Discovery of novel and potent P2Y14R antagonists via structure-based virtual screening for the treatment of acute gouty arthritis by Weiwei Wang, Chunxiao Liu, Hanwen Li, Sheng Tian, Yingxian Liu, Nanxi Wang, Duanyang Yan, Huanqiu Li, Qinghua Hu

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GPR105-Targeted Therapy Promotes Gout Resolution as a Switch Between NETosis and Apoptosis of Neutrophils by Chunxiao Liu, Chunxiao Liu, Mengze Zhou, Wenjiao Jiang, Shumin Ye, Sheng Tian, Cheng Jiang, Kun Hao, Huanqiu Li, Qinghua Hu, Qinghua Hu

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Targeting P2Y14R protects against necroptosis of intestinal epithelial cells through PKA/CREB/RIPK1 axis in ulcerative colitis by Chunxiao Liu, Hui Wang, Lu Han, Yifan Zhu, Shurui Ni, Jingke Zhi, Xiping Yang, Jiayi Zhi, Tian Sheng, Huanqiu Li, Qinghua Hu

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A novel SRSF3 inhibitor, SFI003, exerts anticancer activity against colorectal cancer by modulating the SRSF3/DHCR24/ROS axis by Yawen Zhang, Mengmeng Wang, Fanyi Meng, Man Yang, Yinshuang Chen, Xuqin Guo, Weiwei Wang, Yifan Zhu, Yundi Guo, Chunlai Feng, Shen Tian, Hongjian Zhang, Huanqiu Li, Jing Sun, Weipeng Wang

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FDW028, a novel FUT8 inhibitor, impels lysosomal proteolysis of B7-H3 via chaperone-mediated autophagy pathway and exhibits potent efficacy against metastatic colorectal cancer by Mengmeng Wang, Zhoudong Zhang, Mengxi Chen, Yixin Lv, Sheng Tian, Fanyi Meng, Yawen Zhang, Xuqin Guo, Yinshuang Chen, Man Yang, Jiawei Li, Tian Qiu, Fang Xu, Zhi Li, Qi Zhang, Jie Yang, Jing Sun, Hongjian Zhang, Haiyang Zhang, Huanqiu Li, Weipeng Wang

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