Scientific rationale for developing potent RBD-based vaccines targeting COVID-19 Autor Harry Kleanthous, Judith Maxwell Silverman, Karen W. Makar, In-Kyu Yoon, Nicholas Jackson, David W. Vaughn

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High-purity preparation of HSV-2 vaccine candidate ACAM529 is immunogenic and efficacious in vivo. Autor Sophia T Mundle, Hector Hernandez, John Hamberger, John Catalan, Changhong Zhou, Svetlana Stegalkina, Andrea Tiffany, Harry Kleanthous, Simon Delagrave, Stephen F Anderson

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Enhancing Immunogenicity of a Thermostable, Efficacious SARS-CoV-2 Vaccine Formulation through Oligomerization and Adjuvant Choice Autor Mohammad Suhail Khan, Virginie Jakob, Randhir Singh, Raju S. Rajmani, Sahil Kumar, Céline Lemoine, Harry Kleanthous, Rajesh P. Ringe, Patrice M. Dubois, Raghavan Varadarajan

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Impact of age and pre-existing immunity on the induction of human antibody responses against influenza B viruses Autor Michael A. Carlock, John G. Ingram, Emily F. Clutter, Noah C. Cecil, Moti Ramgopal, Richard K. Zimmerman, William Warren, Harry Kleanthous, Ted M. Ross

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Antibody-mediated NK cell activation as a correlate of immunity against influenza infection Autor Carolyn M. Boudreau, John S. Burke, Ashraf S. Yousif, Maya Sangesland, Sandra Jastrzebski, Chris Verschoor, George Kuchel, Daniel Lingwood, Harry Kleanthous, Iris De Bruijn, Victoria Landolfi, Saranya Sridhar, Galit Alter

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Application of replication-defective West Nile virus vector to non-flavivirus vaccine targets Autor Maryann Giel-Moloney, Michael Vaine, Linong Zhang, Mark Parrington, Beata Gajewska, Thorsten U. Vogel, Svetlana O. Pougatcheva, Xiaochu Duan, Timothy Farrell, Irina Ustyugova, Sanjay Phogat, Harry Kleanthous, Konstantin V. Pugachev

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Effects of aluminum-salt, CpG and emulsion adjuvants on the stability and immunogenicity of a virus-like particle displaying the SARS-CoV-2 receptor-binding domain (RBD) Autor Ozan S. Kumru, Sakshi Bajoria, Kawaljit Kaur, John M. Hickey, Greta Van Slyke, Jennifer Doering, Katherine Berman, Charles Richardson, Hans Lien, Harry Kleanthous, Nicholas J. Mantis, Sangeeta B. Joshi, David B. Volkin

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Nanoalum Formulations Containing Aluminum Hydroxide and CpG 1018^TM Adjuvants: The Effect on Stability and Immunogenicity of a Recombinant SARS-CoV-2 RBD Antigen Autor Sakshi Bajoria, Ozan S. Kumru, Jennifer Doering, Katherine Berman, Greta Van Slyke, Anneka Prigodich, Sergio A. Rodriguez-Aponte, Harry Kleanthous, J. Christopher Love, Nicholas J. Mantis, Sangeeta B. Joshi, David B. Volkin

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Immunogenicity and efficacy of intramuscular replication-defective and subunit vaccines against herpes simplex virus type 2 in the mouse genital model. Autor Simon Delagrave, Hector Hernandez, Changhong Zhou, John F Hamberger, Sophia T Mundle, John Catalan, Simge Baloglu, Stephen F Anderson, Joshua M DiNapoli, Patricia Londoño-Hayes, Mark Parrington, Jeffrey Almond, Harry Kleanthous

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Novel structural insights for a pair of monoclonal antibodies recognizing non-overlapping epitopes of the glucosyltransferase domain of Clostridium difficile toxin B Autor Jinyu Liu, Michael Kothe, Jianxin Zhang, Eliud Oloo, Svetlana Stegalkina, Sophia T. Mundle, Lu Li, Jinrong Zhang, Leah E. Cole, Lucianna Barone, Hans-Peter Biemann, Harry Kleanthous, Natalie G. Anosova, Stephen F. Anderson

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Enhanced protective efficacy of a thermostable RBD-S2 vaccine formulation against SARS-CoV-2 and its variants Autor Nidhi Mittal, Sahil Kumar, Raju S. Rajmani, Randhir Singh, Céline Lemoine, Virginie Jakob, Sowrabha BJ, Nayana Jagannath, Madhuraj Bhat, Debajyoti Chakraborty, Suman Pandey, Aurélie Jory, Suba Soundarya SA, Harry Kleanthous, Patrice Dubois, Rajesh P. Ringe, Raghavan Varadarajan

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Impact of age and pre-existing influenza immune responses in humans receiving split inactivated influenza vaccine on the induction of the breadth of antibodies to influenza A strai... Autor Ivette A Nuñez, Michael A Carlock, James D Allen, Simon O Owino, Krissy K Moehling, Patricia Nowalk, Michael Susick, Kensington Diagle, Kristen Sweeney, Sophia Mundle, Thorsten U Vogel, Simon Delagrave, Moti Ramgopal, Richard K Zimmerman, Harry Kleanthous, Ted M Ross

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Antigen-adjuvant interactions, stability, and immunogenicity profiles of a SARS-CoV-2 receptor-binding domain (RBD) antigen formulated with aluminum salt and CpG adjuvants Autor Sakshi Bajoria, Kawaljit Kaur, Ozan S. Kumru, Greta Van Slyke, Jennifer Doering, Hayley Novak, Sergio A. Rodriguez Aponte, Neil C. Dalvie, Christopher A. Naranjo, Ryan S. Johnston, Judith Maxwell Silverman, Harry Kleanthous, J. Christopher Love, Nicholas J. Mantis, Sangeeta B. Joshi, David B. Volkin

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Three immunizations with Novavax’s protein vaccines increase antibody breadth and provide durable protection from SARS-CoV-2 Autor Klara Lenart, Rodrigo Arcoverde Cerveira, Fredrika Hellgren, Sebastian Ols, Daniel J. Sheward, Changil Kim, Alberto Cagigi, Matthew Gagne, Brandon Davis, Daritza Germosen, Vicky Roy, Galit Alter, Hélène Letscher, Jérôme Van Wassenhove, Wesley Gros, Anne-Sophie Gallouët, Roger Le Grand, Harry Kleanthous, Mimi Guebre-Xabier, Ben Murrell, Nita Patel, Gregory Glenn, Gale Smith, Karin Loré

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Immunogenicity and protective efficacy of GBP510/AS03 vaccine against SARS-CoV-2 delta challenge in rhesus macaques Autor Catherine Jacob-Dolan, Jingyou Yu, Katherine McMahan, Victoria Giffin, Abishek Chandrashekar, Amanda J. Martinot, Tochi Anioke, Olivia C. Powers, Kevin Hall, David Hope, Jessica Miller, Nichole P. Hachmann, Benjamin Chung, Sarah Gardner, Daniel Sellers, Julia Barrett, Mark G. Lewis, Hanne Andersen, Harry Kleanthous, Ki-Woen Seo, Su Jeen Lee, Yong Wook Park, Hun Kim, Dan H. Barouch

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Adjuvanting a subunit SARS-CoV-2 vaccine with clinically relevant adjuvants induces durable protection in mice Autor Lilit Grigoryan, Audrey Lee, Alexandra C. Walls, Lilin Lai, Benjamin Franco, Prabhu S. Arunachalam, Yupeng Feng, Wei Luo, Abigail Vanderheiden, Katharine Floyd, Samuel Wrenn, Deleah Pettie, Marcos C. Miranda, Elizabeth Kepl, Rashmi Ravichandran, Claire Sydeman, Natalie Brunette, Michael Murphy, Brooke Fiala, Lauren Carter, Robert L. Coffman, David Novack, Harry Kleanthous, Derek T. O’Hagan, Robbert van der Most, Jason S. McLellan, Mehul Suthar, David Veesler, Neil P. King, Bali Pulendran

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