Maximising clinical benefit with adequate patient management beyond the second line in mCRC by Guillem Argiles, Dirk Arnold, Gerald Prager, Alberto F Sobrero, Eric Van Cutsem

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Molecular subtypes and the evolution of treatment management in metastatic colorectal cancer by Giulia Martini, Rodrigo Dienstmann, Javier Ros, Iosune Baraibar, Jose Luis Cuadra-Urteaga, Francesc Salva, Davide Ciardiello, Nuria Mulet, Guillem Argiles, Josep Tabernero, Elena Elez

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Analysis of mutant allele fractions in driver genes in colorectal cancer – biological and clinical insights by Rodrigo Dienstmann, Elena Elez, Guillem Argiles, Ignacio Matos, Enrique Sanz‐Garcia, Carolina Ortiz, Teresa Macarulla, Jaume Capdevila, Maria Alsina, Tamara Sauri, Helena Verdaguer, Marta Vilaro, Fiorella Ruiz‐Pace, Cristina Viaplana, Ariadna Garcia, Stefania Landolfi, Hector G. Palmer, Paolo Nuciforo, Jordi Rodon, Ana Vivancos, Josep Tabernero

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Early Clinical Experience with Trifluridine/Tipiracil for Refractory Metastatic Colorectal Cancer: The ROS Study by Pilar García-Alfonso, Andrés Muñoz, Jerónimo Jiménez-Castro, Paula Jiménez-Fonseca, Carles Pericay, Federico Longo-Muñoz, Carmen Reyna-Fortes, Guillem Argilés-Martínez, Beatriz González-Astorga, María José Gómez-Reina, Ana Ruiz-Casado, Nuria Rodríguez-Salas, Rafael López-López, Alberto Carmona-Bayonas, Verónica Conde-Herrero, Enrique Aranda, on behalf of the ROS Study Group

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Impact of circulating tumor DNA mutant allele fraction on prognosis in RAS‐mutant metastatic colorectal cancer by Elena Elez, Chiara Chianese, Enrique Sanz‐García, Erica Martinelli, Alba Noguerido, Francesco Mattia Mancuso, Ginevra Caratù, Judit Matito, Julieta Grasselli, Claudia Cardone, Riziero Esposito Abate, Giulia Martini, Cristina Santos, Teresa Macarulla, Guillem Argilés, Jaume Capdevila, Ariadna Garcia, Nuria Mulet, Evaristo Maiello, Nicola Normanno, Frederick Jones, Josep Tabernero, Fortunato Ciardello, Ramon Salazar, Ana Vivancos

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A Comprehensive Biomarker Analysis of Microsatellite Unstable/Mismatch Repair Deficient Colorectal Cancer Cohort Treated with Immunotherapy by Elena Élez, Núria Mulet-Margalef, Miriam Sanso, Fiorella Ruiz-Pace, Francesco M. Mancuso, Raquel Comas, Javier Ros, Guillem Argilés, Giulia Martini, Enrique Sanz-Garcia, Iosune Baraibar, Francesc Salvà, Alba Noguerido, Jose Luis Cuadra-Urteaga, Roberta Fasani, Ariadna Garcia, Jose Jimenez, Susana Aguilar, Stefania Landolfi, Javier Hernández-Losa, Irene Braña, Paolo Nuciforo, Rodrigo Dienstmann, Josep Tabernero, Ramon Salazar, Ana Vivancos

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Tumor-intrinsic expression of the autophagy gene Atg16l1 suppresses anti-tumor immunity in colorectal cancer by Lucia Taraborrelli, Yasin Şenbabaoğlu, Lifen Wang, Junghyun Lim, Kerrigan Blake, Noelyn Kljavin, Sarah Gierke, Alexis Scherl, James Ziai, Erin McNamara, Mark Owyong, Shilpa Rao, Aslihan Karabacak Calviello, Daniel Oreper, Suchit Jhunjhunwala, Guillem Argiles, Johanna Bendell, Tae Won Kim, Fortunato Ciardiello, Matthew J. Wongchenko, Frederic J. de Sauvage, Felipe de Sousa e Melo, Yibing Yan, Nathaniel R. West, Aditya Murthy

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