1202 In vivo engineering of CAR T cells using a novel targeted LNP-mRNA technology by Yan Zhang, Michael Peel, Adrian Bot, Brittany Ross, Duy Nguyen, Michelle Nguyen, Theresa Hunter, Gregor Adams, Barzan A Sadiq, Haig Aghajanian, Ferran Soldevila, Daiki Matsuda, Yanjie Bao, Stuart A Sievers, John Li, Josephine Nguyen, Claudia Fernandez, Yi Kuo, James Vestal, Matthew Butcher, Jeffrey Chen, Stanley Zhang, Makan Khoshnejad, Donald Jhung, Steve Tanis, Michael Rosenzweig, Priya Karmali