Mechanisms of the autophagosome-lysosome fusion step and its relation to non-alcoholic fatty liver disease by Hayato Hikita, Sadatsugu Sakane, Tetsuo Takehara

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Increased Bcl-xL Expression in Pancreatic Neoplasia Promotes Carcinogenesis by Inhibiting Senescence and ApoptosisSummary by Kenji Ikezawa, Hayato Hikita, Minoru Shigekawa, Kiyoshi Iwahashi, Hidetoshi Eguchi, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara

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Utility and clinical significance of endoscopic ultrasound-guided tissue acquisition for diagnosing lymphadenopathies in biliary tract cancer by Katsuhiko Sato, Minoru Shigekawa, Syuhei Yamamoto, Takayuki Matsumae, Yu Sato, Teppei Yoshioka, Takahiro Kodama, Hayato Hikita, Tomohide Tatsumi, Tetsuo Takehara

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Evaluation of Fucosylated Haptoglobin and Mac-2 Binding Protein as Serum Biomarkers to Estimate Liver Fibrosis in Patients with Chronic Hepatitis C. by Seiichi Tawara, Tomohide Tatsumi, Sadaharu Iio, Ichizou Kobayashi, Minoru Shigekawa, Hayato Hikita, Ryotaro Sakamori, Naoki Hiramatsu, Eiji Miyoshi, Tetsuo Takehara

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Endoscopic submucosal dissection for early gastric cancer in a patient after left ventricular assist device implantation: A case report by Shinji Kuriki, Yoshiki Tsujii, Hirotsugu Saiki, Takahiro Amano, Ryotaro Uema, Minoru Kato, Takeo Yoshihara, Yoshito Hayashi, Hayato Hikita, Tetsuo Takehara

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Intrahepatic Exhausted Antiviral Immunity in an Immunocompetent Mouse Model of Chronic Hepatitis BSummary by Satoshi Shigeno, Takahiro Kodama, Kazuhiro Murai, Daisuke Motooka, Akihisa Fukushima, Akira Nishio, Hayato Hikita, Tomohide Tatsumi, Toru Okamoto, Tatsuya Kanto, Tetsuo Takehara

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Incidence and risk factors of hepatocellular carcinoma in patients with hepatitis C who achieved a sustained virological response through direct‐acting antiviral agents among the w... by Hideki Hagiwara, Yoshiki Ito, Takashi Ohta, Yasutoshi Nozaki, Takayuki Iwamoto, Atsushi Hosui, Naoki Hiramatsu, Yuki Tahata, Ryotaro Sakamori, Hayato Hikita, Norio Hayashi

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CEACAM1 Is Associated With the Suppression of Natural Killer Cell Function in Patients With Chronic Hepatitis C by Takahiro Suda, Tomohide Tatsumi, Akira Nishio, Tadashi Kegasawa, Teppei Yoshioka, Ryoko Yamada, Kunimaro Furuta, Takahiro Kodama, Minoru Shigekawa, Hayato Hikita, Ryotaro Sakamori, Takasuke Fukuhara, Yoshiharu Matsuura, Tetsuo Takehara

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The Hepatitis B Virus Genotype Affects the Persistence of Viral Replication in Immunodeficient NOG Mice. by Yoshinobu Yokoyama, Takuya Miyagi, Hayato Hikita, Teppei Yoshioka, Kaori Mukai, Takatoshi Nawa, Ryotaro Sakamori, Kazuyoshi Ohkawa, Naoki Hiramatsu, Takeshi Takahashi, Hiroshi Suemizu, Akihide Ryo, Tomohide Tatsumi, Tetsuo Takehara

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Serum amyloid P component and pro-platelet basic protein in extracellular vesicles or serum are novel markers of liver fibrosis in chronic hepatitis C patients. by Kumiko Shirai, Hayato Hikita, Sadatsugu Sakane, Ryohei Narumi, Jun Adachi, Akira Doi, Satoshi Tanaka, Yuki Tahata, Ryoko Yamada, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Eiji Mita, Takeshi Tomonaga, Tetsuo Takehara

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Activation of p53 After Irradiation Impairs the Regenerative Capacity of the Mouse Liver by Makiko Urabe, Hayato Hikita, Yoshinobu Saito, Shinnosuke Kudo, Kenji Fukumoto, Naoki Mizutani, Yuta Myojin, Akira Doi, Katsuhiko Sato, Sadatsugu Sakane, Yuki Makino, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara

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White Adipose Tissue Autophagy and Adipose-Liver Crosstalk Exacerbate Nonalcoholic Fatty Liver Disease in MiceSummary by Sadatsugu Sakane, Hayato Hikita, Kumiko Shirai, Yuta Myojin, Youichi Sasaki, Shinnosuke Kudo, Kenji Fukumoto, Naoki Mizutani, Yuki Tahata, Yuki Makino, Ryoko Yamada, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara

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Persistent hepatocyte apoptosis promotes tumorigenesis from diethylnitrosamine-transformed hepatocytes through increased oxidative stress, independent of compensatory liver regener... by Yasutoshi Nozaki, Hayato Hikita, Satoshi Tanaka, Kenji Fukumoto, Makiko Urabe, Katsuhiko Sato, Yuta Myojin, Akira Doi, Kazuhiro Murai, Sadatsugu Sakane, Yoshinobu Saito, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara

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Hyperglycemia enhances pancreatic cancer progression accompanied by elevations in phosphorylated STAT3 and MYC levels. by Katsuhiko Sato, Hayato Hikita, Yuta Myojin, Kenji Fukumoto, Kazuhiro Murai, Sadatsugu Sakane, Takeshi Tamura, Takuo Yamai, Yasutoshi Nozaki, Teppei Yoshioka, Takahiro Kodama, Minoru Shigekawa, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara

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Folate receptor 1 is a stemness trait-associated diagnostic and prognostic marker for hepatocellular carcinoma by Yuto Shiode, Takahiro Kodama, Yu Sato, Ryo Takahashi, Takayuki Matsumae, Kumiko Shirai, Akira Doi, Yuki Tahata, Hayato Hikita, Tomohide Tatsumi, Moto Fukai, Akinobu Taketomi, Mathuros Ruchirawat, Xin Wei Wang, Tetsuo Takehara

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Pre-existing minor variants with NS5A L31M/V-Y93H double substitution are closely linked to virologic failure with asunaprevir plus daclatasvir treatment for genotype 1b hepatitis... by Naoki Morishita, Ryotaro Sakamori, Tomomi Yamada, Yugo Kai, Yuki Tahata, Ayako Urabe, Ryoko Yamada, Takahiro Kodama, Hayato Hikita, Yoshinori Doi, Shinji Tamura, Hideki Hagiwara, Yasuharu Imai, Sadaharu Iio, Tomohide Tatsumi, Tetsuo Takehara

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Capsid Allosteric Modulators Enhance the Innate Immune Response in Hepatitis B Virus–Infected Hepatocytes During Interferon Administration by Keisuke Fukutomi, Hayato Hikita, Kazuhiro Murai, Tasuku Nakabori, Akiyoshi Shimoda, Makoto Fukuoka, Takuo Yamai, Yuichiro Higuchi, Kei Miyakawa, Hiroshi Suemizu, Akihide Ryo, Ryoko Yamada, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara

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Regnase-1 downregulation promotes pancreatic cancer through myeloid-derived suppressor cell-mediated evasion of anticancer immunity by Junya Okabe, Takahiro Kodama, Yu Sato, Satoshi Shigeno, Takayuki Matsumae, Kazuma Daiku, Katsuhiko Sato, Teppei Yoshioka, Minoru Shigekawa, Masaya Higashiguchi, Shogo Kobayashi, Hayato Hikita, Tomohide Tatsumi, Toru Okamoto, Takashi Satoh, Hidetoshi Eguchi, Shizuo Akira, Tetsuo Takehara

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STAT3 is Activated by CTGF-mediated Tumor-stroma Cross Talk to Promote HCC ProgressionSummary by Yuki Makino, Hayato Hikita, Seiya Kato, Masaya Sugiyama, Minoru Shigekawa, Tatsuya Sakamoto, Yoichi Sasaki, Kazuhiro Murai, Sadatsugu Sakane, Takahiro Kodama, Ryotaro Sakamori, Shogo Kobayashi, Hidetoshi Eguchi, Nobuyuki Takemura, Norihiro Kokudo, Hideki Yokoi, Masashi Mukoyama, Tomohide Tatsumi, Tetsuo Takehara

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Forkhead Box M1 Transcription Factor Drives Liver Inflammation Linking to Hepatocarcinogenesis in MiceSummary by Tomohide Kurahashi, Yuichi Yoshida, Satoshi Ogura, Mayumi Egawa, Kunimaro Furuta, Hayato Hikita, Takahiro Kodama, Ryotaro Sakamori, Shinichi Kiso, Yoshihiro Kamada, I-Ching Wang, Hidetoshi Eguchi, Eiichi Morii, Yuichiro Doki, Masaki Mori, Vladimir V. Kalinichenko, Tomohide Tatsumi, Tetsuo Takehara

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