Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure by Henry, A, Roselli, C, Lin, H, Sveinbjörnsson, G, Fatemifar, G, Hedman, AK, Wilk, JB, Morley, MP, Chaffin, MD, Helgadottir, A, Verweij, N, Dehghan, A, Almgren, P, Andersson, C, Aragam, KG, Ärnlöv, J, Backman, JD, Biggs, ML, Bloom, HL, Shah, S, Graciela E Delgado, Vilmantas Giedraitis, Brandimarto, J, Brown, MR, Buckbinder, L, Carey, DJ, Chasman, DI, Chen, X, Chen, X, Chung, J, Chutkow, W, Cook, JP, Denaxas, S, Doney, AS, Dörr, M, Dudley, SC, Dunn, ME, Engström, G, Esko, T, Felix, SB, Finan, C, Ford, I, Ghanbari, M, Ghasemi, S, Giulianini, F, Gottdiener, JS, Gross, S, Guðbjartsson, DF, Gutmann, R, Haggerty, CM

Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants by Aragam, KG, Jiang, T, Goel, A, Kanoni, S, Wolford, BN, Atri, DS, Weeks, EM, Wang, M, Hindy, G, Zhou, W, Grace, C, Roselli, C, Marston, NA, Kamanu, FK, Surakka, I, Venegas, LM, Sherliker, P, Koyama, S, Ishigaki, K, Åsvold, BO, Brown, MR, Brumpton, B, de Vries, PS, Giannakopoulou, O, Giardoglou, P, Gudbjartsson, DF, Güldener, U, Haider, SMI, Helgadottir, A, Ibrahim, M, Kastrati, A, Kessler, T, Kyriakou, T, Konopka, T, Li, L, Ma, L, Meitinger, T, Mucha, S, Munz, M, Murgia, F, Nielsen, JB, Nöthen, MM, Pang, S, Reinberger, T, Schnitzler, G, Smedley, D, Thorleifsson, G, von Scheidt, M, Ulirsch, JC, Biobank Japan, Hopewell, JC, Clarke, R, Watkins, H

Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes by Gusarova, V, O'Dushlaine, C, Teslovich, TM, Benotti, PN, Mirshahi, T, Gottesman, O, Van Hout, CV, Murray, MF, Mahajan, A, Nielsen, JB, Fritsche, L, Wulff, AB, Gudbjartsson, DF, Sjögren, M, Emdin, CA, Scott, RA, Lee, W-J, Small, A, Kwee, LC, Dwivedi, OP, Prasad, RB, Bruse, S, Lopez, AE, Penn, J, Marcketta, A, Leader, JB, Still, CD, Kirchner, HL, Mirshahi, UL, Wardeh, AH, Hartle, CM, Habegger, L, Fetterolf, SN, Tusie-Luna, T, Morris, AP, Holm, H, Steinthorsdottir, V, Sulem, P, Thorsteinsdottir, U, Rotter, JI, Chuang, L-M, Damrauer, S, Birtwell, D, Brummett, CM, Khera, AV, Natarajan, P, Orho-Melander, M, Flannick, J, Lotta, LA, Willer, CJ, Holmen, OL, Ritchie, MD, Ledbetter, DH, Murphy, AJ, Borecki, IB, Reid, JG, Overton, JD, Hansson, O, Groop, L, Shah, SH, Kraus, WE, Rader, DJ, Chen, Y-DI, Hveem, K, Wareham, NJ, Kathiresan, S, Melander, O, Stefansson, K, Nordestgaard, BG, Tybjærg-Hansen, A, Abecasis, GR, Altshuler, D, Florez, JC, Boehnke, M, McCarthy, MI, Yancopoulos, GD, Carey, DJ, Shuldiner, AR, Baras, A, Dewey, FE, Gromada, J

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use by Liu, M, Jiang, Y, Wedow, R, Li, Y, Brazel, DM, Chen, F, Datta, G, Davila-Velderrain, J, McGuire, D, Tian, C, Zhan, X, 23Andme Research Team, Hunt All-In Psychiatry, Choquet, H, Docherty, AR, Faul, JD, Foerster, JR, Fritsche, LG, Gabrielsen, ME, Gordon, SD, Haessler, J, Hottenga, J-J, Huang, H, Jang, S-K, Jansen, PR, Ling, Y, Mägi, R, Matoba, N, McMahon, G, Mulas, A, Orrù, V, Palviainen, T, Pandit, A, Reginsson, GW, Skogholt, AH, Smith, JA, Taylor, AE, Turman, C, Willemsen, G, Young, H, Young, KA, Zajac, GJM, Zhao, W, Zhou, W, Bjornsdottir, G, Boardman, JD, Boehnke, M, Boomsma, DI, Chen, C, Cucca, F, Davies, GE, Eaton, CB, Ehringer, MA, Esko, T, Fiorillo, E, Gillespie, NA, Gudbjartsson, DF, Haller, T, Harris, KM, Heath, AC, Hewitt, JK, Hickie, IB, Hokanson, JE, Hopfer, CJ, Hunter, DJ, Iacono, WG, Johnson, EO, Kamatani, Y, Kardia, SLR, Keller, MC, Kellis, M, Kooperberg, C, Kraft, P, Krauter, KS, Laakso, M, Lind, PA, Loukola, A, Lutz, SM, Madden, PAF, Martin, NG, McGue, M, McQueen, MB, Medland, SE, Metspalu, A, Mohlke, KL, Nielsen, JB, Okada, Y, Peters, U, Polderman, TJC, Posthuma, D, Reiner, AP, Rice, JP, Rimm, E, Rose, RJ, Runarsdottir, V, Stallings, MC, Stančáková, A, Stefansson, H, Thai, KK, Tindle, HA, Tyrfingsson, T, Wall, TL, Weir, DR, Weisner, C, Whitfield, JB, Winsvold, BS, Yin, J, Zuccolo, L, Bierut, LJ, Hveem, K, Lee, JJ, Munafò, MR, Saccone, NL, Willer, CJ, Cornelis, MC, David, SP, Hinds, DA, Jorgenson, E, Kaprio, J, Stitzel, JA, Stefansson, K, Thorgeirsson, TE, Abecasis, G, Liu, DJ, Vrieze, S