Rethinking the Roles of Cancer-Associated Fibroblasts in Pancreatic CancerSummary by Ralph Francescone, Howard C. Crawford, Debora Barbosa Vendramini-Costa

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Myeloid Cell Mediated Immune Suppression in Pancreatic CancerSummary by Samantha B. Kemp, Marina Pasca di Magliano, Howard C. Crawford

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Matrilysin [MMP-7] Expression Selects for Cells with Reduced Sensitivity to Apoptosis by Barbara Fingleton, Tracy Vargo-Gogola, Howard C. Crawford, Lynn M. Matrisian

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Constitutive α- and β-secretase cleavages of the amyloid precursor protein are partially coupled in neurons, but not in frequently used cell lines by Alessio Colombo, Huanhuan Wang, Peer-Hendrik Kuhn, Richard Page, Elisabeth Kremmer, Peter J. Dempsey, Howard C. Crawford, Stefan F. Lichtenthaler

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Mutant KRas-Induced Mitochondrial Oxidative Stress in Acinar Cells Upregulates EGFR Signaling to Drive Formation of Pancreatic Precancerous Lesions by Geou-Yarh Liou, Heike Döppler, Kathleen E. DelGiorno, Lizhi Zhang, Michael Leitges, Howard C. Crawford, Michael P. Murphy, Peter Storz

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<em>Prkci</em> Regulates Autophagy and Pancreatic Tumorigenesis in Mice by Kristin S. Inman, Yi Liu, Michele L. Scotti Buzhardt, Michael Leitges, Murli Krishna, Howard C. Crawford, Alan P. Fields, Nicole R. Murray

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Persistent salmonellosis causes pancreatitis in a murine model of infection. by Kathleen E DelGiorno, Jason W Tam, Jason C Hall, Gangadaar Thotakura, Howard C Crawford, Adrianus W M van der Velden

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Activation of the intrinsic fibroinflammatory program in adult pancreatic acinar cells triggered by Hippo signaling disruption. by Jun Liu, Ming Gao, Michael Nipper, Janice Deng, Francis E Sharkey, Randy L Johnson, Howard C Crawford, Yidong Chen, Pei Wang

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Inhibition of Tumor Microenvironment Cytokine Signaling Sensitizes Ovarian Cancer Cells to Antiestrogen Therapy by Lijun Tan, Katelyn Tondo-Steele, Caroline Foster, Carrie McIlwain, Danielle E. Bolland, Howard C. Crawford, Andrew Sciallis, Karen McLean

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Epithelial-Myeloid cell crosstalk regulates acinar cell plasticity and pancreatic remodeling in mice by Yaqing Zhang, Wei Yan, Esha Mathew, Kevin T Kane, Arthur Brannon III, Maeva Adoumie, Alekya Vinta, Howard C Crawford, Marina Pasca di Magliano

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Protein kinase C iota regulates pancreatic acinar-to-ductal metaplasia. by Michele L Scotti, Kristin E Smith, Amanda M Butler, Shelly R Calcagno, Howard C Crawford, Michael Leitges, Alan P Fields, Nicole R Murray

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Myeloid Cell-Derived HB-EGF Drives Tissue Recovery After PancreatitisSummary by Hui-Ju Wen, Shan Gao, Yin Wang, Michael Ray, Mark A. Magnuson, Christopher V.E. Wright, Marina Pasca Di Magliano, Timothy L. Frankel, Howard C. Crawford

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Hypoxia promotes an inflammatory phenotype of fibroblasts in pancreatic cancer by Ashley M. Mello, Tenzin Ngodup, Yusoo Lee, Katelyn L. Donahue, Jinju Li, Arvind Rao, Eileen S. Carpenter, Howard C. Crawford, Marina Pasca di Magliano, Kyoung Eun Lee

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A Bitter Taste Receptor as a Novel Molecular Target on Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma by Jessica Hung, Samantha M. Perez, Siva Sai Krishna Dasa, Sarah P. Hall, Danielle B. Heckert, Brian P. Murphy, Howard C. Crawford, Kimberly A. Kelly, Lindsey T. Brinton

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Deficiencies of the lipid-signaling enzymes phospholipase D1 and D2 alter cytoskeletal organization, macrophage phagocytosis, and cytokine-stimulated neutrophil recruitment. by Wahida H Ali, Qin Chen, Kathleen E Delgiorno, Wenjuan Su, Jason C Hall, Tsunaki Hongu, Huasong Tian, Yasunori Kanaho, Gilbert Di Paolo, Howard C Crawford, Michael A Frohman

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Loss of the ciliary protein Chibby1 in mice leads to exocrine pancreatic degeneration and pancreatitis by Benjamin Cyge, Vera Voronina, Mohammed Hoque, Eunice N. Kim, Jason Hall, Jennifer M. Bailey-Lundberg, Gregory J. Pazour, Howard C. Crawford, Randall T. Moon, Feng-Qian Li, Ken-Ichi Takemaru

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Differential Contribution of Pancreatic Fibroblast Subsets to the Pancreatic Cancer StromaSummary by Paloma E. Garcia, Maeva Adoumie, Esther C. Kim, Yaqing Zhang, Michael K. Scales, Yara S. El-Tawil, Amara Z. Shaikh, Hui-Ju Wen, Filip Bednar, Ben L. Allen, Deneen M. Wellik, Howard C. Crawford, Marina Pasca di Magliano

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HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties by Ethan V Abel, Masashi Goto, Brian Magnuson, Saji Abraham, Nikita Ramanathan, Emily Hotaling, Anthony A Alaniz, Chandan Kumar-Sinha, Michele L Dziubinski, Sumithra Urs, Lidong Wang, Jiaqi Shi, Meghna Waghray, Mats Ljungman, Howard C Crawford, Diane M Simeone

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Arginase 1 is a key driver of immune suppression in pancreatic cancer by Rosa E Menjivar, Zeribe C Nwosu, Wenting Du, Katelyn L Donahue, Hanna S Hong, Carlos Espinoza, Kristee Brown, Ashley Velez-Delgado, Wei Yan, Fatima Lima, Allison Bischoff, Padma Kadiyala, Daniel Salas-Escabillas, Howard C Crawford, Filip Bednar, Eileen Carpenter, Yaqing Zhang, Christopher J Halbrook, Costas A Lyssiotis, Marina Pasca di Magliano

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Combinatorial Gli activity directs immune infiltration and tumor growth in pancreatic cancer. by Michael K Scales, Ashley Velez-Delgado, Nina G Steele, Hannah E Schrader, Anna M Stabnick, Wei Yan, Nayanna M Mercado Soto, Zeribe C Nwosu, Craig Johnson, Yaqing Zhang, Daniel J Salas-Escabillas, Rosa E Menjivar, H Carlo Maurer, Howard C Crawford, Filip Bednar, Kenneth P Olive, Marina Pasca di Magliano, Benjamin L Allen

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