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HIV transmission dynamics and population-wide drug resistance in rural South Africa Por Kemp, SA, Kamelian, K, Cuadros, DF, Cheng, MTK, Okango, E, Hanekom, W, Ndung’u, T, Pillay, D, Bonsall, D, Wong, EB, Tanser, F, Siedner, MJ, Gupta, RK
Publicado em 2024Journal article -
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A G1‐like state allows HIV‐1 to bypass SAMHD1 restriction in macrophages Por Mlcochova, P, Sutherland, KA, Watters, SA, Bertoli, C, de Bruin, RA, Rehwinkel, J, Neil, SJ, Lenzi, GM, Kim, B, Khwaja, A, Gage, MC, Georgiou, C, Chittka, A, Yona, S, Noursadeghi, M, Towers, GJ, Gupta, RK
Publicado em 2017Journal article -
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High prevalence of integrase mutation L74I in West African HIV-1 subtypes prior to integrase inhibitor treatment Por El Bouzidi, K, Kemp, SA, Datir, RP, Murtala-Ibrahim, F, Aliyu, A, Kwaghe, V, Frampton, D, Roy, S, Breuer, J, Sabin, CA, Ogbanufe, O, Charurat, ME, Bonsall, D, Golubchik, T, Fraser, C, Dakum, P, Ndembi, N, Gupta, RK
Publicado em 2020Journal article -
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Collaborative update of a rule-based expert system for HIV-1 genotypic resistance test interpretation Por Paredes, R, Tzou, PL, Van Zyl, G, Barrow, G, Camacho, R, Carmona, S, Grant, PM, Gupta, RK, Hamers, RL, Harrigan, PR, Jordan, MR, Kantor, R, Katzenstein, DA, Kuritzkes, DR, Maldarelli, F, Otelea, D, Wallis, CL, Schapiro, JM, Shafer, RW
Publicado em 2017Journal article -
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B cell receptor repertoire kinetics after SARS-CoV-2 infection and vaccination Por Kotagiri, P, Mescia, F, Rae, WM, Bergamaschi, L, Tuong, ZK, Turner, L, Hunter, K, Gerber, PP, Hosmillo, M, Hess, C, Clatworthy, MR, Goodfellow, IG, Matheson, NJ, McKinney, EF, Wills, MR, Gupta, RK, Bradley, JR, Bashford-Rogers, RJM, Lyons, PA, Smith, KGC
Publicado em 2022Journal article -
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SARS-CoV-2 human challenge reveals biomarkers that discriminate early and late phases of respiratory viral infections Por Rosenheim, J, Gupta, RK, Thakker, C, Mann, T, Bell, LCK, Broderick, CM, Madon, K, Papargyris, L, Dayananda, P, Kwok, AJ, Greenan-Barrett, J, Wagstaffe, HR, Conibear, E, Fenn, J, Hakki, S, Lindeboom, RGH, Dratva, LM, Lemetais, B, Weight, CM, Venturini, C, Kaforou, M, Levin, M, Kalinova, M, Mann, AJ, Knight, JC
Publicado em 2024Journal article -
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HIV-1 drug resistance before initiation or re-initiation of first-line antiretroviral therapy in low-income and middle-income countries: a systematic review and meta-regression ana... Por Gupta, RK, Gregson, J, Parkin, N, Haile-Selassie, H, Tanuri, A, Forero, L, Kaleebu, P, Watera, C, Aghokeng, A, Mutenda, N, Dzangare, J, Hone, S, Hang, ZZ, Garcia, J, Garcia, Z, Marchorro, P, Beteta, E, Giron, A, Hamers, R, Inzaule, S, Frenkel, LM, Chung, MH, de Oliveira, T, Pillay, D, Naidoo, K, Kharsany, A, Kugathasan, R, Cutino, T, Hunt, G, Rios, S, Doherty, M, Jordan, MR, Bertagnolio, S
Publicado em 2017Journal article -
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Innovative vaccine approaches-a Keystone Symposia report Por Cable, J, Rappuoli, R, Klemm, EJ, Kang, G, Mutreja, A, Wright, GJ, Pizza, M, Castro, SA, Hoffmann, JP, Alter, G, Carfi, A, Pollard, AJ, Krammer, F, Gupta, RK, Wagner, CE, Machado, V, Modjarrad, K, Corey, L, B Gilbert, P, Dougan, G, Lurie, N, Bjorkman, PJ, Chiu, C, Nemes, E, Gordon, SB, Steer, AC, Rudel, T, Blish, CA, Sandberg, JT, Brennan, K, Klugman, KP, Stuart, LM, Madhi, SA, Karp, CL
Publicado em 2022Journal article -
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Prospective validation of the 4C prognostic models for adults hospitalised with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol Por Knight, SR, Gupta, RK, Ho, A, Pius, R, Buchan, I, Carson, G, Drake, TM, Dunning, J, Fairfield, CJ, Gamble, C, Green, CA, Halpin, S, Hardwick, HE, Holden, KA, Horby, PW, Jackson, C, Mclean, KA, Merson, L, Nguyen-Van-Tam, JS, Norman, L, Olliaro, PL, Pritchard, MG, Russell, CD, Shaw, CA, Sheikh, A, Solomon, T, Sudlow, C, Swann, OV, Turtle, LCW, Openshaw, PJM, Baillie, JK, Docherty, A, Semple, MG, Noursadeghi, M, Harrison, EM
Publicado em 2021Journal article -
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SARS-CoV-2 evolution during treatment of chronic infection Por Kemp, SA, Collier, DA, Datir, RP, Ferreira, IATM, Gayed, S, Jahun, A, Hosmillo, M, Rees-Spear, C, Mlcochova, P, Lumb, IU, Roberts, DJ, Chandra, A, Temperton, N, Sharrocks, K, Blane, E, Modis, Y, Leigh, KE, Briggs, JAG, van Gils, MJ, Smith, KGC, Bradley, JR, Smith, C, Doffinger, R, Ceron-Gutierrez, L, Barcenas-Morales, G, Pollock, DD, Goldstein, RA, Smielewska, A, Skittrall, JP, Gouliouris, T, Goodfellow, IG, Gkrania-Klotsas, E, Illingworth, CJR, McCoy, LE, Gupta, RK
Publicado em 2021Journal article -
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Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease Por Bergamaschi, L, Mescia, F, Turner, L, Hanson, AL, Kotagiri, P, Dunmore, BJ, Ruffieux, H, De Sa, A, Huhn, O, Morgan, MD, Gerber, PP, Wills, MR, Baker, S, Calero-Nieto, FJ, Doffinger, R, Dougan, G, Elmer, A, Goodfellow, IG, Gupta, RK, Hosmillo, M, Hunter, K, Kingston, N, Lehner, PJ, Matheson, NJ, Nicholson, JK, Petrunkina, AM, Richardson, S, Saunders, C, Thaventhiran, JED, Toonen, EJM, Weekes, MP, Göttgens, B, Toshner, M, Hess, C, Bradley, JR, Lyons, PA, Smith, KGC
Publicado em 2021Journal article -
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Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study Por Gupta, RK, Harrison, EM, Ho, A, Docherty, AB, Knight, SR, van Smeden, M, Abubakar, I, Lipman, M, Quartagno, M, Pius, R, Buchan, I, Carson, G, Drake, TM, Dunning, J, Fairfield, CJ, Gamble, C, Green, CA, Halpin, S, Hardwick, HE, Holden, KA, Horby, PW, Jackson, C, Mclean, KA, Merson, L, Nguyen-Van-Tam, JS, Norman, L, Olliaro, PL, Pritchard, MG, Russell, CD, Scott-Brown, J, Shaw, CA, Sheikh, A, Solomon, T, Sudlow, C, Swann, OV, Turtle, L, Openshaw, PJM, Baillie, JK, Semple, MG, Noursadeghi, M, ISARIC4C Investigators
Publicado em 2021Journal article -
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Genomic characterization and epidemiology of an emerging SARS-CoV-2 variant in Delhi, India Por Dhar, MS, Marwal, R, Vs, R, Ponnusamy, K, Jolly, B, Bhoyar, RC, Sardana, V, Naushin, S, Rophina, M, Mellan, TA, Mishra, S, Whittaker, C, Fatihi, S, Datta, M, Singh, P, Sharma, U, Ujjainiya, R, Bhatheja, N, Divakar, MK, Singh, MK, Imran, M, Senthivel, V, Maurya, R, Jha, N, Mehta, P, A, V, Sharma, P, Vr, A, Chaudhary, U, Soni, N, Thukral, L, Flaxman, S, Bhatt, S, Pandey, R, Dash, D, Faruq, M, Lall, H, Gogia, H, Madan, P, Kulkarni, S, Chauhan, H, Sengupta, S, Kabra, S, Indian SARS-CoV-2 Genomics Consortium (INSACOG)‡, Gupta, RK, Singh, SK, Agrawal, A, Rakshit, P
Publicado em 2021Journal article -
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Combined point-of-care nucleic acid and antibody testing for SARS-CoV-2 following emergence of D614G spike variant Por Mlcochova, P, Collier, D, Ritchie, A, Assennato, SM, Hosmillo, M, Goel, N, Meng, B, Chatterjee, K, Mendoza, V, Temperton, N, Kiss, L, James, LC, Ciazynska, KA, Xiong, X, Briggs, JAG, Nathan, JA, Mescia, F, Bergamaschi, L, Zhang, H, Barmpounakis, P, Demeris, N, Skells, R, Lyons, PA, Bradley, J, Baker, S, Allain, JP, Smith, KGC, Bousfield, R, Wilson, M, Sparkes, D, Amoroso, G, Gkrania-Klotsas, E, Hardwick, S, Boyle, A, Goodfellow, I, Gupta, RK, Baker, S, Dougan, G, Gupta, R, Lehner, PJ, Lyons, P, Matheson, NJ, Toshner, M, Weekes, MP, Brown, N, Curran, M, Palmar, S, Enoch, D, Chapman, D, Shaw, A
Publicado em 2020Journal article -
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Implementation of corticosteroids in treatment of COVID-19 in the ISARIC WHO Clinical Characterisation Protocol UK: prospective, cohort study Por Närhi, F, Moonesinghe, SR, Shenkin, SD, Drake, TM, Mulholland, RH, Donegan, C, Dunning, J, Fairfield, CJ, Girvan, M, Hardwick, HE, Ho, A, Leeming, G, Nguyen-Van-Tam, JS, Pius, R, Russell, CD, Shaw, CA, Spencer, RG, Turtle, L, Openshaw, PJM, Baillie, JK, Harrison, EM, Semple, MG, Docherty, AB, Openshaw, PJ, Carson, G, Alex, B, Andrikopoulos, P, Bach, B, Barclay, WS, Bogaert, D, Chand, M, Chechi, K, Cooke, GS, da Silva Filipe, A, de Silva, T, dos Santos Correia, G, Dumas, ME, Fletcher, T, Green, CA, Greenhalf, W, Griffin, J, Gupta, RK, Hiscox, JA, Ho, AY, Horby, PW, Ijaz, S, Khoo, S, Klenerman, P, Law, A, Lewis, M, Mentzer, AJ, Sigfrid, L
Publicado em 2022Journal article