Minimally Modified HIV-1 Infection of Macaques: Development, Utility, and Limitations of Current Models av Manish Sharma, Mukta Nag, Gregory Q. Del Prete

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Tissue-Specific DNA Methylation Changes in CD8⁺ T Cells During Chronic Simian Immunodeficiency Virus Infection of Infant Rhesus Macaques av Mukta Nag, Jonathan E. Fogle, Santhoshan Pillay, Gregory Q. Del Prete, Kristina De Paris

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18 Expanded clones in SIV-infected macaques on antiretroviral therapy recapitulate key features of expanded clones in HIV infection: implications for evaluation of ‘HIV cure’ inter... av Xiaolin Wu, GregoryQ Del Prete, Andrea Ferris, AdrienneE Swanstrom, DavidW Wells, Shuang Guo, Stephen Hughes, JeffreyD Lifson

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Transient viral replication during analytical treatment interruptions in SIV infected macaques can alter the rebound-competent viral reservoir. av Taina T Immonen, Christine M Fennessey, Leslie Lipkey, Abigail Thorpe, Gregory Q Del Prete, Jeffrey D Lifson, Miles P Davenport, Brandon F Keele

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No evidence for ongoing replication on ART in SIV-infected macaques av Taina T. Immonen, Christine M. Fennessey, Leslie Lipkey, Laura Newman, Agatha Macairan, Marjorie Bosche, Nora Waltz, Gregory Q. Del Prete, Jeffrey D. Lifson, Brandon F. Keele

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Clonal expansion of SIV-infected cells in macaques on antiretroviral therapy is similar to that of HIV-infected cells in humans. av Andrea L Ferris, David W Wells, Shuang Guo, Gregory Q Del Prete, Adrienne E Swanstrom, John M Coffin, Xiaolin Wu, Jeffrey D Lifson, Stephen H Hughes

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Tracking the luminal exposure and lymphatic drainage pathways of intravaginal and intrarectal inocula used in nonhuman primate models of HIV transmission. av Jeremy Smedley, Baris Turkbey, Marcelino L Bernardo, Gregory Q Del Prete, Jacob D Estes, Gary L Griffiths, Hisataka Kobayashi, Peter L Choyke, Jeffrey D Lifson, Brandon F Keele

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Timing of initiation of anti-retroviral therapy predicts post-treatment control of SIV replication. av Mykola Pinkevych, Steffen S Docken, Afam A Okoye, Christine M Fennessey, Gregory Q Del Prete, Maria Pino, Justin L Harper, Michael R Betts, Mirko Paiardini, Brandon F Keele, Miles P Davenport

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AP-1/c-Fos supports SIV and HIV-1 latency in CD4 T cells infected in vivo av Viviana Cobos Jiménez, Aviva Geretz, Andrey Tokarev, Philip K. Ehrenberg, Selase Deletsu, Kawthar Machmach, Prakriti Mudvari, J. Natalie Howard, Amanda Zelkoski, Dominic Paquin-Proulx, Gregory Q. Del Prete, Caroline Subra, Eli A. Boritz, Alberto Bosque, Rasmi Thomas, Diane L. Bolton

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A single gp120 residue can affect HIV-1 tropism in macaques. av Gregory Q Del Prete, Brandon F Keele, Jeannine Fode, Keyur Thummar, Adrienne E Swanstrom, Anthony Rodriguez, Alice Raymond, Jacob D Estes, Celia C LaBranche, David C Montefiori, Vineet N KewalRamani, Jeffrey D Lifson, Paul D Bieniasz, Theodora Hatziioannou

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Genetically-barcoded SIV facilitates enumeration of rebound variants and estimation of reactivation rates in nonhuman primates following interruption of suppressive antiretroviral... av Christine M Fennessey, Mykola Pinkevych, Taina T Immonen, Arnold Reynaldi, Vanessa Venturi, Priyanka Nadella, Carolyn Reid, Laura Newman, Leslie Lipkey, Kelli Oswald, William J Bosche, Matthew T Trivett, Claes Ohlen, David E Ott, Jacob D Estes, Gregory Q Del Prete, Jeffrey D Lifson, Miles P Davenport, Brandon F Keele

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Long-acting lenacapavir protects macaques against intravenous challenge with simian-tropic HIVResearch in context av Adrienne E. Swanstrom, Robert J. Gorelick, Jorden L. Welker, Fabian Schmidt, Bing Lu, Kelly Wang, William Rowe, Matthew W. Breed, Kristin E. Killoran, Joshua A. Kramer, Duncan Donohue, James D. Roser, Paul D. Bieniasz, Theodora Hatziioannou, Cathi Pyle, James A. Thomas, Charles M. Trubey, Jim Zheng, Wade Blair, Stephen R. Yant, Jeffrey D. Lifson, Gregory Q. Del Prete

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Rational design and in vivo selection of SHIVs encoding transmitted/founder subtype C HIV-1 envelopes. av Sean P O'Brien, Adrienne E Swanstrom, Amarendra Pegu, Sung-Youl Ko, Taina T Immonen, Gregory Q Del Prete, Christine M Fennessey, Jason Gorman, Kathryn E Foulds, Stephen D Schmidt, Nicole Doria-Rose, Carolyn Williamson, Theodora Hatziioannou, Paul D Bieniasz, Hui Li, George M Shaw, John R Mascola, Richard A Koup, Peter D Kwong, Jeffrey D Lifson, Mario Roederer, Brandon F Keele

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HLA-C downregulation by HIV-1 adapts to host HLA genotype. av Nathaniel D Bachtel, Gisele Umviligihozo, Suzanne Pickering, Talia M Mota, Hua Liang, Gregory Q Del Prete, Pramita Chatterjee, Guinevere Q Lee, Rasmi Thomas, Mark A Brockman, Stuart Neil, Mary Carrington, Bosco Bwana, David R Bangsberg, Jeffrey N Martin, Esper G Kallas, Camila S Donini, Natalia B Cerqueira, Una T O'Doherty, Beatrice H Hahn, R Brad Jones, Zabrina L Brumme, Douglas F Nixon, Richard Apps

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Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy av Justin Harper, Susan P. Ribeiro, Chi Ngai Chan, Malika Aid, Claire Deleage, Luca Micci, Maria Pino, Barbara Cervasi, Gopalan Raghunathan, Eric Rimmer, Gulesi Ayanoglu, Guoxin Wu, Neeta Shenvi, Richard J.O. Barnard, Gregory Q. Del Prete, Kathleen Busman-Sahay, Guido Silvestri, Deanna A. Kulpa, Steven E. Bosinger, Kirk A. Easley, Bonnie J. Howell, Dan Gorman, Daria J. Hazuda, Jacob D. Estes, Rafick-Pierre Sekaly, Mirko Paiardini

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