Models of Models: A Translational Route for Cancer Treatment and Drug Development by Lesley A. Ogilvie, Aleksandra Kovachev, Christoph Wierling, Bodo M. H. Lange, Hans Lehrach, Hans Lehrach

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Interfering with glycolysis causes Sir2-dependent hyper-recombination of Saccharomyces cerevisiae plasmids. by Markus Ralser, Ute Zeidler, Hans Lehrach

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Modeling of miRNA and drug action in the EGFR signaling pathway. by Jian Li, Vikash Pandey, Thomas Kessler, Hans Lehrach, Christoph Wierling

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Triose phosphate isomerase deficiency is caused by altered dimerization--not catalytic inactivity--of the mutant enzymes. by Markus Ralser, Gino Heeren, Michael Breitenbach, Hans Lehrach, Sylvia Krobitsch

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Combined sequencing of mRNA and DNA from human embryonic stem cells by Florian Mertes, Heiner Kuhl, Wasco Wruck, Hans Lehrach, James Adjaye

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Creation and application of immortalized bait libraries for targeted enrichment and next-generation sequencing by Robert Querfurth, Axel Fischer, Michal R. Schweiger, Hans Lehrach, Florian Mertes

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Generation of a yeast two-hybrid strain suitable for competitive protein binding analysis by Markus Ralser, Heike Goehler, Erich E. Wanker, Hans Lehrach, Sylvia Krobitsch

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The LARGE principle of cellular reprogramming: lost, acquired and retained gene expression in foreskin and amniotic fluid-derived human iPS cells. by Katharina Wolfrum, Ying Wang, Alessandro Prigione, Karl Sperling, Hans Lehrach, James Adjaye

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FOX-2 dependent splicing of ataxin-2 transcript is affected by ataxin-1 overexpression. by Franziska Welzel, Christian Kaehler, Melanie Isau, Linda Hallen, Hans Lehrach, Sylvia Krobitsch

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Predictive Modeling of Drug Treatment in the Area of Personalized Medicine by Lesley A. Ogilvie, Christoph Wierling, Thomas Kessler, Hans Lehrach, Bodo M. H. Lange

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Article Commentary: Predictive Modeling of Drug Treatment in the Area of Personalized Medicine by Lesley A. Ogilvie, Christoph Wierling, Thomas Kessler, Hans Lehrach, Bodo M. H. Lange

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The Saccharomyces cerevisiae W303-K6001 cross-platform genome sequence: insights into ancestry and physiology of a laboratory mutt by Markus Ralser, Heiner Kuhl, Meryem Ralser, Martin Werber, Hans Lehrach, Michael Breitenbach, Bernd Timmermann

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A data integration approach to mapping OCT4 gene regulatory networks operative in embryonic stem cells and embryonal carcinoma cells. by Marc Jung, Hedi Peterson, Lukas Chavez, Pascal Kahlem, Hans Lehrach, Jaak Vilo, James Adjaye

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Ataxin-2-like is a regulator of stress granules and processing bodies. by Christian Kaehler, Jörg Isensee, Ute Nonhoff, Markus Terrey, Tim Hucho, Hans Lehrach, Sylvia Krobitsch

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Exome sequencing from nanogram amounts of starting DNA: comparing three approaches. by Vera N Rykalina, Alexey A Shadrin, Vyacheslav S Amstislavskiy, Evgeny I Rogaev, Hans Lehrach, Tatiana A Borodina

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Combinatorial binding in human and mouse embryonic stem cells identifies conserved enhancers active in early embryonic development. by Jonathan Göke, Marc Jung, Sarah Behrens, Lukas Chavez, Sean O'Keeffe, Bernd Timmermann, Hans Lehrach, James Adjaye, Martin Vingron

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Simple paired heavy- and light-chain antibody repertoire sequencing using endoplasmic reticulum microsomes by Praneeth Reddy Devulapally, Jörg Bürger, Thorsten Mielke, Zoltán Konthur, Hans Lehrach, Marie-Laure Yaspo, Jörn Glökler, Hans-Jörg Warnatz

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Onset of immune senescence defined by unbiased pyrosequencing of human immunoglobulin mRNA repertoires. by Florian Rubelt, Volker Sievert, Florian Knaust, Christian Diener, Theam Soon Lim, Karl Skriner, Edda Klipp, Richard Reinhardt, Hans Lehrach, Zoltán Konthur

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The nerve growth factor receptor CD271 is crucial to maintain tumorigenicity and stem-like properties of melanoma cells. by Torben Redmer, Yvonne Welte, Diana Behrens, Iduna Fichtner, Dorothea Przybilla, Wasco Wruck, Marie-Laure Yaspo, Hans Lehrach, Reinhold Schäfer, Christian R A Regenbrecht

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Mitochondrial-associated cell death mechanisms are reset to an embryonic-like state in aged donor-derived iPS cells harboring chromosomal aberrations. by Alessandro Prigione, Amir M Hossini, Björn Lichtner, Akdes Serin, Beatrix Fauler, Matthias Megges, Rudi Lurz, Hans Lehrach, Eugenia Makrantonaki, Christos C Zouboulis, James Adjaye

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