Evaluation of relative sensitivities and specificities of BRAF mutation detection methodologies, using the paradigm of hairy cell leukaemia by Cardus, B, Colling, R, Soilleux, E, Hamblin, A

Comparison of methodologies for the detection of BRAF mutations in bone marrow trephine specimens by Cardus, B, Colling, R, Hamblin, A, Soilleux, E

Spliceosome mutations are common in persons with myeloproliferative neoplasm-associated myelofibrosis with RBC-transfusion-dependence and correlate with response to pomalidomide by Chowdhury, O, O’Sullivan, J, Barkas, N, Wang, G, Buck, G, Hamblin, A

Colorectal cancer stratification in the routine clinical pathway: A district general hospital experience by Wedden, S, Miller, K, Frayling, I, Thomas, T, Chefani, A, Miller, K, Hamblin, A, Taylor, J, D'Arrigo, C

RAS-pathway mutations are common in patients with ruxolitinib refractory/intolerant myelofibrosis: molecular analysis of the PAC203 cohort by O'Sullivan, JM, Taylor, J, Gerds, A, Buckley, S, Harrison, CN, Oh, S, List, AF, Howard, K, Dreau, H, Hamblin, A, Mead, AJ

Rapid emergence of chronic lymphocytic leukemia during JAK2 inhibitor therapy in a patient with myelofibrosis by Sousos, N, Buck, G, Rodriguez-Meira, A, Norfo, R, Hamblin, A, Pezzella, F, Davies, J, Hublitz, P, Psaila, B, Mead, AJ

Longitudinal mutational analysis in hydroxycarbamide-resistant/intolerant essential thrombocythemia treated on the majic-ET study by O'Sullivan, J, Hamblin, A, Panchal, A, Yap, C, Fox, S, Alimam, S, Dreau, H, Howard, K, Ware, P, Baker, S, Cross, N, McMullin, M, Harrison, C, Mead, A

Unravelling intratumoral heterogeneity through high-sensitivity single-cell mutational analysis and parallel RNA sequencing by Rodriguez-Meira, A, Buck, G, Clark, S, Povinelli, B, Alcolea, V, Louka, E, McGowan, S, Hamblin, A, Sousos, N, Barkas, N, Giustacchini, A, Psaila, B, Jacobsen, S, Thongjuea, S, Mead, A

The poor outcome in high molecular risk, hydroxycarbamide-resistant/intolerant ET is not ameliorated by ruxolitinib by O'Sullivan, JM, Hamblin, A, Yap, C, Fox, S, Boucher, R, Panchal A, Alimam, S, Dreau, H, Howard, K, Ware, P, Cross, NCP, McMullin, MF, Harrison, CN, Mead, AJ

Clinical applicability and cost of a 46-gene panel for genomic analysis of solid tumours: Retrospective validation and prospective audit in the UK National Health Service. by Hamblin, A, Wordsworth, S, Fermont, J, Page, S, Kaur, K, Camps, C, Kaisaki, P, Gupta, A, Talbot, D, Middleton, M, Henderson, S, Cutts, A, Vavoulis, D, Housby, N, Tomlinson, I, Taylor, J, Schuh, A

In utero origin of myelofibrosis presenting in adult monozygotic twins by Sousos, N, Ní Leathlobhair, M, Simoglou Karali, C, Louka, E, Bienz, N, Royston, D, Clark, S-A, Hamblin, A, Howard, K, Mathews, V, George, B, Roy, A, Psaila, B, Wedge, DC, Mead, AJ

Molecular and Functional Characterization of Disease-Propagating Stem Cells in Juvenile Myelomonocytic Leukemia by Louka, E, Povinelli, B, Rodriguez-Meira, A, Buck, G, Hamblin, A, Booth, C, Roy, A, Elliott, N, Iskander, D, de La Fuente, J, Fordham, N, Obyrne, S, Inglott, S, Rao, A, Roberts, I, Mead, A

Ruxolitinib versus best available therapy for ET intolerant or resistant to hydroxycarbamide in a randomized trial by Harrison, C, Mead, A, Panchal, A, Fox, S, Yap, C, Gbandi, E, Houlton, A, Alimam, S, Ewing, J, Wood, M, Chen, F, Coppell, J, Panoskaltsis, N, Knapper, S, Ali, S, Hamblin, A, Scherber, R, Dueck, A, Cross, N, Mesa, R, McMullin, M

Outcome of azacitidine therapy in acute myeloid leukemia is not improved by concurrent vorinostat therapy but is predicted by a diagnostic molecular signature by Craddock, C, Houlton, A, Quek, L, Ferguson, P, Gbandi, E, Roberts, C, Metzner, M, Garcia-Martin, N, Kennedy, A, Hamblin, A, Raghavan, M, Nagra, S, Dudley, L, Wheatley, K, McMullin, M, Pillai, S, Kelly, R, Siddique, S, Dennis, M, Cavenagh, J, Vyas, P

Correlation between treatment outcomes, baseline characteristics and molecular responses in the Majic study which compared Ruxolitinib to best available therapy in essential thromb... by Harrison, C, Mead, A, Fox, S, Panchal, A, Yap, C, Houlton, A, Aliman, S, Ewing, J, Wood, M, Chen, F, Coppell, J, Panoskaltsis, N, Knapper, S, Ali, S, Hamblin, A, Scherber, R, Geyer, H, Scotch, A, Dueck, A, Cross, N, Mesa, R, McMullin, M

Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia by Louka, E, Povinelli, B, Rodriguez-Meira, A, Buck, G, Wen, WX, Wang, G, Sousos, N, Ashley, N, Hamblin, A, Booth, CAG, Roy, A, Elliott, N, Iskander, D, de la Fuente, J, Fordham, N, O’Byrne, S, Inglott, S, Norfo, R, Salio, M, Thongjuea, S, Rao, A, Roberts, I, Mead, AJ

Combination of Deep Phenotyping and Targeted Next Generation Sequencing as a Diagnostic Tool in Children with Suspected MDS by Louka, E, Hamblin, A, Buck, G, Dreau, H, Ware, P, Ancliff, P, Baird, S, Bhatnagar, N, Campbell, H, Caswell, M, Connor, P, Gibson, B, Hall, G, Motwani, J, Norton, A, O'Connor, D, Patrick, K, Pinto, F, Wynn, R, Vora, A, Roberts, I, Mead, A, Rao, A

Clinically actionable mutation profiles in patients with cancer identified by whole-genome sequencing by Schuh, A, Dreau, H, Knight, SJL, Ridout, K, Mizani, T, Vavoulis, D, Colling, R, Antoniou, P, Kvikstad, EM, Pentony, MM, Hamblin, A, Protheroe, A, Parton, M, Shah, KA, Zsolt, O, Athanasou, N, Hassan, B, Flanagan, AM, Ahmed, A, Winter, S, Harris, A, Tomlinson, I, Popitsch, N, Church, DN, Taylor, JC

Spliceosome mutations are common in MPN-associated myelofibrosis with RBC-transfusion-dependence and correlate with response to pomalidomide by Chowdhury, O, O'Sullivan, J, Barkas, N, Buck, G, Hamblin, A, Tefferi, A, Al-Ali, H, Barosi, G, Devos, T, Gisslinger, H, Jiang, Q, Kiladjian, J, Mesa, R, Passamonti, F, Ribrag, V, Schiller, G, Vannucchi, A, Zhou, D, McMullin, M, Reiser, D, Zhong, J, Gale, R, Mead, A

Presence of multiple recurrent mutations confers poor trial outcome of relapsed/refractory CLL. by Guièze, R, Robbe, P, Clifford, R, de Guibert, S, Pereira, B, Timbs, A, Dilhuydy, M, Cabes, M, Ysebaert, L, Burns, A, Nguyen-Khac, F, Davi, F, Véronèse, L, Combes, P, Le Garff-Tavernier, M, Leblond, V, Merle-Béral, H, Alsolami, R, Hamblin, A, Mason, J, Pettitt, A, Hillmen, P, Taylor, J, Knight, S, Tournilhac, O, Schuh, A