATP-Competitive Inhibitors of TOR Suppress Rapamycin-Insensitive Function of TORC2 in S. cerevisiae by Liu, Qingsong, Ren, Tao, Fresques, Tara, Oppliger, Wolfgang, Niles, Brad J., Hur, Wooyoung, Hall, Michael N., Powers, Ted, Gray, Nathanael S., Sabatini, David
Published 2015
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Discovery of 1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a Highly Potent, Selective Mammalian Target of Rapa... by Liu, Qingsong, Chang, Jae Won, Wang, Jinhua, Kang, Seong A., Thoreen, Carson C., Markhard, Andrew L., Hur, Wooyoung, Zhang, Jianming, Sim, Taebo, Gray, Nathanael S., Sabatini, David
Published 2014
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Inhibitor-Sensitive FGFR1 Amplification in Human Non-Small Cell Lung Cancer by Dutt, Amit, Ramos, Alex H., Hammerman, Peter S., Mermel, Craig H., Cho, Jeonghee, Sharifnia, Tanaz, Chande, Ajit, Tanaka, Kumiko Elisa, Stransky, Nicolas, Greulich, Heidi, Gray, Nathanael S., Meyerson, Matthew L.
Published 2011
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mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin by Kang, Seong A., Cervantes, Christopher L., Lim, Daniel Cham-Chin, Ottina, Kathleen, Lou, Hua Jane, Gray, Nathanael S., Turk, Benjamin E., Pacold, Michael Edward, Yaffe, Michael B, Sabatini, David
Published 2014
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mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin by Cervantes, Christopher L., Lim, Daniel Cham-Chin, Kang, Seong A., Pacold, Michael E., Lou, Hua Jane, Ottina, Kathleen, Gray, Nathanael S., Turk, Benjamin E., Yaffe, Michael B, Sabatini, David
Published 2014
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Activation of the p53 Transcriptional Program Sensitizes Cancer Cells to Cdk7 Inhibitors by Kalan, Sampada, Amat, Ramon, Schachter, Miriam Merzel, Kwiatkowski, Nicholas, Abraham, Brian J., Liang, Yanke, Zhang, Tinghu, Olson, Calla M., Larochelle, Stéphane, Gray, Nathanael S., Fisher, Robert P., Young, Richard A.
Published 2018
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The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling by Rameseder, J., Zhang, Y., Ottina, Kathleen, Lim, D., Choi, Y., Gray, Nathanael S., Yaffe, M. B., Marto, Jarrod A., Hsu, Peggy P., Kang, Seong A., Peterson, Timothy R., Sabatini, David M.
Published 2013
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High MITF Expression Is Associated with Super-Enhancers and Suppressed by CDK7 Inhibition in Melanoma by Eliades, Philip, Abraham, Brian J., Ji, Zhenyu, Christensen, Camilla L., Kwiatkowski, Nicholas, Kumar, Raj, Njauw, Ching Ni, Taylor, Michael, Miao, Benchun, Zhang, Tinghu, Wong, Kwok-Kin, Gray, Nathanael S., Tsao, Hensin, Young, Richard A., Miller, David M., III
Published 2019
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CDK7-Dependent Transcriptional Addiction in Triple-Negative Breast Cancer by Wang, Yubao, Zhang, Tinghu, Kwiatkowski, Nicholas, Abraham, Brian J., Lee, Tong Ihn, Xie, Shaozhen, Yuzugullu, Haluk, Von, Thanh, Li, Heyuan, Lin, Ziao, Stover, Daniel G., Lim, Elgene, Wang, Zhigang C., Iglehart, J. Dirk, Gray, Nathanael S., Zhao, Jean J., Young, Richard A.
Published 2017
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CDK7 Inhibition Suppresses Super-Enhancer-Linked Oncogenic Transcription in MYCN-Driven Cancer by Chipumuro, Edmond, Marco, Eugenio, Christensen, Camilla L., Zhang, Tinghu, Hatheway, Clark M., Sharma, Bandana, Yeung, Caleb, Altabef, Abigail, Perez-Atayde, Antonio, Wong, Kwok-Kin, Yuan, Guo-Cheng, Gray, Nathanael S., George, Rani E., Kwiatkowski, Nick, Abraham, Brian Joseph, Young, Richard A.
Published 2017
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Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation by Olson, Calla M, Jiang, Baishan, Erb, Michael A, Liang, Yanke, Doctor, Zainab M, Zhang, Zinan, Zhang, Tinghu, Kwiatkowski, Nicholas, Boukhali, Myriam, Green, Jennifer L, Haas, Wilhelm, Nomanbhoy, Tyzoon, Fischer, Eric S, Bradner, James E, Winter, Georg E, Gray, Nathanael S, Young, Richard A.
Published 2018
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EWS/FLI Confers Tumor Cell Synthetic Lethality to CDK12 Inhibition in Ewing Sarcoma by Iniguez, Amanda Balboni, Stolte, Björn, Wang, Emily Jue, Conway, Amy Saur, Alexe, Gabriela, Dharia, Neekesh V., Kwiatkowski, Nicholas, Zhang, Tinghu, Abraham, Brian J., Mora, Jaume, Kalev, Peter, Leggett, Alan, Chowdhury, Dipanjan, Benes, Cyril H., Gray, Nathanael S., Stegmaier, Kimberly, Young, Richard A.
Published 2019
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Studies of TAK1-centered polypharmacology with novel covalent TAK1 inhibitors by Tan, Li, Gurbani, Deepak, Weisberg, Ellen L., Jones II, Douglas S., Rao, Suman, Singer, William D., Bernard, Faviola M., Mowafy, Samar, Jenney, Annie, Du, Guangyan, Nonami, Atsushi, Griffin, James D., Lauffenburger, Douglas A, Westover, Kenneth D., Sorger, Peter K., Gray, Nathanael S.
Published 2021
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Targeting transcription in heart failure via CDK7/12/13 inhibition by Hsu, Austin, Duan, Qiming, Day, Daniel S, Luo, Xin, McMahon, Sarah, Huang, Yu, Feldman, Zachary B, Jiang, Zhen, Zhang, Tinghu, Liang, Yanke, Alexanian, Michael, Padmanabhan, Arun, Brown, Jonathan D, Lin, Charles Y, Gray, Nathanael S, Young, Richard A, Bruneau, Benoit G, Haldar, Saptarsi M
Published 2023
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YY1 Is a Structural Regulator of Enhancer-Promoter Loops by Sigova, Alla A., Hannett, Nancy M., Day, Daniel S., Abraham, Brian J., Cohen, Malkiel A., Nabet, Behnam, Buckley, Dennis L., Guo, Yang Eric, Hnisz, Denes, Bradner, James E., Gray, Nathanael S., Weintraub, Abraham Selby, Li, Charles Han, Zamudio Montes de Oca, Alicia, Jaenisch, Rudolf, Young, Richard A.
Published 2018
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