Genetically Engineered T-Cells for Malignant Glioma: Overcoming the Barriers to Effective Immunotherapy by Pavlina Chuntova, Kira M. Downey, Bindu Hegde, Neil D. Almeida, Neil D. Almeida, Hideho Okada, Hideho Okada, Hideho Okada

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Lessons from Post-Immunotherapy Tumor Tissues in Clinical Trials: How Can We Fuel the Tumor Microenvironment in Gliomas? by Lan Hoc Phung, Takahide Nejo, Hideho Okada

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IFN-γ- and IL-17-producing CD8+ T (Tc17-1) cells in combination with poly-ICLC and peptide vaccine exhibit antiglioma activity by Takayuki Ohkuri, Akemi Kosaka, Hideho Okada, Maki Ikeura

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In vivo intracellular oxygen dynamics in murine brain glioma and immunotherapeutic response of cytotoxic T cells observed by fluorine-19 magnetic resonance imaging. by Jia Zhong, Masashi Sakaki, Hideho Okada, Eric T Ahrens

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843 Intra-cerebral spinal fluid vaccination to facilitate antigen-specific T-cell responses in the CNS tumors by Hideho Okada, Tiffany Chen, Akane Yamamichi, Naozumi Harada, Su Phyu, Akinari Kazuyoshi

Glioblastoma vaccines: past, present, and opportunities by Zujian Xiong, Itay Raphael, Michael Olin, Hideho Okada, Xuejun Li, Gary Kohanbash

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Correspondence on 'H3.3K27M mutation is not a suitable target for immunotherapy in HLA-A2+ patients with diffuse midline glioma' by Immisch et al by Lisa H Butterfield, Hideho Okada, Sabine Mueller, Zinal S Chheda, Bindu Hegde, Akane Yamamichi

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A Roadmap of CAR-T-Cell Therapy in Glioblastoma: Challenges and Future Perspectives by Megan Montoya, Marco Gallus, Su Phyu, Jeffrey Haegelin, John de Groot, Hideho Okada

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The evolution of alternative splicing in glioblastoma under therapy by Lin Wang, Karin Shamardani, Husam Babikir, Francisca Catalan, Takahide Nejo, Susan Chang, Joanna J. Phillips, Hideho Okada, Aaron A. Diaz

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Ultrasound frequency-controlled microbubble dynamics in brain vessels regulate the enrichment of inflammatory pathways in the blood-brain barrier by Yutong Guo, Hohyun Lee, Chulyong Kim, Christian Park, Akane Yamamichi, Pavlina Chuntova, Marco Gallus, Miguel O. Bernabeu, Hideho Okada, Hanjoong Jo, Costas Arvanitis

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EphA2 as a Glioma-Associated Antigen: A Novel Target for Glioma Vaccines by Manabu Hatano, Junichi Eguchi, Tomohide Tatsumi, Naruo Kuwashima, Jill E. Dusak, Michel S. Kinch, Ian F. Pollack, Ronald L. Hamilton, Walter J. Storkus, Hideho Okada

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The future of cancer immunotherapy for brain tumors: a collaborative workshop by Christine E. Brown, Samantha Bucktrout, Lisa H. Butterfield, Olga Futer, Evanthia Galanis, Adilia Hormigo, Michael Lim, Hideho Okada, Robert Prins, Sara Siebel Marr, Kirk Tanner

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Inhibition of Indoleamine-2,3-dioxygenase (IDO) in Glioblastoma Cells by Oncolytic Herpes Simplex Virus by Bonnie Reinhart, Lucia Mazzacurati, Adriana Forero, Chang-Sook Hong, Junichi Eguchi, Hideho Okada, Wendy Fellows, Ajay Niranjan, Justus B. Cohen, Joseph C. Glorioso, Paola Grandi

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Genetically stable poliovirus vectors activate dendritic cells and prime antitumor CD8 T cell immunity by Mubeen M. Mosaheb, Elena Y. Dobrikova, Michael C. Brown, Yuanfan Yang, Jana Cable, Hideho Okada, Smita K. Nair, Darell D. Bigner, David M. Ashley, Matthias Gromeier

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956 Glioma-neuronal circuit remodeling induces regional immunosuppression by Hideho Okada, Tiffany Chen, Takahide Nejo, Akane Yamamichi, Shawn L Hervey-Jumper, Su Phyu, Saritha Krishna, Christian Jimenez, Jacob S Young, Senthilnath Lakshmanachetty, Payal Watchmaker, Abrar Choudhury, David R Raleigh

Antigenic expression and spontaneous immune responses support the use of a selected peptide set from the IMA950 glioblastoma vaccine for immunotherapy of grade II and III glioma by Valérie Dutoit, Denis Migliorini, Giulia Ranzanici, Eliana Marinari, Valérie Widmer, Johannes Alexander Lobrinus, Shahan Momjian, Joseph Costello, Paul R. Walker, Hideho Okada, Toni Weinschenk, Christel Herold-Mende, Pierre-Yves Dietrich

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277 SynNotch-CAR T cells demonstrate potent anti-tumor efficacy in a preclinical immunocompetent mouse model for glioblastoma by Yuan Wang, Hideho Okada, Wendell Lim, Tiffany Chen, Takahide Nejo, Akane Yamamichi, Su Phyu, Senthilnath Lakshmanachetty, Payal Watchmaker, Milos Simic, Chanelle Shepherd, Jason Duecker, Olga Troyanskaya, Lia Cardarelli, Sachdev Sidhu

The immune suppressive microenvironment of human gliomas depends on the accumulation of bone marrow-derived macrophages in the center of the lesion by Laura Pinton, Elena Masetto, Marina Vettore, Samantha Solito, Sara Magri, Marta D’Andolfi, Paola Del Bianco, Giovanna Lollo, Jean-Pierre Benoit, Hideho Okada, Aaron Diaz, Alessandro Della Puppa, Susanna Mandruzzato

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Zika virus oncolytic activity requires CD8+ T cells and is boosted by immune checkpoint blockade by Sharmila Nair, Luciano Mazzoccoli, Arijita Jash, Jennifer Govero, Sachendra S. Bais, Tong Hu, Camila R. Fontes-Garfias, Chao Shan, Hideho Okada, Sujan Shresta, Jeremy N. Rich, Pei-Yong Shi, Michael S. Diamond, Milan G. Chheda

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144 Novel public and tumor-wide neoantigens arising from clonal aberrant splicing events drive tumor-specific T-cell responses across diverse cancer types by Gary Chan, Hideho Okada, Kaori Okada, Iñaki Etxeberría, Christopher A Klebanoff, Joseph Costello, Takahide Nejo, James Woo, Akane Yamamichi, Darwin Kwok, Chibo Hong, Aidan Du, Nicholas Stevers, Senthilnath Lakshmanachetty, Jangham Jung, Lee Chen, Marco Gallus, Emilio Ramos, Maggie Colton Cove, Arun Wiita