Concurrent detection of circulating minor histocompatibility antigen-specific CD8+ T cells in SCT recipients by combinatorial encoding MHC multimers. by Kelly Broen, Annelies Greupink-Draaisma, Rob Woestenenk, Nicolaas Schaap, Anthony G Brickner, Harry Dolstra

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Clinical-grade generation of active NK cells from cord blood hematopoietic progenitor cells for immunotherapy using a closed-system culture process. by Jan Spanholtz, Frank Preijers, Marleen Tordoir, Carel Trilsbeek, Jos Paardekooper, Theo de Witte, Nicolaas Schaap, Harry Dolstra

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High log-scale expansion of functional human natural killer cells from umbilical cord blood CD34-positive cells for adoptive cancer immunotherapy. by Jan Spanholtz, Marleen Tordoir, Diana Eissens, Frank Preijers, Arnold van der Meer, Irma Joosten, Nicolaas Schaap, Theo M de Witte, Harry Dolstra

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Cytotoxic T cells are able to efficiently eliminate cancer cells by additive cytotoxicity by Bettina Weigelin, Annemieke Th. den Boer, Esther Wagena, Kelly Broen, Harry Dolstra, Rob J. de Boer, Carl G. Figdor, Johannes Textor, Peter Friedl

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Defining early human NK cell developmental stages in primary and secondary lymphoid tissues. by Diana N Eissens, Jan Spanholtz, Arnold van der Meer, Bram van Cranenbroek, Harry Dolstra, Jaap Kwekkeboom, Frank W M B Preijers, Irma Joosten

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Hematopoietic stem cell-derived myeloid and plasmacytoid DC-based vaccines are highly potent inducers of tumor-reactive T cell and NK cell responses ex vivo by Soley Thordardottir, Nicolaas Schaap, Elja Louer, Michel G. D. Kester, J. H. Frederik Falkenburg, Joop Jansen, Timothy R. D. Radstake, Willemijn Hobo, Harry Dolstra

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Umbilical cord blood CD34+ progenitor-derived NK cells efficiently kill ovarian cancer spheroids and intraperitoneal tumors in NOD/SCID/IL2Rgnull mice by Janneke S. Hoogstad-van Evert, Jeannette Cany, Dirk van den Brand, Manon Oudenampsen, Roland Brock, Ruurd Torensma, Ruud L. Bekkers, Joop H. Jansen, Leon F. Massuger, Harry Dolstra

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A polymorphism in the splice donor site of ZNF419 results in the novel renal cell carcinoma-associated minor histocompatibility antigen ZAPHIR. by Kelly Broen, Henriette Levenga, Johanna Vos, Kees van Bergen, Hanny Fredrix, Annelies Greupink-Draaisma, Michel Kester, J H Frederik Falkenburg, Pieter de Mulder, Theo de Witte, Marieke Griffioen, Harry Dolstra

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Natural killer cells generated from cord blood hematopoietic progenitor cells efficiently target bone marrow-residing human leukemia cells in NOD/SCID/IL2Rg(null) mice. by Jeannette Cany, Anniek B van der Waart, Marleen Tordoir, Gerben M Franssen, Basav N Hangalapura, Jolanda de Vries, Otto Boerman, Nicolaas Schaap, Robbert van der Voort, Jan Spanholtz, Harry Dolstra

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Decreased levels of circulating IL17-producing CD161+CCR6+ T cells are associated with graft-versus-host disease after allogeneic stem cell transplantation. by Anniek B van der Waart, Walter J F M van der Velden, Astrid G S van Halteren, Marij J L G Leenders, Ton Feuth, Nicole M A Blijlevens, Robbert van der Voort, Harry Dolstra

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AKT inhibition generates potent polyfunctional clinical grade AUTO1 CAR T-cells, enhancing function and survival by Harry Dolstra, Claire Roddie, Martin A Pule, Vedika Mehra, Giulia Agliardi, Juliana Dias Alves Pinto, Manar S Shafat, Amaia Cadinanos Garai, Louisa Green, Alastair Hotblack, Fred Arce Vargas, Karl S Peggs, Anniek B van der Waart

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Ex vivo AKT-inhibition facilitates generation of polyfunctional stem cell memory-like CD8+ T cells for adoptive immunotherapy by Charlotte M. Mousset, Willemijn Hobo, Yun Ji, Hanny Fredrix, Valeria De Giorgi, Robert D. Allison, Michel G. D. Kester, J. H. Frederik Falkenburg, Nicolaas P. M. Schaap, Joop H. Jansen, Luca Gattinoni, Harry Dolstra, Anniek B. van der Waart

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Single-cell analysis reveals that stochasticity and paracrine signaling control interferon-alpha production by plasmacytoid dendritic cells by Florian Wimmers, Nikita Subedi, Nicole van Buuringen, Daan Heister, Judith Vivié, Inge Beeren-Reinieren, Rob Woestenenk, Harry Dolstra, Aigars Piruska, Joannes F. M. Jacobs, Alexander van Oudenaarden, Carl G. Figdor, Wilhelm T. S. Huck, I. Jolanda M. de Vries, Jurjen Tel

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TIGIT blockade enhances functionality of peritoneal NK cells with altered expression of DNAM-1/TIGIT/CD96 checkpoint molecules in ovarian cancer by Ralph Ja Maas, Janneke S Hoogstad-van Evert, Jolien Mr Van der Meer, Vera Mekers, Somayeh Rezaeifard, Alan J Korman, Paul Kjd de Jonge, Jeannette Cany, Rob Woestenenk, Nicolaas Pm Schaap, Leon F Massuger, Joop H Jansen, Willemijn Hobo, Harry Dolstra

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Saponin-based adjuvants enhance antigen cross-presentation in human CD11c+ CD1c+ CD5− CD163+ conventional type 2 dendritic cells by Harry Dolstra, Gosse J Adema, Nataschja I Ho, Lisa G M Huis in 't Veld, Jesper van Eck van der Sluijs, Branco M H Heuts, Maaike W G Looman, Esther D Kers-Rebel, Koen van den Dries, Joost H A Martens, Willemijn Hobo

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Reprogramming of bone marrow myeloid progenitor cells in patients with severe coronary artery disease by Marlies P Noz, Siroon Bekkering, Laszlo Groh, Tim MJ Nielen, Evert JP Lamfers, Andreas Schlitzer, Saloua El Messaoudi, Niels van Royen, Erik HJPG Huys, Frank WMB Preijers, Esther MM Smeets, Erik HJG Aarntzen, Bowen Zhang, Yang Li, Manita EJ Bremmers, Walter JFM van der Velden, Harry Dolstra, Leo AB Joosten, Marc E Gomes, Mihai G Netea, Niels P Riksen

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