The history of oral decitabine/cedazuridine and its potential role in acute myeloid leukemia by Robert Briski, Guillermo Garcia-Manero, Hagop Kantarjian, Farhad Ravandi

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PB2019: PHASE 1B CLINICAL STUDY OF IRAK 1/4 INHIBITION FOR LOW-RISK MYELODYSPLASTIC SYNDROMES REFRACTORY/RESISTANT TO PRIOR THERAPIES: A TRIAL IN PROGRESS by Guillermo Garcia-Manero, Lewis Silverman, Lucy Yan, Wolfgang Dummer

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Relapse and death during first remission in acute myeloid leukemia by Masamitsu Yanada, Guillermo Garcia-Manero, Gautam Borthakur, Farhad Ravandi, Hagop Kantarjian, Elihu Estey

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Accurate identification of locally aneuploid cells by incorporating cytogenetic information in single cell data analysis by Ziyi Li, Ruoxing Li, Irene Ganan-Gomez, Hussein A. Abbas, Guillermo Garcia-Manero, Wei Sun

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Fatigue, symptom burden, and health‐related quality of life in patients with myelodysplastic syndrome, aplastic anemia, and paroxysmal nocturnal hemoglobinuria by Carmen P. Escalante, Stephanie Chisolm, Juhee Song, Marsha Richardson, Ellen Salkeld, Etsuko Aoki, Guillermo Garcia‐Manero

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Research and clinical updates on IRAK4 and its roles in inflammation and malignancy: themes and highlights from the 1st symposium on IRAK4 in cancer by Guillermo Garcia-Manero, Uwe Platzbecker, Kian-Huat Lim, Grzegorz Nowakowski, Omar Abdel-Wahab, Hagop Kantarjian, Amit Verma, Daniel T. Starczynowski

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Improved outcomes with “7+3” induction chemotherapy for acute myeloid leukemia over the past four decades: analysis of SWOG trial data by Megan Othus, Guillermo Garcia-Manero, John E. Godwin, James K. Weick, Frederick R. Appelbaum, Harry P. Erba, Elihu H. Estey

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Metabolic reprogramming and redox adaptation in sorafenib-resistant leukemia cells: detected by untargeted metabolomics and stable isotope tracing analysis by Xin You, Weiye Jiang, Wenhua Lu, Hui Zhang, Tiantian Yu, Jingyu Tian, Shijun Wen, Guillermo Garcia-Manero, Peng Huang, Yumin Hu

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P589: IMPLICATIONS OF REGISTRY DATA FOR ACUTE MYELOID LEUKEMIA (AML) TREATMENT AND CARE DURING THE COVID-19 PANDEMIC by Bart Scott, Mikkael Sekeres, Guillermo Garcia-Manero, David Grinblatt, Irene Degutis, Pavel Kiselev, Ali Mcbride, Willem Heydendael, Edward Yu, Gail Roboz

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Epigenetic inactivation of Notch-Hes pathway in human B-cell acute lymphoblastic leukemia. by Shao-Qing Kuang, Zhihong Fang, Patrick A Zweidler-McKay, Hui Yang, Yue Wei, Emilio A Gonzalez-Cervantes, Yanis Boumber, Guillermo Garcia-Manero

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PB2014: A PHASE 2/3 TRIAL OF ORAL AZACITIDINE IN PATIENTS WITH LOW- OR INTERMEDIATE-RISK MYELODYSPLASTIC SYNDROMES by Guillermo Garcia-Manero, Valeria Santini, Pierre Fenaux, Takahiro Suzuki, Mikkael Sekeres, Jun He, Ronit Barkalifa, Carlos Vigil, Thomas Prebet, Rami S. Komrokji, Aristoteles Giagounidis

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P585: IMPACT OF MYELOID MUTATION PROFILE ON PCR RESPONSES AND SURVIVAL IN PATIENTS WITH CORE-BINDING FACTOR AML TREATED WITH FLAG BASED REGIMES by Jayastu Senapati, Aram Bidikian, Farhad Ravandi, Tapan Kadia, Courtney Dinardo, Guillermo Garcia-Manero, Naval Daver, Naveen Pemmaraju, Elias Jabbour, Mark Brandt, Gautam Borthakur

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Efficacy and safety of generic imatinib after switching from original imatinib in patients treated for chronic myeloid leukemia in the United States by Iman Abou Dalle, Hagop Kantarjian, Jan Burger, Zeev Estrov, Maro Ohanian, Srdan Verstovsek, Farhad Ravandi, Gautam Borthakur, Guillermo Garcia‐Manero, Elias Jabbour, Jorge Cortes

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Overexpression of miR-125a in myelodysplastic syndrome CD34+ cells modulates NF-κB activation and enhances erythroid differentiation arrest. by Irene Gañán-Gómez, Yue Wei, Hui Yang, Sherry Pierce, Carlos Bueso-Ramos, George Calin, George Calin, María Del Carmen Boyano-Adánez, Guillermo García-Manero

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The effect of eltrombopag in managing thrombocytopenia associated with tyrosine kinase therapy in patients with chronic myeloid leukemia and myelofibrosis by Mahran Shoukier, Gautam Borthakur, Elias Jabbour, Farhad Ravandi, Guillermo Garcia-Manero, Tapan Kadia, Jairo Matthews, Lucia Masarova, Kiran Naqvi, Koji Sasaki, Srdan Verstovsek, Jorge Cortes

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P743: CLINICAL OUTCOMES OF PATIENTS WITH MYELODYSPLASTIC SYNDROME AND SPLICEOSOME MUTATIONS by Samuel Urrutia, Emmanuel Almanza, Alex Bataller, Koji Sasaki, Kelly Chien, Rashmi Kanagal-Shamanna, Guillermo Montalban-Bravo, Carlos Bueso-Ramos, Sherry Pierce, Hagop Kantarjian, Guillermo Garcia-Manero

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Fidelity of peripheral blood for monitoring genomics and tumor immune‐microenvironment in myelodysplastic syndromes by Sung‐Eun Lee, Feng Wang, Abel Trujillo‐Ocampo, Wilfredo Ruiz‐Vasquez, Hyun‐Woo Cho, Koichi Takahashi, Jeffrey J. Molldrem, Andrew Futreal, Guillermo Garcia‐Manero, Jin S. Im

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Phase 1 study of an anti-CD33 immunotoxin, humanized monoclonal antibody M195 conjugated to recombinant gelonin (HUM-195/rGEL), in patients with advanced myeloid malignancies by Gautam Borthakur, Michael G. Rosenblum, Moshe Talpaz, Naval Daver, Farhad Ravandi, Stefan Faderl, Emil J. Freireich, Tapan Kadia, Guillermo Garcia-Manero, Hagop Kantarjian, Jorge E. Cortes

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Final report of a phase II study of imatinib mesylate with hyper-CVAD for the front-line treatment of adult patients with Philadelphia chromosome-positive acute lymphoblastic leuke... by Naval Daver, Deborah Thomas, Farhad Ravandi, Jorge Cortes, Rebecca Garris, Elias Jabbour, Guillermo Garcia-Manero, Gautam Borthakur, Tapan Kadia, Michael Rytting, Marina Konopleva, Hagop Kantarjian, Susan O’Brien

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Bone marrow pathologic abnormalities in familial platelet disorder with propensity for myeloid malignancy and germline RUNX1 mutation by Rashmi Kanagal-Shamanna, Sanam Loghavi, Courtney D. DiNardo, L. Jeffrey Medeiros, Guillermo Garcia-Manero, Elias Jabbour, Mark J. Routbort, Rajyalakshmi Luthra, Carlos E. Bueso-Ramos, Joseph D. Khoury

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