Beyond growth signaling: apoptotic sensor MERTK activates AKT by a novel mechanism by Yanqiong Zhang, H. Shelton Earp, Pengda Liu

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Co-targeting JAK1/STAT6/GAS6/TAM signaling improves chemotherapy efficacy in Ewing sarcoma by Le Yu, Yu Deng, Xiaodong Wang, Charlene Santos, Ian J. Davis, H. Shelton Earp, Pengda Liu

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Mutation of androgen receptor N-terminal phosphorylation site Tyr-267 leads to inhibition of nuclear translocation and DNA binding. by Mehmet Karaca, Yuanbo Liu, Zhentao Zhang, Dinuka De Silva, Joel S Parker, H Shelton Earp, Young E Whang

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The role of endothelial MERTK during the inflammatory response in lungs. by Yitong Li, Erika S Wittchen, Elizabeth Monaghan-Benson, Cornelia Hahn, H Shelton Earp, Claire M Doerschuk, Keith Burridge

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Inherited predisposition to breast cancer in the Carolina Breast Cancer Study by Tom Walsh, Suleyman Gulsuner, Ming K. Lee, Melissa A. Troester, Andrew F. Olshan, H. Shelton Earp, Charles M. Perou, Mary-Claire King

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Inhibiting efferocytosis reverses macrophage-mediated immunosuppression in the leukemia microenvironment by Joselyn Cruz Cruz, Kristen C. Allison, Lauren S. Page, Alexis J. Jenkins, Xiaodong Wang, H. Shelton Earp, Stephen V. Frye, Douglas K. Graham, Michael R. Verneris, Alisa B. Lee-Sherick

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MERTK Inhibition Induces Polyploidy and Promotes Cell Death and Cellular Senescence in Glioblastoma Multiforme. by Alexandra Sufit, Alisa B Lee-Sherick, Deborah DeRyckere, Manali Rupji, Bhakti Dwivedi, Marileila Varella-Garcia, Angela M Pierce, Jeanne Kowalski, Xiaodong Wang, Stephen V Frye, H Shelton Earp, Amy K Keating, Douglas K Graham

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MERTK activation drives osimertinib resistance in EGFR-mutant non–small cell lung cancer by Dan Yan, Justus M. Huelse, Dmitri Kireev, Zikang Tan, Luxiao Chen, Subir Goyal, Xiaodong Wang, Stephen V. Frye, Madhusmita Behera, Frank Schneider, Suresh S. Ramalingam, Taofeek Owonikoko, H. Shelton Earp, Deborah DeRyckere, Douglas K. Graham

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MERTK inhibition alters the PD-1 axis and promotes anti-leukemia immunity by Alisa B. Lee-Sherick, Kristen M. Jacobsen, Curtis J. Henry, Madeline G. Huey, Rebecca E. Parker, Lauren S. Page, Amanda A. Hill, Xiaodong Wang, Stephen V. Frye, H. Shelton Earp, Craig T. Jordan, Deborah DeRyckere, Douglas K. Graham

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Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation. by Kiran Mahajan, Domenico Coppola, Sridevi Challa, Bin Fang, Y Ann Chen, Weiwei Zhu, Alexis S Lopez, John Koomen, Robert W Engelman, Charlene Rivera, Rebecca S Muraoka-Cook, Jin Q Cheng, Ernst Schönbrunn, Said M Sebti, H Shelton Earp, Nupam P Mahajan

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MERTK mediated novel site Akt phosphorylation alleviates SAV1 suppression by Yao Jiang, Yanqiong Zhang, Janet Y. Leung, Cheng Fan, Konstantin I. Popov, Siyuan Su, Jiayi Qian, Xiaodong Wang, Alisha Holtzhausen, Eric Ubil, Yang Xiang, Ian Davis, Nikolay V. Dokholyan, Gang Wu, Charles M. Perou, William Y. Kim, H. Shelton Earp, Pengda Liu

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Inhibition of Lapatinib-Induced Kinome Reprogramming in ERBB2-Positive Breast Cancer by Targeting BET Family Bromodomains by Timothy J. Stuhlmiller, Samantha M. Miller, Jon S. Zawistowski, Kazuhiro Nakamura, Adriana S. Beltran, James S. Duncan, Steven P. Angus, Kyla A.L. Collins, Deborah A. Granger, Rachel A. Reuther, Lee M. Graves, Shawn M. Gomez, Pei-Fen Kuan, Joel S. Parker, Xin Chen, Noah Sciaky, Lisa A. Carey, H. Shelton Earp, Jian Jin, Gary L. Johnson

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Combined Targeted DNA Sequencing in Non-Small Cell Lung Cancer (NSCLC) Using UNCseq and NGScopy, and RNA Sequencing Using UNCqeR for the Detection of Genetic Aberrations in NSCLC. by Xiaobei Zhao, Anyou Wang, Vonn Walter, Nirali M Patel, David A Eberhard, Michele C Hayward, Ashley H Salazar, Heejoon Jo, Matthew G Soloway, Matthew D Wilkerson, Joel S Parker, Xiaoying Yin, Guosheng Zhang, Marni B Siegel, Gary B Rosson, H Shelton Earp, Norman E Sharpless, Margaret L Gulley, Karen E Weck, D Neil Hayes, Stergios J Moschos

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Factor XIIIA—expressing inflammatory monocytes promote lung squamous cancer through fibrin cross-linking by Alessandro Porrello, Patrick L. Leslie, Emily B. Harrison, Balachandra K. Gorentla, Sravya Kattula, Subrata K. Ghosh, Salma H. Azam, Alisha Holtzhausen, Yvonne L. Chao, Michele C. Hayward, Trent A. Waugh, Sanggyu Bae, Virginia Godfrey, Scott H. Randell, Cecilia Oderup, Liza Makowski, Jared Weiss, Matthew D. Wilkerson, D. Neil Hayes, H. Shelton Earp, Albert S. Baldwin, Alisa S. Wolberg, Chad V. Pecot

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FOXA1 and adaptive response determinants to HER2 targeted therapy in TBCRC 036 by Steven P. Angus, Timothy J. Stuhlmiller, Gaurav Mehta, Samantha M. Bevill, Daniel R. Goulet, J. Felix Olivares-Quintero, Michael P. East, Maki Tanioka, Jon S. Zawistowski, Darshan Singh, Noah Sciaky, Xin Chen, Xiaping He, Naim U. Rashid, Lynn Chollet-Hinton, Cheng Fan, Matthew G. Soloway, Patricia A. Spears, Stuart Jefferys, Joel S. Parker, Kristalyn K. Gallagher, Andres Forero-Torres, Ian E. Krop, Alastair M. Thompson, Rashmi Murthy, Michael L. Gatza, Charles M. Perou, H. Shelton Earp, Lisa A. Carey, Gary L. Johnson

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The Prognostic Significance of Low-Frequency Somatic Mutations in Metastatic Cutaneous Melanoma by Xiaobei Zhao, Paul Little, Alan P. Hoyle, Guillaume J. Pegna, Michele C. Hayward, Anastasia Ivanova, Anastasia Ivanova, Joel S. Parker, David L. Marron, Matthew G. Soloway, Heejoon Jo, Ashley H. Salazar, Michael P. Papakonstantinou, Deeanna M. Bouchard, Stuart R. Jefferys, Katherine A. Hoadley, David W. Ollila, David W. Ollila, David W. Ollila, Jill S. Frank, Jill S. Frank, Nancy E. Thomas, Nancy E. Thomas, Nancy E. Thomas, Paul B. Googe, Paul B. Googe, Paul B. Googe, Ashley J. Ezzell, Frances A. Collichio, Frances A. Collichio, Frances A. Collichio, Carrie B. Lee, Carrie B. Lee, Carrie B. Lee, H. Shelton Earp, Norman E. Sharpless, Willy Hugo, James S. Wilmott, Camelia Quek, Nicola Waddell, Peter A. Johansson, John F. Thompson, Nicholas K. Hayward, Graham J. Mann, Roger S. Lo, Douglas B. Johnson, Richard A. Scolyer, D. Neil Hayes, D. Neil Hayes, Stergios J. Moschos, Stergios J. Moschos, Stergios J. Moschos

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