Ligand-mediated and tertiary interactions cooperatively stabilize the P1 region in the guanine-sensing riboswitch. by Christian A Hanke, Holger Gohlke

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DrugScorePPI knowledge-based potentials used as scoring and objective function in protein-protein docking. by Dennis M Krüger, José Ignacio Garzón, Pablo Chacón, Holger Gohlke

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Diagnostic workup of suspected hereditary cholestasis in adults: a case report by Carola Dröge, Tobias Götze, Annika Behrendt, Holger Gohlke, Verena Keitel

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40 Years of Research on Polybrominated Diphenyl Ethers (PBDEs)—A Historical Overview and Newest Data of a Promising Anticancer Drug by Laura Schmitt, Ilka Hinxlage, Pablo A. Cea, Holger Gohlke, Sebastian Wesselborg

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Foamy Viruses, Bet, and APOBEC3 Restriction by Ananda Ayyappan Jaguva Vasudevan, Daniel Becker, Tom Luedde, Holger Gohlke, Carsten Münk

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Physiological, Biochemical, and Structural Bioinformatic Analysis of the Multiple Inositol Dehydrogenases from Corynebacterium glutamicum by Paul Ramp, Christopher Pfleger, Jonas Dittrich, Christina Mack, Holger Gohlke, Michael Bott

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Critical assessment of structure-based approaches to improve protein resistance in aqueous ionic liquids by enzyme-wide saturation mutagenesis by Till El Harrar, Mehdi D. Davari, Karl-Erich Jaeger, Ulrich Schwaneberg, Holger Gohlke

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Resolving hot spots in the C-terminal dimerization domain that determine the stability of the molecular chaperone Hsp90. by Emanuele Ciglia, Janina Vergin, Sven Reimann, Sander H J Smits, Lutz Schmitt, Georg Groth, Holger Gohlke

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Molecular Mechanisms Underlying Medium-Chain Free Fatty Acid-Regulated Activity of the Phospholipase PlaF from Pseudomonas aeruginosa by Rocco Gentile, Matea Modric, Björn Thiele, Karl-Erich Jaeger, Filip Kovacic, Stephan Schott-Verdugo, Holger Gohlke

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Vasor: Accurate prediction of variant effects for amino acid substitutions in multidrug resistance protein 3 by Annika Behrendt, Pegah Golchin, Filip König, Daniel Mulnaes, Amelie Stalke, Carola Dröge, Verena Keitel, Holger Gohlke

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Structure and dimerization properties of the plant-specific copper chaperone CCH by Dominik Dluhosch, Lisa Sophie Kersten, Stephan Schott-Verdugo, Claudia Hoppen, Melanie Schwarten, Dieter Willbold, Holger Gohlke, Georg Groth

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Aplospojaveedins A–C, unusual sulfur-containing alkaloids produced by the endophytic fungus Aplosporella javeedii using OSMAC strategy by Ying Gao, Ying Gao, Marian Frank, Nicole Teusch, Dennis Woschko, Christoph Janiak, Attila Mándi, Tibor Kurtán, Rudolf Hartmann, Katja Schiedlauske, Lasse van Geelen, Rainer Kalscheuer, Jesko Kaiser, Christoph G. W. Gertzen, Holger Gohlke, Holger Gohlke, Bin-Gui Wang, Peter Proksch, Zhen Liu

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The ISG15-Protease USP18 Is a Pleiotropic Enhancer of HIV-1 Replication by Chaohui Lin, Edmund Osei Kuffour, Taolan Li, Christoph G. W. Gertzen, Jesko Kaiser, Tom Luedde, Renate König, Holger Gohlke, Carsten Münk

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Interaction of Ochratoxin A and Its Thermal Degradation Product 2′R-Ochratoxin A with Human Serum Albumin by Franziska Sueck, Miklós Poór, Zelma Faisal, Christoph G. W. Gertzen, Benedikt Cramer, Beáta Lemli, Sándor Kunsági-Máté, Holger Gohlke, Hans-Ulrich Humpf

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A MademoiseLLE domain binding platform links the key RNA transporter to endosomes. by Senthil-Kumar Devan, Stephan Schott-Verdugo, Kira Müntjes, Lilli Bismar, Jens Reiners, Eymen Hachani, Lutz Schmitt, Astrid Höppner, Sander Hj Smits, Holger Gohlke, Michael Feldbrügge

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Novel 4-alkoxy Meriolin Congeners Potently Induce Apoptosis in Leukemia and Lymphoma Cells by Karina S. Krings, Tobias R. Wassenberg, Pablo Cea-Medina, Laura Schmitt, Ilka Lechtenberg, Tanya R. Llewellyn, Nan Qin, Holger Gohlke, Sebastian Wesselborg, Thomas J. J. Müller

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Structural, mechanistic, and physiological insights into phospholipase A-mediated membrane phospholipid degradation in Pseudomonas aeruginosa by Florian Bleffert, Joachim Granzin, Muttalip Caliskan, Stephan N Schott-Verdugo, Meike Siebers, Björn Thiele, Laurence Rahme, Sebastian Felgner, Peter Dörmann, Holger Gohlke, Renu Batra-Safferling, Karl-Erich Jaeger, Filip Kovacic

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Total Synthesis of the Antimycobacterial Natural Product Chlorflavonin and Analogs via a Late-Stage Ruthenium(II)-Catalyzed <i>ortho</i>-C(sp²)-H-Hydroxylation by Alexander Berger, Talea Knak, Anna-Lene Kiffe-Delf, Korana Mudrovcic, Vinayak Singh, Mathew Njoroge, Bjoern B. Burckhardt, Mohanraj Gopalswamy, Beate Lungerich, Lutz Ackermann, Holger Gohlke, Kelly Chibale, Rainer Kalscheuer, Thomas Kurz

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Novel meriolin derivatives potently inhibit cell cycle progression and transcription in leukemia and lymphoma cells via inhibition of cyclin-dependent kinases (CDKs) by Laura Schmitt, Julia Hoppe, Pablo Cea-Medina, Peter-Martin Bruch, Karina S. Krings, Ilka Lechtenberg, Daniel Drießen, Christoph Peter, Sanil Bhatia, Sascha Dietrich, Björn Stork, Gerhard Fritz, Holger Gohlke, Thomas J. J. Müller, Sebastian Wesselborg

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Biophysical and pharmacokinetic characterization of a small-molecule inhibitor of RUNX1/ETO tetramerization with anti-leukemic effects by Mohanraj Gopalswamy, Tobias Kroeger, David Bickel, Benedikt Frieg, Shahina Akter, Stephan Schott-Verdugo, Aldino Viegas, Thomas Pauly, Manuela Mayer, Julia Przibilla, Jens Reiners, Luitgard Nagel-Steger, Sander H. J. Smits, Georg Groth, Manuel Etzkorn, Holger Gohlke

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