Tracing traditions: patterns of technological innovation and the circulation of copper in Southwest Asia from the 8th to 1st millennia BCE by Howarth, P

Development of an epithelial-derived airflow obstruction gene expression signature using systems approaches by Roberts, S, Richardson, M, Hinks, TSC, Howarth, P, Bradding, P, Wenzel, SE, Siddiqui, S

Human responses to climate change in the late prehistoric Western Loess Plateau, northwest China by Chen, T, Qiu, M, Liu, R, Li, H, Hou, H, Howarth, P, Bowring, S, Zhou, A

Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial. by Pavord, I, Korn, S, Howarth, P, Bleecker, E, Buhl, R, Keene, O, Ortega, H, Chanez, P

Multi-tissue transcriptomics delineates the diversity of airway T cell functions in asthma by Singhania, A, Wallington, J, Smith, C, Horowitz, D, Staples, K, Howarth, P, Gadola, S, Djukanovic, R, Woelk, C, Hinks, T

The upper and lower airway microbiome in severe asthma by Jabeen, M, Sanderson, N, Barber, C, Lau, LCK, Pavord, ID, Chauhan, A, Klenerman, P, Street, T, Howarth, P, Hinks, TSC

Structure–mechanics relationships of collagen fibrils in the osteogenesis imperfecta mouse model by Andriotis, O. G., Chang, S. W., Vanleene, M., Howarth, P. H., Davies, D. E., Shefelbine, S. J., Thurner, P. J., Buehler, Markus J

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Social hierarchy and the choice of metal recycling at Anyang, the last capital of Bronze Age Shang China by Liu, R, Pollard, AM, Cao, Q, Liu, C, Sainsbury, V, Howarth, P, Bray, P, Huan, L, Yao, B, Fu, Y, Tang, J

Multidimensional endotyping in patients with severe asthma reveals inflammatory heterogeneity in matrix metalloproteinases and chitinase 3–like protein 1 by Hinks, T, Brown, T, Lau, L, Rupani, H, Barber, C, Elliott, S, Ward, J, Ono, J, Ohta, S, Izuhara, K, Djukanović, R, Kurukulaaratchy, R, Chauhan, A, Howarth, P

Species-level, metagenomic and proteomic analysis of microbe-immune interactions in severe asthma by Jabeen, M, Sanderson, N, Tine, M, Donachie, G, Barber, C, Azim, A, Lau, L, Brown, T, Pavord, I, Chauhan, A, Klenerman, P, Street, T, Marchi, E, Howarth, P, Hinks, TC

IL-6 trans-signaling definesa new asthma phenotype associated with frequent exacerbations, increased airway inflammation and impaired epithelial integrity by Olsson, H, Jevnikar, Z, Ostling, J, Ax, E, Thorn, K, Oberg, L, Van Geest, M, Vaarala, O, Singhania, A, James, A, Wilson, S, Hinks, T, Howarth, P, U-BIOPRED Study Group

Airway remodelling rather than cellular infiltration characterises both type2 cytokine biomarker-high and -low severe asthma by Khalfaoui, L, Symon, F, Couillard, S, Hargadon, B, Chaudhuri, R, Bicknell, S, Mansur, A, Shrimanker, R, Hinks, T, Pavord, I, Fowler, S, Brown, V, McGarvey, L, Heaney, L, Austin, C, Howarth, P, Arron, J, Choy, D, Bradding, P

Nocturnal temperature-controlled laminar airflow device for adults with severe allergic asthma: the LASER RCT by Kapoor, M, Storrar, W, Balls, L, Brown, T, Mansur, A, Hedley, E, Jones, T, Roberts, C, Shirkey, B, Dutton, S, Luengo-Fernandez, R, Little, M, Dewey, A, Marshall, S, Fogg, C, Boughton, K, Rahman, N, Yu, L, Bradding, P, Howarth, P, Chauhan, A

Genome-wide association study to identify genetic determinants of severe asthma. by Wan, Y, Shrine, N, Soler Artigas, M, Wain, L, Blakey, J, Moffatt, M, Bush, A, Chung, K, Cookson, W, Strachan, D, Heaney, L, Al-Momani, B, Mansur, A, Manney, S, Thomson, N, Chaudhuri, R, Brightling, C, Bafadhel, M, Singapuri, A, Niven, R, Simpson, A, Holloway, J, Howarth, P, Hui, J, Musk, A

Genome-wide association study to identify genetic determinants of severe asthma by Wan, Y, Shrine, N, Artigas, MS, Wain, L, Blakey, J, Moffatt, M, Bush, A, Chung, K, Cookson, W, Strachan, D, Heaney, L, Al-Momani, B, Mansur, A, Manney, S, Thomson, N, Chaudhuri, R, Brightling, C, Bafadhel, M, Singapuri, A, Niven, R, Simpson, A, Holloway, J, Howarth, P, Hui, J, Musk, A, James, A, Brown, M, Baltic, S, Ferreira, M, Thompson, P, Tobin, MD, Sayers, I, Hall, I

Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation by Jevnikar, Z, Östling, J, Ax, E, Calvén, J, Thörn, K, Israelsson, E, Öberg, L, Singhania, A, Lau, L, Wilson, S, Ward, J, Chauhan, A, Sousa, A, De Meulder, B, Loza, M, Baribaud, F, Sterk, P, Chung, K, Sun, K, Guo, Y, Adcock, I, Payne, D, Dahlen, B, Chanez, P, Shaw, D, Krug, N, Hohlfeld, J, Sandström, T, Djukanovic, R, James, A, Hinks, T, Howarth, P, Vaarala, O, van Geest, M, Olsson, H

Erratum to: Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5) by Bousquet, J, Farrell, J, Crooks, G, Hellings, P, Bel, E, Bewick, M, Chavannes, N, de Sousa, J, Cruz, A, Haahtela, T, Joos, G, Khaltaev, N, Malva, J, Muraro, A, Nogues, M, Palkonen, S, Pedersen, S, Robalo-Cordeiro, C, Samolinski, B, Strandberg, T, Valiulis, A, Yorgancioglu, A, Zuberbier, T, Bedbrook, A, Aberer, W, Adachi, M, Agusti, A, Akdis, C, Akdis, M, Ankri, J, Alonso, A, Annesi-Maesano, I, Ansotegui, I, Anto, J, Arnavielhe, S, Arshad, H, Bai, C, Baiardini, I, Bachert, C, Baigenzhin, A, Barbara, C, Bateman, E, Beghé, B, Kheder, A, Bennoor, K, Benson, M, Bergmann, K, Bieber, T, Bindslev-Jensen, C, Bjermer, L, Blain, H, Blasi, F, Boner, A, Bonini, M, Bonini, S, Bosnic-Anticevitch, S, Boulet, L, Bourret, R, Bousquet, P, Braido, F, Briggs, A, Brightling, C, Brozek, J, Buhl, R, Burney, P, Bush, A, Caballero-Fonseca, F, Caimmi, D, Calderon, M, Calverley, P, Camargos, P, Canonica, G, Camuzat, T, Carlsen, K, Carr, W, Carriazo, A, Casale, T, Cepeda Sarabia, A, Chatzi, L, Chen, Y, Chiron, R, Chkhartishvili, E, Chuchalin, A, Chung, K, Ciprandi, G, Cirule, I, Cox, L, Costa, D, Custovic, A, Dahl, R, Dahlen, S, Darsow, U, De Carlo, G, De Blay, F, Dedeu, T, Deleanu, D, De Manuel Keenoy, E, Demoly, P, Denburg, J, Devillier, P, Didier, A, Dinh-Xuan, A, Djukanovic, R, Dokic, D, Douagui, H, Dray, G, Dubakiene, R, Durham, S, Dykewicz, M, El-Gamal, Y, Emuzyte, R, Fabbri, L, Fletcher, M, Fiocchi, A, Fink Wagner, A, Fonseca, J, Fokkens, W, Forastiere, F, Frith, P, Gaga, M, Gamkrelidze, A, Garces, J, Garcia-Aymerich, J, Gemicioğlu, B, Gereda, J, González Diaz, S, Gotua, M, Grisle, I, Grouse, L, Gutter, Z, Guzmán, M, Heaney, L, Hellquist-Dahl, B, Henderson, D, Hendry, A, Heinrich, J, Heve, D, Horak, F, Hourihane, J, Howarth, P, Humbert, M, Hyland, M, Illario, M, Ivancevich, J, Jardim, J, Jares, E, Jeandel, C, Jenkins, C, Johnston, S, Jonquet, O, Julge, K, Jung, K, Just, J, Kaidashev, I, Khaitov, M, Kalayci, O, Kalyoncu, A, Keil, T, Keith, P, Klimek, L, Koffi N'Goran, B, Kolek, V, Koppelman, G, Kowalski, M, Kull, I, Kuna, P, Kvedariene, V, Lambrecht, B, Lau, S, Larenas-Linnemann, D, Laune, D, Le, L, Lieberman, P, Lipworth, B, Li, J, Lodrup Carlsen, K, Louis, R, MacNee, W, Magard, Y, Magnan, A, Mahboub, B, Mair, A, Majer, I, Makela, M, Manning, P, Mara, S, Marshall, G, Masjedi, M, Matignon, P, Maurer, M, Mavale-Manuel, S, Melén, E, Melo-Gomes, E, Meltzer, E, Menzies-Gow, A, Merk, H, Michel, J, Miculinic, N, Mihaltan, F, Milenkovic, B, Mohammad, G, Molimard, M, Momas, I, Montilla-Santana, A, Morais-Almeida, M, Morgan, M, Mösges, R, Mullol, J, Nafti, S, Namazova-Baranova, L, Naclerio, R, Neou, A, Neffen, H, Nekam, K, Niggemann, B, Ninot, G, Nyembue, T, O'Hehir, R, Ohta, K, Okamoto, Y, Okubo, K, Ouedraogo, S, Paggiaro, P, Pali-Schöll, I, Panzner, P, Papadopoulos, N, Papi, A, Park, H, Passalacqua, G, Pavord, I, Pawankar, R, Pengelly, R, Pfaar, O, Picard, R, Pigearias, B, Pin, I, Plavec, D, Poethig, D, Pohl, W, Popov, T, Portejoie, F, Potter, P, Postma, D, Price, D, Rabe, K, Raciborski, F, Radier Pontal, F, Repka-Ramirez, S, Reitamo, S, Rennard, S, Rodenas, F, Roberts, J, Roca, J, Rodriguez Mañas, L, Rolland, C, Roman Rodriguez, M, Romano, A, Rosado-Pinto, J, Rosario, N, Rosenwasser, L, Rottem, M, Ryan, D, Sanchez-Borges, M, Scadding, G, Schunemann, H, Serrano, E, Schmid-Grendelmeier, P, Schulz, H, Sheikh, A, Shields, M, Siafakas, N, Sibille, Y, Similowski, T, Simons, F, Sisul, J, Skrindo, I, Smit, H, Solé, D, Sooronbaev, T, Spranger, O, Stelmach, R, Sterk, P, Sunyer, J, Thijs, C, To, T, Todo-Bom, A, Triggiani, M, Valenta, R, Valero, A, Valia, E, Valovirta, E, Van Ganse, E, van Hage, M, Vandenplas, O, Vasankari, T, Vellas, B, Vestbo, J, Vezzani, G, Vichyanond, P, Viegi, G, Vogelmeier, C, Vontetsianos, T, Wagenmann, M, Wallaert, B, Walker, S, Wang, D, Wahn, U, Wickman, M, Williams, D, Williams, S, Wright, J, Yawn, B, Yiallouros, P, Yusuf, O, Zaidi, A, Zar, H, Zernotti, M, Zhang, L, Zhong, N, Zidarn, M, Mercier, J