Inclusion and response criteria for clinical trials in relapsed/refractory acute lymphoblastic leukemia and usefulness of historical control trials by Nicola Gökbuget, Herve Dombret, Renato Bassan, Martha Wadleigh, Michael Doubek, Josep Ribera

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Successful tyrosine kinase inhibitor therapy in a refractory B-cell precursor acute lymphoblastic leukemia with EBF1-PDGFRB fusion by Etienne Lengline, Kheïra Beldjord, Hervé Dombret, Jean Soulier, Nicolas Boissel, Emmanuelle Clappier

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Early onset hypercholesterolemia induced by the 2nd-generation tyrosine kinase inhibitor nilotinib in patients with chronic phase-chronic myeloid leukemia by Delphine Rea, Tristan Mirault, Thomas Cluzeau, Jean-François Gautier, François Guilhot, Hervé Dombret, Emmanuel Messas

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L-asparaginase for adult CD20 positive B-cell precursor acute lymphoblastic leukemia by Sébastien Maury, Françoise Huguet, Norbert Ifrah, Hervé Dombret, Marie-Christine Béné, for the Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL)

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Prophylactic and therapeutic antileukemic effects induced by the AAC-11-derived Peptide RT53 by Justine Habault, Anna Kaci, Ewa Pasquereau-Kotula, Claire Fraser, Christine Chomienne, Hervé Dombret, Thorsten Braun, Marika Pla, Jean-Luc Poyet

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Prevention, recognition, and management of adverse events associated with gemtuzumab ozogamicin use in acute myeloid leukemia by Jorge E. Cortes, Marcos de Lima, Hervé Dombret, Elihu H. Estey, Sergio A. Giralt, Pau Montesinos, Christoph Röllig, Adriano Venditti, Eunice S. Wang

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Impact of post-remission therapy in patients aged 65–70 years with de novo acute myeloid leukemia: a comparison of two concomitant randomized ALFA trials with overlapping age inclu... by Raphael Itzykson, Claude Gardin, Cécile Pautas, Xavier Thomas, Pascal Turlure, Emmanuel Raffoux, Christine Terré, Pierre Fenaux, Sylvie Castaigne, Hervé Dombret, Nicolas Boissel

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Prospective long-term minimal residual disease monitoring using RQ-PCR in RUNX1-RUNX1T1-positive acute myeloid leukemia: results of the French CBF-2006 trial by Christophe Willekens, Odile Blanchet, Aline Renneville, Pascale Cornillet-Lefebvre, Cécile Pautas, Romain Guieze, Norbert Ifrah, Hervé Dombret, Eric Jourdan, Claude Preudhomme, Nicolas Boissel

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S106: METABOLIC PLASTICITY REVEALS A TARGETABLE VULNERABILITY IN LEUKEMIA by Guillaume Andrieu, Mathieu Simonin, Aurélie Cabannes-Hamy, Etienne Lengliné, Ambroise Marçais, Marie-Emilie Dourthe, Alexandre Theron, Nicolas Boissel, Hervé Dombret, Philippe Rousselot, Olivier Hermine, Vahid Asnafi

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A phase I study of danusertib (PHA-739358) in adult patients with accelerated or blastic phase chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leu... by Gautam Borthakur, Herve Dombret, Philippe Schafhausen, Tim Henrik Brummendorf, Nicolas Boissel, Elias Jabbour, Mariangela Mariani, Laura Capolongo, Patrizia Carpinelli, Cristina Davite, Hagop Kantarjian, Jorge E. Cortes

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Daunorubicin and Its Active Metabolite Pharmacokinetic Profiles in Acute Myeloid Leukaemia Patients: A Pharmacokinetic Ancillary Study of the BIG-1 Trial by Guillaume Drevin, Marie Briet, Caroline Bazzoli, Emmanuel Gyan, Aline Schmidt, Hervé Dombret, Corentin Orvain, Aurelien Giltat, Christian Recher, Norbert Ifrah, Philippe Guardiola, Mathilde Hunault-Berger, Chadi Abbara

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Intensive induction is effective in selected octogenarian acute myeloid leukemia patients: prognostic significance of karyotype and selected molecular markers used in the European... by Meir Wetzler, Krzysztof Mrózek, Jessica Kohlschmidt, Hervé Dombret, Hartmut Döhner, Sylvain Pilorge, Utz Krug, Andrew J. Carroll, Richard A. Larson, Guido Marcucci, Wolfgang Hiddemann, Thomas Büchner, Clara D. Bloomfield

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An early thymic precursor phenotype predicts outcome exclusively in HOXA-overexpressing adult T-cell acute lymphoblastic leukemia: a Group for Research in Adult Acute Lymphoblastic... by Jonathan Bond, Tony Marchand, Aurore Touzart, Agata Cieslak, Amélie Trinquand, Laurent Sutton, Isabelle Radford-Weiss, Ludovic Lhermitte, Salvatore Spicuglia, Hervé Dombret, Elizabeth Macintyre, Norbert Ifrah, Jean-François Hamel, Vahid Asnafi

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Survival outcomes with oral azacitidine maintenance in patients with acute myeloid leukemia in remission by receipt of initial chemotherapy: subgroup analyses from the phase III QU... by Andrew H. Wei, Gail J. Roboz, Herve Dombret, Hartmut Dohner, Andre C. Schuh, Pau Montesinos, Dominik Selleslag, Sergey N. Bondarenko, Thomas Prebet, Yinzhi Lai, Barry Skikne, C.L. Beach, Farhad Ravandi

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Risk factors and decision criteria for intensive chemotherapy in older patients with acute myeloid leukemia by Jean-Valère Malfuson, Anne Etienne, Pascal Turlure, Thierry de Revel, Xavier Thomas, Nathalie Contentin, Christine Terré, Sophie Rigaudeau, Dominique Bordessoule, Norbert Vey, Claude Gardin, Hervé Dombret, for the Acute Leukemia French Association (ALFA)

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Clinical relevance of IDH1/2 mutant allele burden during follow-up in acute myeloid leukemia. A study by the French ALFA group by Yann Ferret, Nicolas Boissel, Nathalie Helevaut, Jordan Madic, Olivier Nibourel, Alice Marceau-Renaut, Maxime Bucci, Sandrine Geffroy, Karine Celli-Lebras, Sylvie Castaigne, Xavier Thomas, Christine Terré, Hervé Dombret, Claude Preudhomme, Aline Renneville

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A metabolic synthetic lethality of phosphoinositide 3-kinase-driven cancer by Guillaume P. Andrieu, Mathieu Simonin, Aurélie Cabannes-Hamy, Etienne Lengliné, Ambroise Marçais, Alexandre Théron, Grégoire Huré, Jérome Doss, Ivan Nemazanyy, Marie Émilie Dourthe, Nicolas Boissel, Hervé Dombret, Philippe Rousselot, Olivier Hermine, Vahid Asnafi

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Low level CpG island promoter methylation predicts a poor outcome in adult T-cell acute lymphoblastic leukemia by Aurore Touzart, Nicolas Boissel, Mohamed Belhocine, Charlotte Smith, Carlos Graux, Mehdi Latiri, Ludovic Lhermitte, Eve-Lyne Mathieu, Françoise Huguet, Laurence Lamant, Pierre Ferrier, Norbert Ifrah, Elizabeth Macintyre, Hervé Dombret, Vahid Asnafi, Salvatore Spicuglia

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Multi-target measurable residual disease assessed by error-corrected sequencing in patients with acute myeloid leukemia: An ALFA study by Pierre Hirsch, Jérôme Lambert, Maxime Bucci, Caroline Deswarte, Augustin Boudry, Juliette Lambert, Laurene Fenwarth, Jean-Baptiste Micol, Christine Terré, Karine Celli-Lebras, Xavier Thomas, Hervé Dombret, Nicolas Duployez, Claude Preudhomme, Raphael Itzykson, Francois Delhommeau

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Publisher Correction: Frugal alignment-free identification of FLT3-internal tandem duplications with FiLT3r by Augustin Boudry, Sasha Darmon, Nicolas Duployez, Martin Figeac, Sandrine Geffroy, Maxime Bucci, Karine Celli-Lebras, Matthieu Duchmann, Romane Joudinaud, Laurène Fenwarth, Olivier Nibourel, Laure Goursaud, Raphael Itzykson, Hervé Dombret, Mathilde Hunault, Claude Preudhomme, Mikaël Salson

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