IGF2/H19 hypomethylation in a patient with very low birthweight, preocious pubarche and insulin resistance door Murphy Rinki, Ibáñez Lourdes, Hattersley Andrew, Tost Jörg

Volledige tekst

Multimodal analysis in symptomatic MIDD-associated retinopathy. A case report and literature review door Chwiejczak, Katarzyna, Byles, Daniel, Gerry, Paul, Von Lany, Hirut, Tasiopoulou, Anastasia, Hattersley, Andrew

Volledige tekst

Assessing newborn body composition using principal components analysis: differences in the determinants of fat and skeletal size door Powell Roy J, Knight Bridget A, Shields Beverley M, Hattersley Andrew T, Wright David E

Volledige tekst

Permanent neonatal diabetes: combining sulphonylureas with insulin may be an effective treatment door Misra, S, vedovato, natascia, cliff, edward, de franco, elise, hattersley, andrew, ashcroft, fran, Oliver, nick

Volledige tekst
Volledige tekst

Genetic variants in <it>Apolipoprotein AV </it>alter triglyceride concentrations in pregnancy door Hattersley Andrew T, Salzmann Maurice B, Knight Beatrice, Shields Beverley, Ward Kirsten J, Frayling Timothy M

Volledige tekst

Allelic drop-out may occur with a primer binding site polymorphism for the commonly used RFLP assay for the -1131T>C polymorphism of the <it>Apolipoprotein AV </it>gene door Hattersley Andrew T, Frayling Timothy M, Yajnik Chittaranjan S, Ellard Sian, Ward Kirsten J, Venigalla Prathyusha NS, Chandak Giriraj R

Volledige tekst

Assessment of endogenous insulin secretion in insulin treated diabetes predicts postprandial glucose and treatment response to prandial insulin door Jones Angus G, Besser Rachel EJ, Shields Beverley M, McDonald Timothy J, Hope Suzy V, Knight Bridget A, Hattersley Andrew T

Volledige tekst

The functional "KL-VS" variant of <it>KLOTHO </it>is not associated with type 2 diabetes in 5028 UK Caucasians door Walker Mark, Hitman Graham A, Shields Beverley, Melzer David, Weedon Michael N, Freathy Rachel M, McCarthy Mark I, Hattersley Andrew T, Frayling Timothy M

Volledige tekst

The relationship between islet autoantibody status and the genetic risk of type 1 diabetes in adult-onset type 1 diabetes door Thomas, Nicholas J, Walkey, Helen C, Kaur, Akaal, Misra, Shivani, Oliver, Nick S, Colclough, Kevin, Weedon, Michael N, Johnston, Desmond G, Hattersley, Andrew T, Patel, Kashyap A

Volledige tekst
Volledige tekst
Volledige tekst
Volledige tekst

Common maternal and fetal genetic variants show expected polygenic effects on risk of small- or large-for-gestational-age (SGA or LGA), except in the smallest 3% of babies door Beaumont, Robin N, Kotecha, Sarah J, Wood, Andrew R, Knight, Bridget A, Sebert, Sylvain, McCarthy, Mark, Hattersley, Andrew T, Jarvelin, Marjo-Riitta, Timpson, Nicholas J, Freathy, Rachel M, Kotecha, Sailesh

Volledige tekst
Volledige tekst
Volledige tekst
Volledige tekst

GATA6 cooperates with EOMES/SMAD2/3 to deploy the gene regulatory network governing human definitive endoderm and pancreas formation door Chia, Crystal Y., Madrigal, Pedro, Denil, Simon L.I.J., Martinez, Iker, Garcia-Bernardo, Jose, El-Khairi, Ranna, Chhatriwala, Mariya, Shepherd, Maggie H., Hattersley, Andrew T., Vallier, Ludovic, Dunn, Norris Ray

Volledige tekst
Volledige tekst

Triglyceride associated polymorphisms of the <it>APOA5 </it>gene have very different allele frequencies in Pune, India compared to Europeans door Chandak Giriraj R, Ward Kirsten J, Yajnik Chittaranjan S, Pandit Anand N, Bavdekar Ashish, Joglekar Charu V, Fall Caroline HD, Mohankrishna P, Wilkin Terence J, Metcalf Bradley S, Weedon Michael N, Frayling Timothy M, Hattersley Andrew T

Volledige tekst

Genome-wide and abdominal MRI data provide evidence that a genetically determined favorable adiposity phenotype is characterized by lower ectopic liver fat and lower risk of type 2... door Ji, Yingjie, Yiorkas, Andrianos M, Frau, Francesca, Mook-Kanamori, Dennis, Staiger, Harald, Thomas, E Louise, Atabaki-Pasdar, Naeimeh, Campbell, Archie, Tyrrell, Jessica, Jones, Samuel E, Beaumont, Robin N, Wood, Andrew R, Tuke, Marcus A, Ruth, Katherine S, Mahajan, Anubha, Murray, Anna, Freathy, Rachel M, Weedon, Michael N, Hattersley, Andrew T, Hayward, Caroline, Machann, Juergen, Haering, Hans-Ulrich, Franks, Paul, de Mutsert, Renee, Pearson, Ewan, Stefan, Norbert, Frayling, Timothy M, Allebrandt, Karla V, Bell, Jimmy D, Blakemore, Alexandra I, Yaghootkar, Hanieh

Volledige tekst
Volledige tekst
Volledige tekst
Volledige tekst

The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study door Koivula, Robert W, Atabaki-Pasdar, Naeimeh, Giordano, Giuseppe N, White, Tom, Adamski, Jerzy, Bell, Jimmy D, Beulens, Joline, Brage, Soren, Brunak, Soren, De Masi, Federico, Dermitzakis, Emmanouil T, Forgie, Ian M, Frost, Gary, Hansen, Torben, Hansen, Tue H, Hattersley, Andrew, Kokkola, Tarja, Kurbasic, Azra, Laakso, Markku, Mari, Andrea, McDonald, Timothy J, Pedersen, Oluf, Rutters, Femke, Schwenk, Jochen M, Teare, Harriet JA, Thomas, E Louise, Vinuela, Ana, Mahajan, Anubha, McCarthy, Mark I, Ruetten, Hartmut, Walker, Mark, Pearson, Ewan, Pavo, Imre, Franks, Paul W

Volledige tekst
Volledige tekst
Volledige tekst
Volledige tekst

Genetic variation in the 15q25 nicotinic acetylcholine receptor gene cluster (CHRNA5CHRNA3CHRNB4) interacts with maternal self-reported smoking status during pregnancy to influence... door Tyrrell, Jessica, Huikari, Ville, Christie, Jennifer T, Cavadino, Alana, Bakker, Rachel, Brion, Marie-Jo A, Geller, Frank, Paternoster, Lavinia, Myhre, Ronny, Potter, Catherine, Johnson, Paul CD, Ebrahim, Shah, Feenstra, Bjarke, Hartikainen, Anna-Liisa, Hattersley, Andrew T, Hofman, Albert, Kaakinen, Marika, Lowe, Lynn P, Magnus, Per, McConnachie, Alex, Melbye, Mads, Ng, Jane WY, Nohr, Ellen A, Power, Chris, Ring, Susan M, Sebert, Sylvain P, Sengpiel, Verena, Taal, H Rob, Watt, Graham CM, Sattar, Naveed, Relton, Caroline L, Jacobsson, Bo, Frayling, Timothy M, Srensen, Thorkild IA, Murray, Jeffrey C, Lawlor, Debbie A, Pennell, Craig E, Jaddoe, Vincent WV, Hypponen, Elina, Lowe, William L, Jarvelin, Marjo-Riitta, Smith, George Davey, Freathy, Rachel M

Volledige tekst
Volledige tekst
Volledige tekst
Volledige tekst

Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT... door Koivula, Robert W, Forgie, Ian M, Kurbasic, Azra, Viñuela, Ana, Heggie, Alison, Giordano, Giuseppe N, Hansen, Tue H, Hudson, Michelle, Koopman, Anitra DM, Rutters, Femke, Siloaho, Maritta, Allin, Kristine H, Brage, Søren, Brorsson, Caroline A, Dawed, Adem Y, De Masi, Federico, Groves, Christopher J, Kokkola, Tarja, Mahajan, Anubha, Perry, Mandy H, Rauh, Simone P, Ridderstråle, Martin, Teare, Harriet JA, Thomas, E Louise, Tura, Andrea, Vestergaard, Henrik, White, Tom, Adamski, Jerzy, Bell, Jimmy D, Beulens, Joline W, Brunak, Søren, Dermitzakis, Emmanouil T, Froguel, Philippe, Frost, Gary, Gupta, Ramneek, Hansen, Torben, Hattersley, Andrew, Jablonka, Bernd, Kaye, Jane, Laakso, Markku, McDonald, Timothy J, Pedersen, Oluf, Schwenk, Jochen M, Pavo, Imre, Mari, Andrea, McCarthy, Mark I, Ruetten, Hartmut, Walker, Mark, Pearson, Ewan, Franks, Paul W, IMI DIRECT Consortium

Volledige tekst
Volledige tekst
Volledige tekst
Volledige tekst

Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes door Perry, John RB, Weedon, Michael N, Langenberg, Claudia, Jackson, Anne U, Lyssenko, Valeriya, Sparso, Thomas, Thorleifsson, Gudmar, Grallert, Harald, Ferrucci, Luigi, Maggio, Marcello, Paolisso, Giuseppe, Walker, Mark, Palmer, Colin NA, Payne, Felicity, Young, Elizabeth, Herder, Christian, Narisu, Narisu, Morken, Mario A, Bonnycastle, Lori L, Owen, Katharine R, Shields, Beverley, Knight, Beatrice, Bennett, Amanda, Groves, Christopher J, Ruokonen, Aimo, Jarvelin, Marjo Riitta, Pearson, Ewan, Pascoe, Laura, Ferrannini, Ele, Bornstein, Stefan R, Stringham, Heather M, Scott, Laura J, Kuusisto, Johanna, Nilsson, Peter, Neptin, Malin, Gjesing, Anette P, Pisinger, Charlotta, Lauritzen, Torsten, Sandbaek, Annelli, Sampson, Mike, Magic, Ele Zeggini, Lindgren, Cecilia M, Steinthorsdottir, Valgerdur, Thorsteinsdottir, Unnur, Hansen, Torben, Schwarz, Peter, Illig, Thomas, Laakso, Markku, Stefansson, Kari, Morris, Andrew D, Groop, Leif, Pedersen, Oluf, Boehnke, Michael, Barroso, Ines, Wareham, Nicholas J, Hattersley, Andrew T, McCarthy, Mark I, Frayling, Timothy M

Volledige tekst
Volledige tekst
Volledige tekst
Volledige tekst

Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts door Atabaki-Pasdar, Naeimeh, Ohlsson, Mattias, Vinuela, Ana, Frau, Francesca, Pomares-Millan, Hugo, Haid, Mark, Jones, Angus G, Thomas, E Louise, Koivula, Robert W, Kurbasic, Azra, Mutie, Pascal M, Fitipaldi, Hugo, Fernandez, Juan, Dawed, Adem Y, Giordano, Giuseppe N, Forgie, Ian M, McDonald, Timothy J, Rutters, Femke, Cederberg, Henna, Chabanova, Elizaveta, Dale, Matilda, Masi, Federico De, Thomas, Cecilia Engel, Allin, Kristine H, Hansen, Tue H, Heggie, Alison, Hong, Mun-Gwan, Elders, Petra JM, Kennedy, Gwen, Kokkola, Tarja, Pedersen, Helle Krogh, Mahajan, Anubha, McEvoy, Donna, Pattou, Francois, Raverdy, Violeta, Haussler, Ragna S, Sharma, Sapna, Thomsen, Henrik S, Vangipurapu, Jagadish, Vestergaard, Henrik, 't Hart, Leen M, Adamski, Jerzy, Musholt, Petra B, Brage, Soren, Brunak, Soren, Dermitzakis, Emmanouil, Frost, Gary, Hansen, Torben, Laakso, Markku, Pedersen, Oluf, Ridderstrale, Martin, Ruetten, Hartmut, Hattersley, Andrew T, Walker, Mark, Beulens, Joline WJ, Mari, Andrea, Schwenk, Jochen M, Gupta, Ramneek, McCarthy, Mark I, Pearson, Ewan R, Bell, Jimmy D, Pavo, Imre, Franks, Paul W

Volledige tekst
Volledige tekst
Volledige tekst
Volledige tekst

Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth door Beaumont, Robin N, Flatley, Christopher, Vaudel, Marc, Wu, Xiaoping, Chen, Jing, Moen, Gunn-Helen, Skotte, Line, Helgeland, Oyvind, Sole-Navais, Pol, Banasik, Karina, Albinana, Clara, Ronkainen, Justiina, Fadista, Joao, Stinson, Sara Elizabeth, Trajanoska, Katerina, Wang, Carol A, Westergaard, David, Srinivasan, Sundararajan, Sanchez-Soriano, Carlos, Bilbao, Jose Ramon, Allard, Catherine, Groleau, Marika, Kuulasmaa, Teemu, Leirer, Daniel J, White, Frederique, Jacques, Pierre-etienne, Cheng, Haoxiang, Hao, Ke, Andreassen, Ole A, Asvold, Bjorn Olav, Atalay, Mustafa, Bhatta, Laxmi, Bouchard, Luigi, Brumpton, Ben Michael, Brunak, Soren, Bybjerg-Grauholm, Jonas, Ebbing, Cathrine, Elliott, Paul, Engelbrechtsen, Line, Erikstrup, Christian, Estarlich, Marisa, Franks, Stephen, Gaillard, Romy, Geller, Frank, Grove, Jakob, Hougaard, David M, Kajantie, Eero, Morgen, Camilla S, Nohr, Ellen A, Nyegaard, Mette, Palmer, Colin NA, Pedersen, Ole Birger, Rivadeneira, Fernando, Sebert, Sylvain, Shields, Beverley M, Stoltenberg, Camilla, Surakka, Ida, Thorner, Lise Wegner, Ullum, Henrik, Vaarasmaki, Marja, Vilhjalmsson, Bjarni J, Willer, Cristen J, Lakka, Timo A, Gybel-Brask, Dorte, Bustamante, Mariona, Hansen, Torben, Pearson, Ewan R, Reynolds, Rebecca M, Ostrowski, Sisse R, Pennell, Craig E, Jaddoe, Vincent WV, Felix, Janine F, Hattersley, Andrew T, Melbye, Mads, Lawlor, Deborah A, Hveem, Kristian, Werge, Thomas, Nielsen, Henriette Svarre, Magnus, Per, Evans, David M, Jacobsson, Bo, Jaervelin, Marjo-Riitta, Zhang, Ge, Hivert, Marie-France, Johansson, Stefan, Freathy, Rachel M, Feenstra, Bjarke, Njolstad, Pal R

Volledige tekst
Volledige tekst
Volledige tekst
Volledige tekst

Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics door Beaumont, Robin N, Warrington, Nicole M, Cavadino, Alana, Tyrrell, Jessica, Nodzenski, Michael, Horikoshi, Momoko, Geller, Frank, Myhre, Ronny, Richmond, Rebecca C, Paternoster, Lavinia, Bradfield, Jonathan P, Kreiner-Moller, Eskil, Huikari, Ville, Metrustry, Sarah, Lunetta, Kathryn L, Painter, Jodie N, Hottenga, Jouke-Jan, Allard, Catherine, Barton, Sheila J, Espinosa, Ana, Marsh, Julie A, Potter, Catherine, Zhang, Ge, Ang, Wei, Berry, Diane J, Bouchard, Luigi, Das, Shikta, Hakonarson, Hakon, Heikkinen, Jani, Helgeland, Oyvind, Hocher, Berthold, Hofman, Albert, Inskip, Hazel M, Jones, Samuel E, Kogevinas, Manolis, Lind, Penelope A, Marullo, Letizia, Medland, Sarah E, Murray, Anna, Murray, Jeffrey C, Njolstad, Pal R, Nohr, Ellen A, Reichetzeder, Christoph, Ring, Susan M, Ruth, Katherine S, Santa-Marina, Loreto, Scholtens, Denise M, Sebert, Sylvain, Sengpiel, Verena, Tuke, Marcus A, Vaudel, Marc, Weedon, Michael N, Willemsen, Gonneke, Wood, Andrew R, Yaghootkar, Hanieh, Muglia, Louis J, Bartels, Meike, Relton, Caroline L, Pennell, Craig E, Chatzi, Leda, Estivill, Xavier, Holloway, John W, Boomsma, Dorret I, Montgomery, Grant W, Murabito, Joanne M, Spector, Tim D, Power, Christine, Jarvelin, Marjo-Ritta, Bisgaard, Hans, Grant, Struan FA, Sorensen, Thorkild IA, Jaddoe, Vincent W, Jacobsson, Bo, Melbye, Mads, McCarthy, Mark I, Hattersley, Andrew T, Hayes, M Geoffrey, Frayling, Timothy M, Hivert, Marie-France, Felix, Janine F, Hypponen, Elina, Lowe, William L, Evans, David M, Lawlor, Debbie A, Feenstra, Bjarke, Freathy, Rachel M

Volledige tekst
Volledige tekst
Volledige tekst
Volledige tekst