A pilot phase I dose finding safety study of the thrombopoietin-receptor agonist, eltrombopag, in patients with myelodysplastic syndrome treated with azacitidine. by Svensson, T, Chowdhury, O, Garelius, H, Lorenz, F, Saft, L, Jacobsen, SE, Hellström-Lindberg, E, Cherif, H

Clonal heterogeneity in the 5q- syndrome: p53 expressing progenitors prevail during lenalidomide treatment and expand at disease progression. by Jädersten, M, Saft, L, Pellagatti, A, Göhring, G, Wainscoat, J, Boultwood, J, Porwit, A, Schlegelberger, B, Hellström-Lindberg, E

Perturbed hematopoietic stem and progenitor cell hierarchy in myelodysplastic syndromes patients with monosomy 7 as the sole cytogenetic abnormality. by Dimitriou, M, Woll, P, Mortera-Blanco, T, Karimi, M, Wedge, D, Doolittle, H, Douagi, I, Papaemmanuil, E, Jacobsen, S, Hellström-Lindberg, E

Del(5q) Myelodysplastic Stem Cells Exhibit Their Clonal Advantage Via Increased Adhesion to the Microenvironment by Scharenberg, C, Giai, V, Pellagatti, A, Saft, L, Karlsson, G, Jansson, M, Forsblom, L, Jadersten, M, Karlsson, S, Boultwood, J, Hellstrom-Lindberg, E

Deregulated Gene Expression Pathways in Myelodysplastic Syndrome Hematopoietic Stem Cells by Pellagatti, A, Cazzola, M, Giagounidis, A, Perry, J, Malcovati, L, Della Porta, MG, Jadersten, M, Killick, S, Verma, A, Hellstrom-Lindberg, E, Wainscoat, J, Boultwood, J

Identification of Prognostic Markers by Gene Expression Profiling In Myelodysplastic Syndrome Hematopoietic Stem Cells by Pellagatti, A, Cazzola, M, Giagounidis, A, Perry, J, Malcovati, L, Della Porta, MG, Jadersten, M, Killick, S, Vyas, P, Hellstrom-Lindberg, E, Boultwood, J, Wainscoat, J

Haploinsufficiency of RPS14 in 5q- syndrome is associated with deregulation of ribosomal- and translation-related genes (British Journal of Haematology (2008) 142, (57-64)) by Pellagatti, A, Hellström-Lindberg, E, Giagounidis, A, Perry, J, Malcovati, L, Della Porta, MG, Jädersten, M, Killick, S, Fidler, C, Cazzola, M, Wainscoat, J, Boultwood, J

Marked down-regulation of nucleophosmin-1 is associated with advanced del(5q) myelodysplastic syndrome. by Pellagatti, A, Cazzola, M, Giagounidis, A, Perry, J, Malcovati, L, Della Porta, MG, Jädersten, M, Killick, S, Vyas, P, Hellström-Lindberg, E, Wainscoat, J, Boultwood, J

Haploinsufficiency of RPS14 in 5q- syndrome is associated with deregulation of ribosomal- and translation-related genes. by Pellagatti, A, Hellström-Lindberg, E, Giagounidis, A, Perry, J, Malcovati, L, Della Porta, MG, Jädersten, M, Killick, S, Fidler, C, Cazzola, M, Wainscoat, J, Boultwood, J

Marked down-regulation of nucleophosmin-1 is associated with advanced del(5q) myelodysplastic syndrome by Pellagatti, A, Cazzola, M, Giagounidis, A, Perry, J, Malcovati, L, Della Porta, MG, Jädersten, M, Killick, S, Vyas, P, Hellström-Lindberg, E, Wainscoat, J, Boultwood, J

Mutation Analysis of TET2 Reveals the Clonal Nature of Refractory Anemia with Ring Sideroblasts by Malcovati, L, Brisci, A, Galli, A, Bruno, F, Travaglino, E, Pellagatti, A, Della Porta, MG, Ferrari, M, Boultwood, J, Cremonesi, L, Hellstrom-Lindberg, E, Cazzola, M

Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q- syndrome patients. by Pellagatti, A, Jädersten, M, Forsblom, A, Cattan, H, Christensson, B, Emanuelsson, E, Merup, M, Nilsson, L, Samuelsson, J, Sander, B, Wainscoat, J, Boultwood, J, Hellström-Lindberg, E

NEW INSIGHTS INTO THE BIOLOGY OF REFRACTORY ANEMIA WITH RING SIDEROBLASTS (RARS) AND IDENTIFICATION OF ERYTHROID G-CSF TARGETS BY GENE EXPRESSION PROFILING by Nikpour, M, Pellagatti, A, Liu, A, Karimi, M, Malcovati, L, Forsblom, A, Gogvadze, V, Wainscoat, J, Cazzola, M, Zhivotovsky, B, Grandien, A, Boultwood, J, Hellstrom-Lindberg, E

Gene expression profiling of CD34+ cells in patients with the 5q- syndrome. by Boultwood, J, Pellagatti, A, Cattan, H, Lawrie, C, Giagounidis, A, Malcovati, L, Della Porta, MG, Jädersten, M, Killick, S, Fidler, C, Cazzola, M, Hellström-Lindberg, E, Wainscoat, J

YI1 Gene expression profiling of day 7 erythroblasts from refractory anemia with ringed sideroblasts (RARS) and microarray-based identification of erythroid granulocyte-CSF (G-CSF)... by Nikpour, M, Pellagatti, A, Liu, A, Karimi, M, Malcovati, L, Forsblom, A, Gogvadze, V, Wainscoat, J, Cazzola, M, Zhivotovsky, B, Grandien, A, Boultwood, J, Hellström-Lindberg, E

Deregulated gene expression pathways in myelodysplastic syndrome hematopoietic stem cells. by Pellagatti, A, Cazzola, M, Giagounidis, A, Perry, J, Malcovati, L, Della Porta, MG, Jädersten, M, Killick, S, Verma, A, Norbury, C, Hellström-Lindberg, E, Wainscoat, J, Boultwood, J

Gene expression profiling of erythroblasts from refractory anaemia with ring sideroblasts (RARS) and effects of G-CSF. by Nikpour, M, Pellagatti, A, Liu, A, Karimi, M, Malcovati, L, Gogvadze, V, Forsblom, A, Wainscoat, J, Cazzola, M, Zhivotovsky, B, Grandien, A, Boultwood, J, Hellström-Lindberg, E

Lenalidomide up-regulates SPARC and inhibits in vitro growth of the malignant clone in myelodysplastic syndrome patients with 5q deletion. by Pellagatti, A, Jadersten, M, Forsblom, A, Cattan, H, Christensson, B, Emanuelsson, E, Merup, M, Nilsson, L, Samuelsson, J, Sander, B, Wainscoat, J, Boultwood, J, Hellstrom-Lindberg, E

Gene expression profiling of day 7 erythroblasts from refractory anemia with ringed sideroblasts (RARS) and microarray-based identification of erythroid granulocyte-CSF (G-CSF) tar... by Nikpour, M, Pellagatti, A, Liu, A, Karimi, M, Malcovati, L, Forsblom, A, Gogvadze, V, Wainscoat, J, Cazzola, M, Zhivotovsky, B, Grandien, A, Boultwood, J, Hellstrom-Lindberg, E

Marked downregulation of the granulopoiesis regulator LEF1 is associated with disease progression in the myelodysplastic syndromes. by Pellagatti, A, Marafioti, T, Paterson, J, Malcovati, L, Della Porta, MG, Jädersten, M, Pushkaran, B, George, T, Arber, D, Killick, S, Giagounidis, A, Hellström-Lindberg, E, Cazzola, M, Wainscoat, J, Boultwood, J