Management of hemolytic transfusion reactions in a patient with chronic myelomonocytic leukemia and rare antibodies: A case report by Grace S. Park, Himachandana Atluri, Courtney D. DiNardo, Bryan Guillroy, Jean Horak, Effrosyni Apostolidou, Maryam Buni, Guillermo Montalban Bravo, Naveen Pemmaraju

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P743: CLINICAL OUTCOMES OF PATIENTS WITH MYELODYSPLASTIC SYNDROME AND SPLICEOSOME MUTATIONS by Samuel Urrutia, Emmanuel Almanza, Alex Bataller, Koji Sasaki, Kelly Chien, Rashmi Kanagal-Shamanna, Guillermo Montalban-Bravo, Carlos Bueso-Ramos, Sherry Pierce, Hagop Kantarjian, Guillermo Garcia-Manero

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PB2481: OUTCOMES OF INDIVIDUALS WITH CLONAL HEMATOPOIESIS EVALUATED AT A CANCER CENTER by Kelly Chien, Faustine Ong, Kunhwa Kim, Ziyi LI, Rashmi Kanagal-Shamanna, Courtney Dinardo, Koichi Takahashi, Guillermo Montalban-Bravo, Danielle Hammond, Koji Sasaki, Sherry Pierce, Hagop Kantarjian, Guillermo Garcia-Manero

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The IL-1β inhibitor canakinumab in previously treated lower-risk myelodysplastic syndromes: a phase 2 clinical trial by Juan Jose Rodriguez-Sevilla, Vera Adema, Kelly S. Chien, Sanam Loghavi, Feiyang Ma, Hui Yang, Guillermo Montalban-Bravo, Xuelin Huang, Xavier Calvo, Joby Joseph, Kristy Bodden, Guillermo Garcia-Manero, Simona Colla

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Improving patient understanding and outcomes in myelodysplastic syndromes - An animated patient guide to MDS with visual formats of learning by David A. Sallman, Rafael Bejar, Guillermo Montalban-Bravo, Sandra E. Kurtin, Alan F. List, Guillermo Garcia-Manero, Stephen D. Nimer, Casey L. O'Connell, Dale Schaar, Janice Butchko, Tracey Iraca, Stephanie Searle

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P729: LANDSCAPE OF GERMLINE PATHOGENIC/ LIKELY PATHOGENIC MUTATIONS INVOLVING DNA REPAIR GENES IN SOLID TUMOR PATIENTS WITH ANTECEDENT OR SUBSEQUENT MYELOID NEOPLASMS by Kimberly Hein, Sinchita Roy Chowdhuri, Courtney Dinardo, Guillermo Garcia-Manero, Keyur Patel, Mark Routbort, Richard Yang, Beenu Thakral, Guillermo Montalban-Bravo, Sanam Loghavi, L. Jeffrey Medeiros, Kelly Chien, Rajyalakshmi Luthra, Rashmi Kanagal-Shamanna

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Cancer patients with clonal hematopoiesis die from primary malignancy or comorbidities despite higher rates of transformation to myeloid neoplasms by Kelly S. Chien, Faustine Ong, Kunhwa Kim, Ziyi Li, Rashmi Kanagal‐Shamanna, Courtney D. DiNardo, Koichi Takahashi, Guillermo Montalban‐Bravo, Danielle Hammond, Koji Sasaki, Sherry A. Pierce, Hagop M. Kantarjian, Guillermo Garcia‐Manero

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P728: EVALUATION OF IPSS-M IN PATIENTS WITH MYELODYSPLASTIC SYNDROME AND SPLICEOSOME MUTATIONS by Samuel Urrutia, Ziyi LI, Emmanuel Almanza, Alex Bataller, Rashmi Kanagal-Shamanna, Jayastu Senapati, Koji Sasaki, Kelly Chien, Guillermo Montalban-Bravo, Courtney Dinardo, Gautam Borthakur, Carlos Bueso Ramos, Sherry Pierce, Hagop Kantarjian, Guillermo Garcia-Manero

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S172: PHASE 1/2 STUDY OF ORAL DECITABINE/CEDAZURIDINE IN COMBINATION WITH VENETOCLAX IN TREATMENT-NAÏVE HIGHER-RISK MYELODYSPLASTIC SYNDROMES OR CHRONIC MYELOMONOCYTIC LEUKEMIA by Alex Bataller, Alexandre Bazinet, Sangeetha Venugopal, Guillermo Montalban-Bravo, Yesid Alvarado, Kelly Chien, Ghayas Issa, Nicholas Short, Danielle Hammond, Lucia Masarova, Tapan Kadia, Rashmi Kanagal-Shamanna, Stephany Hendrickson, Farhad Ravandi, Elias Jabbour, Hagop Kantarjian, Guillermo Garcia-Manero

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Liver elastography for risk-assessment of liver toxicity and risk factors for Sinusoidal obstruction syndrome in patients with acute lymphoblastic leukemia receiving inotuzumab ozo... by Jayastu Senapati, Elias Jabbour, Nicholas J. Short, Nitin Jain, Fadi Haddad, Tharakeswara Bathala, Iuliia Kovalenko, Aram Bidikian, Farhad Ravandi, Issa Khouri, Tapan M. Kadia, Rebecca Garris, Guillermo Montalban Bravo, Kelly Chien, Elizabeth Shpall, Partow Kebriaei, Hagop M. Kantarjian

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P748: IPSS-M PERFORMANCE IN PATIENTS WITH MYELODYSPLASTIC SYNDROME AT THE TIME OF HYPOMETHYLATING AGENT FAILURE by Samuel Urrutia, Kelly Chien, Ziyi LI, Alex Bataller, Emmanuel Almanza, Koji Sasaki, Guillermo Montalban-Bravo, Nicholas Short, Elias Jabbour, Tapan Kadia, Farhad Ravandi, Gautam Borthakur, Rashmi Kanagal-Shamanna, Carlos Bueso Ramos, Sherry Pierce, Hagop Kantarjian, Guillermo Garcia-Manero

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S118: A CHEMOTHERAPY-FREE COMBINATION OF PONATINIB AND BLINATUMOMAB FOR PATIENTS WITH NEWLY DIAGNOSED PHILADELPHIA CHROMOSOME-POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA: SUBGROUP ANALYS... by Nicholas Short, Elias Jabbour, Nitin Jain, Xuelin Huang, Walid Macaron, Lewis Nasr, Guillermo Montalban-Bravo, Tapan Kadia, Naval Daver, Kelly Chien, Yesid Alvarado, Ghayas Issa, Fadi Haddad, Cedric Nasnas, Marianne Zoghbi, Rebecca Garris, Marina Konopleva, Farhad Ravandi, Hagop Kantarjian

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P535: OUTCOMES OF INVESTIGATIONAL AGENTS VS STANDARD THERAPIES IN AML AT SALVAGE 2 AND BEYOND by Daniel Nguyen, Hagop Kantarjian, Aram Bidikian, Courtney Dinardo, Tapan Kadia, Naval Daver, Gautam Borthakur, Elias Jabbour, Musa Yilmaz, Nicholas Short, Abhishek Maiti, Koji Sasaki, Guillermo Montalban-Bravo, Danielle Hammond, Sherry Pierce, Michael Andreeff, Guillermo Garcia-Manero, Farhad Ravandi, Ghayas Issa

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P377: A PHASE II TRIAL OF MINI-HYPER-CVD WITH VENETOCLAX FOR PATIENTS WITH RELAPSED/REFRACTORY (R/R) PHILADELPHIA CHROMOSOME (PH)-NEGATIVE ACUTE LYMPHOBLASTIC LEUKEMIA (ALL) by Fadi Haddad, Elias Jabbour, Marianne Zoghbi, Nicholas Short, Jayastu Senapati, Walid Macaron, Cedric Nasnas, Lewis Nasr, Naveen Pemmaraju, Nitin Jain, William G. Wierda, Gautam Borthakur, Guillermo Montalban-Bravo, Farhad Ravandi, Guillermo Garcia-Manero, Tapan Kadia, Kelly Chien, Jennifer Thankachan, Rebecca Garris, Hagop Kantarjian

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Outcomes of patients with acute myeloid leukemia and bone marrow fibrosis by Samuel Urrutia, Hagop M. Kantarjian, Farhad Ravandi-Kashani, Carlos Bueso-Ramos, Rashmi Kanagal-Shamanna, Elias Jabbour, Guillermo Montalban-Bravo, Nicholas J. Short, Naval Daver, Gautam Borthakur, Courtney D. Dinardo, Tapan M. Kadia, Lucia Masarova, Prithviraj Bose, Naveen Pemmaraju, Guillermo Garcia-Manero, Koji Sasaki

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P730: EVOLUTION OF IPSS-M RISK CATEGORIES IN PATIENTS WITH MYELODYSPLASTIC SYNDROMES FROM DIAGNOSIS TO HYPOMETHYLATING AGENT FAILURE by Kelly Chien, Samuel Urrutia, Ziyi LI, Rashmi Kanagal-Shamanna, Emmanuel Almanza, Tareq Abuasab, Georgina Gener, Alex Bataller, Alexandre Bazinet, Guillermo Montalban-Bravo, Nicholas Short, Elias Jabbour, Tapan Kadia, Farhad Ravandi, Gautam Borthakur, Danielle Hammond, Mahesh Swaminathan, Koji Sasaki, Sherry Pierce, Hagop Kantarjian, Guillermo Garcia-Manero

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P736: ANALYSIS OF RESPONSE RATES AND OUTCOMES IN ERYTHROID-PREDOMINANT MYELODYSPLASTIC SYNDROMES (MDS) TREATED WITH VENETOCLAX-BASED REGIMENS by Alexandre Bazinet, Naszrin Arani, Kelly Chien, Danielle Hammond, Tapan Kadia, Gautam Borthakur, Yesid Alvarado, Koji Sasaki, Courtney Dinardo, Naveen Pemmaraju, Lucia Masarova, Nicholas Short, Musa Yilmaz, Naval Daver, Elias Jabbour, Farhad Ravandi, Rashmi Kanagal-Shamanna, Sherry Pierce, Hagop Kantarjian, Guillermo Garcia-Manero, Guillermo Montalban-Bravo

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P485: AZACITIDINE, VENETOCLAX AND GILTERITINIB FOR PATIENTS WITH NEWLY DIAGNOSED FLT3-MUTATED ACUTE MYELOID LEUKEMIA: A SUBGROUP ANALYSIS FROM A PHASE II STUDY by Nicholas Short, Walid Macaron, Courtney Dinardo, Naval Daver, Musa Yilmaz, Gautam Borthakur, Guillermo Montalban-Bravo, Guillermo Garcia-Manero, Ghayas Issa, Koji Sasaki, Jan Burger, Abhishek Maiti, Yesid Alvarado, Jennifer Thankachan, Regina Abramova, Lewis Nasr, Cedric Nasnas, Marianne Zoghbi, Tapan Kadia, Marina Konopleva, Hagop Kantarjian, Farhad Ravandi

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Hematopoietic stem cells with granulo-monocytic differentiation state overcome venetoclax sensitivity in patients with myelodysplastic syndromes by Juan Jose Rodriguez-Sevilla, Irene Ganan-Gomez, Feiyang Ma, Kelly Chien, Monica Del Rey, Sanam Loghavi, Guillermo Montalban-Bravo, Vera Adema, Bethany Wildeman, Rashmi Kanagal-Shamanna, Alexandre Bazinet, Helen T. Chifotides, Natthakan Thongon, Xavier Calvo, Jesús María Hernández-Rivas, Maria Díez-Campelo, Guillermo Garcia-Manero, Simona Colla

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P496: PHENOTYPIC SUBTYPES OF LEUKEMIC TRANSFORMATION IN CHRONIC MYELOMONOCYTIC LEUKEMIA by Guillermo Montalban-Bravo, Rashmi Kanagal-Shamanna, Ziyi LI, Danielle Hammond, Kelly Chien, Juan Jose Rodriguez-Sevilla, Koji Sasaki, Elias Jabbour, Courtney Dinardo, Koichi Takahashi, Nicholas Short, Ghayas Issa, Tapan Kadia, Naveen Pemmaraju, Farhad Ravandi, Naval Daver, Gautam Borthakur, Sanam Loghavi, Sherry Pierce, Carlos Bueso Ramos, Guillermo Garcia-Manero

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