Tumor Microenvironment Metabolism: A New Checkpoint for Anti-Tumor Immunity by Nicole E. Scharping, Greg M. Delgoffe

Get full text

Fighting in a wasteland: deleterious metabolites and antitumor immunity by McLane J. Watson, Greg M. Delgoffe

Get full text

Treatment with oncolytic vaccinia virus infects tumor-infiltrating regulatory and exhausted T cells by Greg M Delgoffe, Kristin DePeaux, William G Gunn, Dayana B Rivadeneira

Get full text

89723 CD105-targeted CAR T cells for the treatment of acute myeloid leukemia by Konstantinos Lontos, Yiyang Wang, Andrew Frisch, Mason Colbert, Jason Lohmueller, Greg M. Delgoffe

Get full text

Tumor hypoxia is associated with resistance to PD-1 blockade in squamous cell carcinoma of the head and neck by Greg M Delgoffe, Kristin DePeaux, Angen Liu, Dan P Zandberg, Ashley V Menk, Maria Velez, Daniel Normolle

Get full text

Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells by Stephanie Downs-Canner, Sara Berkey, Greg M. Delgoffe, Robert P. Edwards, Tyler Curiel, Kunle Odunsi, David L. Bartlett, Nataša Obermajer

Get full text

IL-23 and IL-1β Drive Human Th17 Cell Differentiation and Metabolic Reprogramming in Absence of CD28 Costimulation by Shankar Revu, Jing Wu, Matthew Henkel, Natalie Rittenhouse, Ashley Menk, Greg M. Delgoffe, Amanda C. Poholek, Mandy J. McGeachy

Get full text

Fully murine CD105-targeted CAR-T cells provide an immunocompetent model for CAR-T cell biology by Konstantinos Lontos, Yiyang Wang, Mason Colbert, Alok Kumar, Supriya Joshi, Mary Philbin, Yupeng Wang, Andrew Frisch, Jason Lohmueller, Dayana B. Rivadeneira, Greg M. Delgoffe

Get full text

Antiviral epithelial-macrophage crosstalk permits secondary bacterial infections by Sidney Lane, Tristan L. A. White, Erin E. Walsh, Richard T. Cattley, Rachel Cumberland, William F. Hawse, Greg M. Delgoffe, Stephen F. Badylak, Jennifer M. Bomberger

Get full text

Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions by Ashley V. Menk, Nicole E. Scharping, Rebecca S. Moreci, Xue Zeng, Cliff Guy, Sonia Salvatore, Heekyong Bae, Jianxin Xie, Howard A. Young, Stacy Gelhaus Wendell, Greg M. Delgoffe

Get full text

The schedule of ATR inhibitor AZD6738 can potentiate or abolish antitumor immune responses to radiotherapy by Frank P. Vendetti, Pinakin Pandya, David A. Clump, Sandra Schamus-Haynes, Meysam Tavakoli, Maria diMayorca, Naveed M. Islam, Jina Chang, Greg M. Delgoffe, Jan H. Beumer, Christopher J. Bakkenist

Get full text

Metabolic reprogramming via an engineered PGC-1α improves human chimeric antigen receptor T-cell therapy against solid tumors by Benjamin Boyerinas, Greg M Delgoffe, Yupeng Wang, Alok Kumar, Ashley V Menk, Konstantinos Lontos, Yiyang Wang, Jason Lohmueller, Supriya K Joshi, Andrew T Frisch, McLane J Watson, Rachel Cumberland, Esteban Carrizosa

Get full text

Lymphocyte Activation Gene-3 Maintains Mitochondrial and Metabolic Quiescence in Naive CD4+ T Cells by Dana M. Previte, Christina P. Martins, Erin C. O’Connor, Meghan L. Marre, Gina M. Coudriet, Noah W. Beck, Ashley V. Menk, Rebecca H. Wright, Hubert M. Tse, Greg M. Delgoffe, Jon D. Piganelli

Get full text

Interferon signaling drives epithelial metabolic reprogramming to promote secondary bacterial infection by Grace P. Carreno-Florez, Brian R. Kocak, Matthew R. Hendricks, Jeffrey A. Melvin, Katrina B. Mar, Jessica Kosanovich, Rachel L. Cumberland, Greg M. Delgoffe, Sruti Shiva, Kerry M. Empey, John W. Schoggins, Jennifer M. Bomberger

Get full text

Interferon signaling drives epithelial metabolic reprogramming to promote secondary bacterial infection. by Grace P Carreno-Florez, Brian R Kocak, Matthew R Hendricks, Jeffrey A Melvin, Katrina B Mar, Jessica Kosanovich, Rachel L Cumberland, Greg M Delgoffe, Sruti Shiva, Kerry M Empey, John W Schoggins, Jennifer M Bomberger

Get full text

Metformin is associated with improved clinical outcomes in patients with melanoma: a retrospective, multi-institutional study by Ryan C. Augustin, Ryan C. Augustin, Ziyu Huang, Fei Ding, Shuyan Zhai, Jennifer McArdle, Anthony Santisi, Michael Davis, Cindy Sander, Diwakar Davar, John M. Kirkwood, John M. Kirkwood, Greg M. Delgoffe, Allison Betof Warner, Yana G. Najjar, Yana G. Najjar

Get full text

Perspectives in immunotherapy: meeting report from the “Immunotherapy Bridge 2018” (28–29 November, 2018, Naples, Italy) by Paolo A. Ascierto, Carlo Bifulco, Luigi Buonaguro, Leisha A. Emens, Robert L. Ferris, Bernard A. Fox, Greg M. Delgoffe, Jérôme Galon, Cesare Gridelli, Marco Merlano, Paul Nathan, Kunle Odunsi, Hideho Okada, Chrystal M. Paulos, Sandro Pignata, Kurt A. Schalper, Stefani Spranger, Giampaolo Tortora, Hassane Zarour, Lisa H. Butterfield, Igor Puzanov

Get full text

Excess Dietary Sugar Alters Colonocyte Metabolism and Impairs the Proliferative Response to DamageSummary by Ansen H.P. Burr, Junyi Ji, Kadir Ozler, Heather L. Mentrup, Onur Eskiocak, Brian Yueh, Rachel Cumberland, Ashley V. Menk, Natalie Rittenhouse, Chris W. Marshall, Pailin Chiaranunt, Xiaoyi Zhang, Lauren Mullinax, Abigail Overacre-Delgoffe, Vaughn S. Cooper, Amanda C. Poholek, Greg M. Delgoffe, Kevin P. Mollen, Semir Beyaz, Timothy W. Hand

Get full text