HIV-1 Escape from an HLA-B*13-Restricted Gag Epitope Affects the Gag-Pol Frameshift Stem-loop and Reduces Viral Fitness by Prado, J, Honeyborne, I, Goulder, P

Functional consequences of human immunodeficiency virus escape from an HLA-B*13-restricted CD8+ T-cell epitope in p1 Gag protein. by Prado, J, Honeyborne, I, Brierley, I, Puertas, M, Martinez-Picado, J, Goulder, P

P09-18. Cw 0303/0304 HIV specific CTL response toward GagYL9 select for HIV escape variants with low fitness that is compensated by intra-codon variation by Honeyborne, I, Leslie, A, Crawford, H, Rousseau, C, Mullins, J, Walker, B, Goulder, P, Prado, J

Cw*0303/0304 HIV specific CTL response toward GagYL9 select for HIV escape variants with low fitness that is compensated by intra-codon variation by Honeyborne, I, Leslie, A, Crawford, H, Rousseau, C, Mullins, J, Walker, B, Goulder, P, Prado, J

HLA-Cw*03-restricted CD8+ T-cell responses targeting the HIV-1 gag major homology region drive virus immune escape and fitness constraints compensated for by intracodon variation. by Honeyborne, I, Codoñer, F, Leslie, A, Tudor-Williams, G, Luzzi, G, Ndung'u, T, Walker, B, Goulder, P, Prado, J

Motif inference reveals optimal CTL epitopes presented by HLA class I alleles highly prevalent in southern Africa. by Honeyborne, I, Rathod, A, Buchli, R, Ramduth, D, Moodley, E, Rathnavalu, P, Chetty, S, Day, C, Brander, C, Hildebrand, W, Walker, B, Kiepiela, P, Goulder, P

Proliferative capacity of epitope-specific CD8 T-cell responses is inversely related to viral load in chronic human immunodeficiency virus type 1 infection. by Day, C, Kiepiela, P, Leslie, A, van der Stok, M, Nair, K, Ismail, N, Honeyborne, I, Crawford, H, Coovadia, H, Goulder, P, Walker, B, Klenerman, P

Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1. by Martinez-Picado, J, Prado, J, Fry, E, Pfafferott, K, Leslie, A, Chetty, S, Thobakgale, C, Honeyborne, I, Crawford, H, Matthews, P, Pillay, T, Rousseau, C, Mullins, J, Brander, C, Walker, B, Stuart, D, Kiepiela, P, Goulder, P

Differential immunogenicity of HIV-1 clade C proteins in eliciting CD8+ and CD4+ cell responses. by Ramduth, D, Chetty, P, Mngquandaniso, N, Nene, N, Harlow, J, Honeyborne, I, Ntumba, N, Gappoo, S, Henry, C, Jeena, P, Addo, M, Altfeld, M, Brander, C, Day, C, Coovadia, H, Kiepiela, P, Goulder, P, Walker, B

Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restrieted gag epitope in chronic human immunodeficien... by Crawford, H, Prado, J, Leslie, A, Hue, S, Honeyborne, I, Reddy, S, van der Stok, M, Mncube, Z, Brander, C, Rousseau, C, Mullins, J, Kaslow, R, Goepfert, P, Allen, S, Hunter, E, Mulenga, J, Kiepiela, P, Walker, B, Goulder, P

Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restricted Gag epitope in chronic human immunodeficien... by Crawford, H, Prado, J, Leslie, A, Hué, S, Honeyborne, I, Reddy, S, van der Stok, M, Mncube, Z, Brander, C, Rousseau, C, Mullins, J, Kaslow, R, Goepfert, P, Allen, S, Hunter, E, Mulenga, J, Kiepiela, P, Walker, B, Goulder, P

Central role of reverting mutations in HLA associations with human immunodeficiency virus set point. by Matthews, P, Prendergast, A, Leslie, A, Crawford, H, Payne, R, Rousseau, C, Rolland, M, Honeyborne, I, Carlson, J, Kadie, C, Brander, C, Bishop, K, Mlotshwa, N, Mullins, J, Coovadia, H, Ndung'u, T, Walker, B, Heckerman, D, Goulder, P

Control of human immunodeficiency virus type 1 is associated with HLA-B*13 and targeting of multiple gag-specific CD8+ T-cell epitopes. by Honeyborne, I, Prendergast, A, Pereyra, F, Leslie, A, Crawford, H, Payne, R, Reddy, S, Bishop, K, Moodley, E, Nair, K, van der Stok, M, McCarthy, N, Rousseau, C, Addo, M, Mullins, J, Brander, C, Kiepiela, P, Walker, B, Goulder, P

Erratum: Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype (Journal of Immunolog... by Leslie, A, Price, D, Mkhize, P, Bishop, K, Rathod, A, Day, C, Crawford, H, Honeyborne, I, Asher, T, Luzzi, G, Edwards, A, Rousseau, C, Mullins, J, Tudor-Williams, G, Novelli, V, Brander, C, Douek, D, Kiepiela, P, Walker, B, Goulder, P

Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype. (vol 177, pg 4699, 2006) by Leslie, A, Price, D, Mkhize, P, Bishop, K, Rathod, A, Day, C, Crawford, H, Honeyborne, I, Asher, T, Luzzi, G, Edwards, A, Rosseau, C, Mullins, J, Tudor-Williams, G, Novelli, V, Brander, C, Douek, D, Kiepiela, P, Walker, B, Goulder, P

Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype. by Leslie, A, Price, D, Mkhize, P, Bishop, K, Rathod, A, Day, C, Crawford, H, Honeyborne, I, Asher, T, Luzzi, G, Edwards, A, Rousseau, C, Rosseau, C, Mullins, J, Tudor-Williams, G, Novelli, V, Brander, C, Douek, D, Kiepiela, P, Walker, B, Goulder, P

Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA. by Leslie, A, Kavanagh, D, Honeyborne, I, Pfafferott, K, Edwards, C, Pillay, T, Hilton, L, Thobakgale, C, Ramduth, D, Draenert, R, Le Gall, S, Luzzi, G, Edwards, A, Brander, C, Sewell, A, Moore, S, Mullins, J, Moore, C, Mallal, S, Bhardwaj, N, Yusim, K, Phillips, R, Klenerman, P, Korber, B, Kiepiela, P

Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA. by Kiepiela, P, Leslie, A, Honeyborne, I, Ramduth, D, Thobakgale, C, Chetty, S, Rathnavalu, P, Moore, C, Pfafferott, K, Hilton, L, Zimbwa, P, Moore, S, Allen, T, Brander, C, Addo, M, Altfeld, M, James, I, Mallal, S, Bunce, M, Barber, L, Szinger, J, Day, C, Klenerman, P, Mullins, J, Korber, B

CD8+ T-cell responses to different HIV proteins have discordant associations with viral load. by Kiepiela, P, Ngumbela, K, Thobakgale, C, Ramduth, D, Honeyborne, I, Moodley, E, Reddy, S, de Pierres, C, Mncube, Z, Mkhwanazi, N, Bishop, K, van der Stok, M, Nair, K, Khan, N, Crawford, H, Payne, R, Leslie, A, Prado, J, Prendergast, A, Frater, J, McCarthy, N, Brander, C, Learn, G, Nickle, D, Rousseau, C

Targeting of a CD8 T cell env epitope presented by HLA-B*5802 is associated with markers of HIV disease progression and lack of selection pressure. by Ngumbela, K, Day, C, Mncube, Z, Nair, K, Ramduth, D, Thobakgale, C, Moodley, E, Reddy, S, de Pierres, C, Mkhwanazi, N, Bishop, K, van der Stok, M, Ismail, N, Honeyborne, I, Crawford, H, Kavanagh, D, Rousseau, C, Nickle, D, Mullins, J, Heckerman, D, Korber, B, Coovadia, H, Kiepiela, P, Goulder, P, Walker, B