Opioids and Their Receptors: Present and Emerging Concepts in Opioid Drug Discovery by Mariana Spetea, Helmut Schmidhammer

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Recent Chemical and Pharmacological Developments on 14-Oxygenated-<i>N</i>-methylmorphinan-6-ones by Mariana Spetea, Helmut Schmidhammer

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Unveiling 7‑Hydroxymitragynine as the Key Active Metabolite of Mitragynine and the Promise for Creating Novel Pain Relievers by Mariana Spetea, Helmut Schmidhammer

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Development of Diphenethylamines as Selective Kappa Opioid Receptor Ligands and Their Pharmacological Activities by Helmut Schmidhammer, Filippo Erli, Elena Guerrieri, Mariana Spetea

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Mechanistic Characterization of the Pharmacological Profile of HS-731, a Peripherally Acting Opioid Analgesic, at the µ-, δ-, κ-Opioid and Nociceptin Receptors by Kristina Puls, Helmut Schmidhammer, Gerhard Wolber, Mariana Spetea

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Peripheralization Strategies Applied to Morphinans and Implications for Improved Treatment of Pain by Helmut Schmidhammer, Mahmoud Al-Khrasani, Susanna Fürst, Mariana Spetea

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In vitro and in vivo Pharmacological Activities of 14-O-Phenylpropyloxymorphone, a Potent Mixed Mu/Delta/Kappa-Opioid Receptor Agonist With Reduced Constipation in Mice by Roberta Lattanzi, Silvia Rief, Helmut Schmidhammer, Lucia Negri, Mariana Spetea

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On the Role of Peripheral Sensory and Gut Mu Opioid Receptors: Peripheral Analgesia and Tolerance by Susanna Fürst, Zoltán S. Zádori, Ferenc Zádor, Kornél Király, Mihály Balogh, Szilvia B. László, Barbara Hutka, Amir Mohammadzadeh, Chiara Calabrese, Anna Rita Galambos, Pál Riba, Patrizia Romualdi, Sándor Benyhe, Júlia Timár, Helmut Schmidhammer, Mariana Spetea, Mahmoud Al-Khrasani

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