The Hygiene Hypothesis and New Perspectives—Current Challenges Meeting an Old Postulate by Holger Garn, Holger Garn, Daniel Piotr Potaczek, Petra Ina Pfefferle, Petra Ina Pfefferle, Petra Ina Pfefferle

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Editorial: The Immunological Implications of the Hygiene Hypothesis by Petra Ina Pfefferle, Idoia Postigo, Holger Garn

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The Hygiene Hypothesis – Learning From but Not Living in the Past by Petra I. Pfefferle, Petra I. Pfefferle, Petra I. Pfefferle, Corinna U. Keber, Corinna U. Keber, Corinna U. Keber, Robert M. Cohen, Holger Garn, Holger Garn

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Local and Systemic Production of Pro-Inflammatory Eicosanoids Is Inversely Related to Sensitization to Aeroallergens in Patients with Aspirin-Exacerbated Respiratory Disease by Daniel P. Potaczek, Gabriela Trąd, Marek Sanak, Holger Garn, Lucyna Mastalerz

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Extracellular Vesicles and Asthma—More Than Just a Co-Existence by Bilal Alashkar Alhamwe, Daniel P. Potaczek, Sarah Miethe, Fahd Alhamdan, Lukas Hintz, Arslan Magomedov, Holger Garn

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Schistosoma mansoni-mediated suppression of allergic airway inflammation requires patency and Foxp3+ Treg cells. by Laura E Layland, Kathrin Straubinger, Manuel Ritter, Eva Loffredo-Verde, Holger Garn, Tim Sparwasser, Clarissa Prazeres da Costa

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Human Lung Organoids—A Novel Experimental and Precision Medicine Approach by Laura Kühl, Pauline Graichen, Nele von Daacke, Anne Mende, Malgorzata Wygrecka, Daniel P. Potaczek, Sarah Miethe, Holger Garn

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Glutaredoxin 2 Reduces Asthma-Like Acute Airway Inflammation in Mice by Eva-Maria Hanschmann, Carsten Berndt, Christina Hecker, Holger Garn, W. Bertrams, Christopher H. Lillig, Christoph Hudemann, Christoph Hudemann

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A Gain-Of-Function Mutation in the Plcg2 Gene Protects Mice from Helicobacter felis-Induced Gastric MALT Lymphoma. by Jennifer Gossmann, Manfred Stolte, Michael Lohoff, Philipp Yu, Roland Moll, Florian Finkernagel, Holger Garn, Cornelia Brendel, Alwina Bittner, Andreas Neubauer, Minh Q Huynh

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IL-17 and TNF-α Are Key Mediators of Moraxella catarrhalis Triggered Exacerbation of Allergic Airway Inflammation by Safa Alnahas, Stefanie Hagner, Hartmann Raifer, Ayse Kilic, Georg Gasteiger, Reinier Mutters, Anne Hellhund, Immo Prinz, Olaf Pinkenburg, Alexander Visekruna, Holger Garn, Ulrich Steinhoff

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Differential Regulation of Interferon Signaling Pathways in CD4⁺ T Cells of the Low Type-2 Obesity-Associated Asthma Phenotype by Fahd Alhamdan, Leigh M. Marsh, Frauke Pedersen, Bilal Alashkar Alhamwe, Clemens Thölken, Petra Ina Pfefferle, Thomas Bahmer, Timm Greulich, Daniel P. Potaczek, Holger Garn

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Histone modifications and their role in epigenetics of atopy and allergic diseases by Bilal Alaskhar Alhamwe, Razi Khalaila, Johanna Wolf, Verena von Bülow, Hani Harb, Fahd Alhamdan, Charles S. Hii, Susan L. Prescott, Antonio Ferrante, Harald Renz, Holger Garn, Daniel P. Potaczek

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Side-Directed Release of Differential Extracellular Vesicle-associated microRNA Profiles from Bronchial Epithelial Cells of Healthy and Asthmatic Subjects by Viktoria E. M. Schindler, Fahd Alhamdan, Christian Preußer, Lukas Hintz, Bilal Alashkar Alhamwe, Andrea Nist, Thorsten Stiewe, Elke Pogge von Strandmann, Daniel P. Potaczek, Clemens Thölken, Holger Garn

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Timing of Blood Sample Processing Affects the Transcriptomic and Epigenomic Profiles in CD4⁺ T-cells of Atopic Subjects by Fahd Alhamdan, Kristina Laubhahn, Christine Happle, Anika Habener, Adan C. Jirmo, Clemens Thölken, Raffaele Conca, Ho-Ryun Chung, Gesine Hansen, Daniel P. Potaczek, Bianca Schaub, Ruth Grychtol, Holger Garn

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A GATA3-specific DNAzyme attenuates sputum eosinophilia in eosinophilic COPD patients: a feasibility randomized clinical trial by Timm Greulich, Jens M. Hohlfeld, Petra Neuser, Katrin Lueer, Andreas Klemmer, Carmen Schade-Brittinger, Susanne Harnisch, Holger Garn, Harald Renz, Ursula Homburg, Jonas Renz, Anne Kirsten, Frauke Pedersen, Meike Müller, Claus F. Vogelmeier, Henrik Watz

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Reciprocal regulation of the Il9 locus by counteracting activities of transcription factors IRF1 and IRF4 by Lucia Campos Carrascosa, Matthias Klein, Yohko Kitagawa, Christina Lückel, Federico Marini, Anika König, Anna Guralnik, Hartmann Raifer, Stefanie Hagner-Benes, Diana Rädler, Andreas Böck, Cholho Kang, Michael Lohoff, Holger Garn, Bianca Schaub, Friederike Berberich-Siebelt, Shimon Sakaguchi, Tobias Bopp, Magdalena Huber

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Perinatal and Early-Life Nutrition, Epigenetics, and Allergy by Nathalie Acevedo, Bilal Alashkar Alhamwe, Luis Caraballo, Mei Ding, Antonio Ferrante, Holger Garn, Johan Garssen, Charles S. Hii, James Irvine, Kevin Llinás-Caballero, Juan Felipe López, Sarah Miethe, Khalida Perveen, Elke Pogge von Strandmann, Milena Sokolowska, Daniel P. Potaczek, Betty C. A. M. van Esch

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Decreased Histone Acetylation Levels at Th1 and Regulatory Loci after Induction of Food Allergy by Bilal Alashkar Alhamwe, Laura A. P. M. Meulenbroek, Désirée H. Veening-Griffioen, Tjalling M. D. Wehkamp, Fahd Alhamdan, Sarah Miethe, Hani Harb, Astrid Hogenkamp, Léon M. J. Knippels, Elke Pogge von Strandmann, Harald Renz, Johan Garssen, Betty C. A. M. van Esch, Holger Garn, Daniel P. Potaczek, Machteld M. Tiemessen

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