Howard Hughes Medical Institute

HHMI founder [[Howard Hughes The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization headquartered in Chevy Chase, Maryland with additional facilities in Ashburn, Virginia. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, film director, and philanthropist, known during his lifetime as one of the most financially successful individuals in the world. It is one of the largest private funding organizations for biological and medical research in the United States. HHMI spends about $1 million per HHMI Investigator per year, which amounts to annual investment in biomedical research of about $825 million.

The institute has an endowment of $22.6 billion, making it the second-wealthiest philanthropic organization in the United States and the second-best-endowed medical research foundation in the world. HHMI is the former owner of the Hughes Aircraft Company, an American aerospace firm that was divested to various firms over time. Provided by Wikipedia
Showing 1 - 20 results of 29 for search 'Howard Hughes Medical Institute', query time: 0.06s Refine Results
  1. 1
    A Chromatin-Dependent Role of the Fragile X Mental Retardation Protein FMRP in the DNA Damage Response

    A Chromatin-Dependent Role of the Fragile X Mental Retardation Protein FMRP in the DNA Damage Response by Alpatov, Roman, Nakamoto-Kinoshita, Mika, Blanco, Andres, Chen, Shuzhen, Stützer, Alexandra, Armache, Karim J., Simon, Matthew D., Xu, Chao, Ali, Muzaffar, Murn, Jernej, Prisic, Sladjana, Kutateladze, Tatiana G., Vakoc, Christopher R., Min, Jinrong, Kingston, Robert E., Fischle, Wolfgang, Warren, Stephen T., Shi, Yang, Lesch, Bluma, Page, David C

    Published 2017
    Other Authors: “…Howard Hughes Medical Institute…”
    Get full text
    Get full text
    Article
  2. 2
    Proteotoxic Stress Induces a Cell-Cycle Arrest by Stimulating Lon to Degrade the Replication Initiator DnaA

    Proteotoxic Stress Induces a Cell-Cycle Arrest by Stimulating Lon to Degrade the Replication Initiator DnaA by Liu, Jing, Jonas, Kristina, Laub, Michael T, Chien, Peter, 1976-

    Published 2017
    Other Authors: “…Howard Hughes Medical Institute…”
    Get full text
    Get full text
    Article
  3. 3
    Conformational Motions and Water Networks at the α/β Interface in E. coli Ribonucleotide Reductase

    Conformational Motions and Water Networks at the α/β Interface in E. coli Ribonucleotide Reductase by Reinhardt, Clorice R, Li, Pengfei, Kang, Gyunghoon, Stubbe, JoAnne, Drennan, Catherine L, Hammes-Schiffer, Sharon

    Published 2021
    Other Authors: “…Howard Hughes Medical Institute…”
    Get full text
    Article
  4. 4
    The Organoid Cell Atlas

    The Organoid Cell Atlas by Bock, Christoph, Boutros, Michael, Camp, J Gray, Clarke, Laura, Clevers, Hans, Knoblich, Juergen A, Liberali, Prisca, Regev, Aviv, Rios, Anne C, Stegle, Oliver, Stunnenberg, Hendrik G, Teichmann, Sarah A, Treutlein, Barbara, Vries, Robert GJ

    Published 2021
    Other Authors: “…Howard Hughes Medical Institute…”
    Get full text
    Article
  5. 5
    Comparative tRNA sequencing and RNA mass spectrometry for surveying tRNA modifications

    Comparative tRNA sequencing and RNA mass spectrometry for surveying tRNA modifications by Kimura, Satoshi, Dedon, Peter C, Waldor, Matthew K

    Published 2022
    Other Authors: “…Howard Hughes Medical Institute…”
    Get full text
    Article
  6. 6
    Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma

    Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma by Regev, Aviv

    Published 2022
    Other Authors: “…Howard Hughes Medical Institute…”
    Get full text
    Article
  7. 7
    Muscle and neuronal guidepost-like cells facilitate planarian visual system regeneration

    Muscle and neuronal guidepost-like cells facilitate planarian visual system regeneration by Scimone, M. Lucila, Atabay, Kutay D, Fincher, Christopher T., Bonneau, Ashley R, Li, Dayan, Reddien, Peter

    Published 2022
    Other Authors: “…Howard Hughes Medical Institute…”
    Get full text
    Article
  8. 8
    An hourglass circuit motif transforms a motor program via subcellularly localized muscle calcium signaling and contraction

    An hourglass circuit motif transforms a motor program via subcellularly localized muscle calcium signaling and contraction by Sando, Steven R, Bhatla, Nikhil, Lee, Eugene LQ, Horvitz, H Robert

    Published 2022
    Other Authors: “…Howard Hughes Medical Institute…”
    Get full text
    Article
  9. 9
    Cell Atlas of The Human Fovea and Peripheral Retina

    Cell Atlas of The Human Fovea and Peripheral Retina by Yan, Wenjun, Peng, Yi-Rong, van Zyl, Tavé, Regev, Aviv, Shekhar, Karthik, Juric, Dejan, Sanes, Joshua R

    Published 2021
    Other Authors: “…Howard Hughes Medical Institute…”
    Get full text
    Article
  10. 10
    Radiation-induced neoantigens broaden the immunotherapeutic window of cancers with low mutational loads

    Radiation-induced neoantigens broaden the immunotherapeutic window of cancers with low mutational loads by Lussier, Danielle M., Alspach, Elise, Ward, Jeffrey P., Miceli, Alexander P., Runci, Daniele, White, J. Michael, Mpoy, Cedric, Arthur, Cora D., Kohlmiller, Heather N., Jacks, Tyler, Artyomov, Maxim N., Rogers, Buck E., Schreiber, Robert D.

    Published 2022
    Other Authors: “…Howard Hughes Medical Institute…”
    Get full text
    Article
  11. 11
    MicroRNA Clustering Assists Processing of Suboptimal MicroRNA Hairpins through the Action of the ERH Protein

    MicroRNA Clustering Assists Processing of Suboptimal MicroRNA Hairpins through the Action of the ERH Protein by Fang, Wenwen, Bartel, David P

    Published 2021
    Other Authors: “…Howard Hughes Medical Institute…”
    Get full text
    Article
  12. 12
    Cell atlas of aqueous humor outflow pathways in eyes of humans and four model species provides insight into glaucoma pathogenesis

    Cell atlas of aqueous humor outflow pathways in eyes of humans and four model species provides insight into glaucoma pathogenesis by van Zyl, Tavé, Yan, Wenjun, McAdams, Alexi, Peng, Yi-Rong, Shekhar, Karthik, Regev, Aviv, Juric, Dejan, Sanes, Joshua R

    Published 2022
    Other Authors: “…Howard Hughes Medical Institute…”
    Get full text
    Article
  13. 13
    H3.3 Nucleosome Assembly Mutants Display a Late-Onset Maternal Effect

    H3.3 Nucleosome Assembly Mutants Display a Late-Onset Maternal Effect by Burkhart, Kirk B, Sando, Steven R, Corrionero, Anna, Horvitz, H Robert

    Published 2021
    Other Authors: “…Howard Hughes Medical Institute…”
    Get full text
    Article
  14. 14
    Structure of a trapped radical transfer pathway within a ribonucleotide reductase holocomplex

    Structure of a trapped radical transfer pathway within a ribonucleotide reductase holocomplex by Kang, Gyunghoon, Taguchi, Alexander T., Stubbe, JoAnne, Drennan, Catherine L.

    Published 2022
    Other Authors: “…Howard Hughes Medical Institute…”
    Get full text
    Article
  15. 15
    Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma

    Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma by Regev, Aviv

    Published 2022
    Other Authors: “…Howard Hughes Medical Institute…”
    Get full text
    Article
  16. 16
    The Taste Receptor TAS1R3 Regulates Small Intestinal Tuft Cell Homeostasis

    The Taste Receptor TAS1R3 Regulates Small Intestinal Tuft Cell Homeostasis by Howitt, Michael R, Cao, Y Grace, Gologorsky, Matthew B, Li, Jessica A, Haber, Adam L, Biton, Moshe, Lang, Jessica, Michaud, Monia, Regev, Aviv, Garrett, Wendy S

    Published 2021
    Other Authors: “…Howard Hughes Medical Institute…”
    Get full text
    Article
  17. 17
    MicroRNAs Cause Accelerated Decay of Short-Tailed Target mRNAs

    MicroRNAs Cause Accelerated Decay of Short-Tailed Target mRNAs by Eisen, Timothy Jonas, Eichhorn, Stephen William, Subtelny, Alexander Orest, Bartel, David

    Published 2022
    Other Authors: “…Howard Hughes Medical Institute…”
    Get full text
    Article
  18. 18
    Decoding human fetal liver haematopoiesis

    Decoding human fetal liver haematopoiesis by Regev, Aviv

    Published 2022
    Other Authors: “…Howard Hughes Medical Institute…”
    Get full text
    Article
  19. 19
    The biochemical basis of microRNA targeting efficacy

    The biochemical basis of microRNA targeting efficacy by McGeary, Sean E, Lin, Kathy S, Shi, Charlie Y, Pham, Thy M, Bisaria, Namita, Kelley, Gina M, Bartel, David P

    Published 2021
    Other Authors: “…Howard Hughes Medical Institute…”
    Get full text
    Article
  20. 20
    Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase from Leishmania major

    Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase from Leishmania major by Feliciano, Patricia R, Drennan, Catherine L

    Published 2021
    Other Authors: “…Howard Hughes Medical Institute…”
    Get full text
    Article

Search Tools: