Opportunities at the Interface of Network Science and Metabolic Modeling by Varshit Dusad, Denise Thiel, Mauricio Barahona, Hector C. Keun, Hector C. Keun, Diego A. Oyarzún, Diego A. Oyarzún

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Predictive modelling using pathway scores: robustness and significance of pathway collections by Marcelo P. Segura-Lepe, Hector C. Keun, Timothy M. D. Ebbels

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The potential and challenges of targeting MTAP-negative cancers beyond synthetic lethality by Chandler Bray, Cristina Balcells, Iain A. McNeish, Hector C. Keun

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Editorial: Metabolomics and the exposome by Alexandros P. Siskos, Hector C. Keun, Benedikt Warth, Rachel S. Kelly, Lea Maitre

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β-Hydroxybutyrate Oxidation Promotes the Accumulation of Immunometabolites in Activated Microglia Cells by Adrian Benito, Nabil Hajji, Kevin O’Neill, Hector C. Keun, Nelofer Syed

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Altered Metabolic Profiles Associate with Toxicity in SOD1G93A Astrocyte-Neuron Co-Cultures by Gabriel N. Valbuena, Massimo Tortarolo, Caterina Bendotti, Lavinia Cantoni, Hector C. Keun

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Intracellular <i>Staphylococcus aureus</i> Elicits the Production of Host Very Long-Chain Saturated Fatty Acids with Antimicrobial Activity by Natalia Bravo-Santano, James K. Ellis, Yolanda Calle, Hector C. Keun, Volker Behrends, Michal Letek

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Intracellular <named-content content-type="genus-species">Staphylococcus aureus</named-content> Modulates Host Central Carbon Metabolism To Activate Autophagy by Natalia Bravo-Santano, James K. Ellis, Luis M. Mateos, Yolanda Calle, Hector C. Keun, Volker Behrends, Michal Letek

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Metabonomic Analysis of Water Extracts from Different Angelica Roots by 1H-Nuclear Magnetic Resonance Spectroscopy by Pui Hei Chan, Wendy L. Zhang, Chung-Ho Lau, Chi Yuen Cheung, Hector C. Keun, Karl W. K. Tsim, Henry Lam

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Consensus-phenotype integration of transcriptomic and metabolomic data implies a role for metabolism in the chemosensitivity of tumour cells. by Rachel Cavill, Atanas Kamburov, James K Ellis, Toby J Athersuch, Marcus S C Blagrove, Ralf Herwig, Timothy M D Ebbels, Hector C Keun

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T cell inhibitory mechanisms in a model of aggressive Non-Hodgkin's Lymphoma by Tamara Hilmenyuk, Carla A. Ruckstuhl, Michael Hayoz, Christian Berchtold, Jean-Marc Nuoffer, Shyam Solanki, Hector C. Keun, Paul A. Beavis, Carsten Riether, Adrian F. Ochsenbein

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Pharmacological depletion of RNA splicing factor RBM39 by indisulam synergizes with PARP inhibitors in high-grade serous ovarian carcinoma by Yuewei Xu, Sarah Spear, Yurui Ma, Marc P. Lorentzen, Michael Gruet, Flora McKinney, Yitao Xu, Chiharu Wickremesinghe, Madelen R. Shepherd, Iain McNeish, Hector C. Keun, Anke Nijhuis

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Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and Burkitt lymphoma by Richard A. Noble, Natalie Bell, Helen Blair, Arti Sikka, Huw Thomas, Nicole Phillips, Sirintra Nakjang, Satomi Miwa, Rachel Crossland, Vikki Rand, Despina Televantou, Anna Long, Hector C. Keun, Chris M. Bacon, Simon Bomken, Susan E. Critchlow, Stephen R. Wedge

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Associations of four biological age markers with child development: A multi-omic analysis in the European HELIX cohort by Oliver Robinson, ChungHo E Lau, Sungyeon Joo, Sandra Andrusaityte, Eva Borras, Paula de Prado-Bert, Lida Chatzi, Hector C Keun, Regina Grazuleviciene, Kristine B Gutzkow, Lea Maitre, Dries S Martens, Eduard Sabido, Valérie Siroux, Jose Urquiza, Marina Vafeiadi, John Wright, Tim S Nawrot, Mariona Bustamante, Martine Vrijheid

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Indisulam targets RNA splicing and metabolism to serve as a therapeutic strategy for high-risk neuroblastoma by Anke Nijhuis, Arti Sikka, Orli Yogev, Lili Herendi, Cristina Balcells, Yurui Ma, Evon Poon, Clare Eckold, Gabriel N. Valbuena, Yuewei Xu, Yusong Liu, Barbara Martins da Costa, Michael Gruet, Chiharu Wickremesinghe, Adrian Benito, Holger Kramer, Alex Montoya, David Carling, Elizabeth J. Want, Yann Jamin, Louis Chesler, Hector C. Keun

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Determinants of the urinary and serum metabolome in children from six European populations by Chung-Ho E. Lau, Alexandros P. Siskos, Léa Maitre, Oliver Robinson, Toby J. Athersuch, Elizabeth J. Want, Jose Urquiza, Maribel Casas, Marina Vafeiadi, Theano Roumeliotaki, Rosemary R. C. McEachan, Rafaq Azad, Line S. Haug, Helle M. Meltzer, Sandra Andrusaityte, Inga Petraviciene, Regina Grazuleviciene, Cathrine Thomsen, John Wright, Remy Slama, Leda Chatzi, Martine Vrijheid, Hector C. Keun, Muireann Coen

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Variability of multi-omics profiles in a population-based child cohort by Marta Gallego-Paüls, Carles Hernández-Ferrer, Mariona Bustamante, Xavier Basagaña, Jose Barrera-Gómez, Chung-Ho E. Lau, Alexandros P. Siskos, Marta Vives-Usano, Carlos Ruiz-Arenas, John Wright, Remy Slama, Barbara Heude, Maribel Casas, Regina Grazuleviciene, Leda Chatzi, Eva Borràs, Eduard Sabidó, Ángel Carracedo, Xavier Estivill, Jose Urquiza, Muireann Coen, Hector C. Keun, Juan R. González, Martine Vrijheid, Léa Maitre

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Multi-omics architecture of childhood obesity and metabolic dysfunction uncovers biological pathways and prenatal determinants by Nikos Stratakis, Augusto Anguita-Ruiz, Lorenzo Fabbri, Léa Maitre, Juan R. González, Sandra Andrusaityte, Xavier Basagaña, Eva Borràs, Hector C. Keun, Lida Chatzi, David V. Conti, Jesse Goodrich, Regina Grazuleviciene, Line Småstuen Haug, Barbara Heude, Wen Lun Yuan, Rosemary McEachan, Mark Nieuwenhuijsen, Eduard Sabidó, Rémy Slama, Cathrine Thomsen, Jose Urquiza, Theano Roumeliotaki, Marina Vafeiadi, John Wright, Mariona Bustamante, Martine Vrijheid

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The early-life exposome and epigenetic age acceleration in children by Paula de Prado-Bert, Carlos Ruiz-Arenas, Marta Vives-Usano, Sandra Andrusaityte, Solène Cadiou, Ángel Carracedo, Maribel Casas, Leda Chatzi, Payam Dadvand, Juan R. González, Regina Grazuleviciene, Kristine B. Gutzkow, Line S. Haug, Carles Hernandez-Ferrer, Hector C. Keun, Johanna Lepeule, Léa Maitre, Rosie McEachan, Mark J. Nieuwenhuijsen, Dolors Pelegrí, Oliver Robinson, Rémy Slama, Marina Vafeiadi, Jordi Sunyer, Martine Vrijheid, Mariona Bustamante

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In utero and childhood exposure to tobacco smoke and multi-layer molecular signatures in children by Marta Vives-Usano, Carles Hernandez-Ferrer, Léa Maitre, Carlos Ruiz-Arenas, Sandra Andrusaityte, Eva Borràs, Ángel Carracedo, Maribel Casas, Leda Chatzi, Muireann Coen, Xavier Estivill, Juan R. González, Regina Grazuleviciene, Kristine B. Gutzkow, Hector C. Keun, Chung-Ho E. Lau, Solène Cadiou, Johanna Lepeule, Dan Mason, Inés Quintela, Oliver Robinson, Eduard Sabidó, Gillian Santorelli, Per E. Schwarze, Alexandros P. Siskos, Rémy Slama, Marina Vafeiadi, Eulàlia Martí, Martine Vrijheid, Mariona Bustamante

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