Fusion pore in exocytosis: more than an exit gate? A β-cell perspective by Hastoy, B, Clark, A, Rorsman, P, Lang, J

The β-cell assassin: IAPP cytotoxicity by Raleigh, D, Zhang, X, Hastoy, B, Clark, A

Electrophysiological characterization of the human beta cell line EndoC-βH2 by Hastoy, B, Chibalina, M, Godazgar, M, Scharfmann, R, Rorsman, P

A CRISPR/Cas9 genome editing pipeline in the EndoC-βH1 cell line to study genes implicated in beta cell function by Grotz, A, Abaitua, F, Navarro-Guerrero, E, Hastoy, B, Ebner, D, Gloyn, A

The transmembrane domain of the SNARE protein VAMP2 is highly sensitive to its lipid environment by Fezoua-Boubegtiten, Z, Hastoy, B, Scotti, P, Milochau, A, Bathany, K, Desbat, B, Castano, S, Oda, R, Lang, J

Insulin prevents counter-regulatory glucagon secretion by stimulation of somatostatin release by Rorsman, P, Vergari, E, Brereton, M, Zhang, Q, Hastoy, B, Ramracheya, R, Salehi, A, Clark, A, Ashcroft, F

AP2σ mutations impair calcium-sensing receptor trafficking and signaling, and reveal an endosomal pathway that spatially-directs G-protein selectivity by Gorvin, C, Rogers, A, Hastoy, B, Tarasov, A, Frost, M, Sposini, S, Inoue, A, Whyte, M, Rorsman, O, Hanyaloglu, A, Breitwieser, G, Thakker, R

A central small amino acid in the VAMP2 transmembrane domain regulates the fusion pore in exocytosis by Hastoy, B, Scotti, P, Milochau, A, Fezoua-Boubegtiten, Z, Rodas, J, Megret, R, Desbat, B, Laguerre, M, Castano, S, Perrais, D, Rorsman, P, Oda, R, Lang, J

RFX6 Regulates Insulin Secretion by Modulating Ca(2+) Homeostasis in Human β Cells. by Chandra, V, Albagli-Curiel, O, Hastoy, B, Piccand, J, Randriamampita, C, Vaillant, E, Cavé, H, Busiah, K, Froguel, P, Vaxillaire, M, Rorsman, P, Polak, M, Scharfmann, R

MicroRNA-7a regulates pancreatic β cell function. by Latreille, M, Hausser, J, Stützer, I, Zhang, Q, Hastoy, B, Gargani, S, Kerr-Conte, J, Pattou, F, Zavolan, M, Esguerra, J, Eliasson, L, Rülicke, T, Rorsman, P, Stoffel, M

RFX6 Regulates Insulin Secretion by Modulating Ca2+ Homeostasis in Human β Cells by Chandra, V, Albagli-Curiel, O, Hastoy, B, Piccand, J, Randriamampita, C, Vaillant, E, Cavé, H, Busiah, K, Froguel, P, Vaxillaire, M, Rorsman, P, Polak, M, Scharfmann, R

Increased expression of the diabetes gene SOX4 reduces insulin secretion by impaired fusion pore expansion by Collins, S, Do, H, Hastoy, B, Hugill, A, Adam, J, Chibalina, M, Galvanovskis, J, Godazgar, M, Lee, S, Goldsworthy, M, Salehi, A, Tarasov, A, Rosengren, A, Cox, R, Rorsman, P

Electrophysiological properties of human beta-cell lines EndoC-βH1 and -βH2 conform with human beta-cells by Hastoy, B, Godazgar, M, Clark, A, Nylander, V, Spiliotis, I, Van De Bunt, M, Chibalina, M, Barrett, A, Burrows, C, Tarasov, A, Scharfmann, R, Gloyn, A, Rorsman, O

Electrophysiological properties of human beta-cell lines EndoC-βH1 and -βH2 conform with human beta-cells by Hastoy, B, Godazgar, M, Clark, A, Nylander, V, Spiliotis, I, Van De Bunt, M, Chibalina, M, Barrett, A, Burrows, C, Tarasov, A, Scharfmann, R, Gloyn, A, Rorsman, P

Increased expression of the diabetes gene SOX4 reduces insulin secretion by impaired fusion pore expansion by Collins, S, Do, H, Hastoy, B, Hugill, A, Adam, J, Chibalina, M, Galvanovskis, J, Godazgar, M, Lee, S, Goldsworthy, M, Salehi, A, Tarasov, A, Rosengren, A, Cox, R, Rorsman, P

Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion by Vergari, E, Knudsen, J, Ramracheya, R, Salehi, A, Zhang, Q, Adam, J, Asterholm, I, Benrick, A, Briant, L, Chibalina, M, Gribble, F, Hamilton, A, Hastoy, B, Reimann, F, Rorsman, N, Spiliotis, I, Tarasov, A, Wu, Y, Ashcroft, F, Rorsman, P

Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic beta cells by Thomsen, S, Raimondo, A, Hastoy, B, Sengupta, S, Dai, X, Bautista, A, Censin, J, Payne, A, Umapathysivam, M, Spigelman, A, Barrett, A, Groves, C, Beer, N, Manning Fox, J, McCarthy, M, Clark, A, Mahajan, A, Rorsman, O, MacDonald, P, Gloyn, A

Glutamate acts as a key signal linking glucose metabolism to incretin/cAMP action to amplify insulin secretion. by Gheni, G, Ogura, M, Iwasaki, M, Yokoi, N, Minami, K, Nakayama, Y, Harada, K, Hastoy, B, Wu, X, Takahashi, H, Kimura, K, Matsubara, T, Hoshikawa, R, Hatano, N, Sugawara, K, Shibasaki, T, Inagaki, N, Bamba, T, Mizoguchi, A, Fukusaki, E, Rorsman, P, Seino, S

NKX6.1 induced pluripotent stem cell reporter lines for isolation and analysis of functionally relevant neuronal and pancreas populations by Gupta, S, Wesolowska-Andersen, A, Ringgaard, A, Jaiswal, H, Song, L, Hastoy, B, Ingvorsen, C, Taheri-Ghahfarokhi, A, Magnusson, B, Maresca, M, Jensen, R, Beer, N, Fels, J, Grunnet, L, Thomas, M, Gloyn, A, Hicks, R, McCarthy, M, Hansson, M, Honoré, C

GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation by Zaccolo, M, Shigeto, M, Ramracheya, R, Tarasov, A, Cha, C, Chibalina, M, Hastoy, B, Philippaert, K, Reinbothe, T, Rorsman, N, Salehi, A, Sones, W, Vergari, E, Weston, C, Gorelik, J, Katsura, M, Nikolaev, V, Vennekens, R, Galione, A, Johnson, P, Kaku, K, Ladds, G, Rorsman, P