Target engagement: shining a light by Huber, K

Mapping the chemical chromatin reactivation landscape identifies BRD4-TAF1 cross-talk by Huber, K, Knapp, S, Fedorov, O

PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers. by Brault, L, Gasser, C, Bracher, F, Huber, K, Knapp, S, Schwaller, J

KH-TFMDI, a novel sirtuin inhibitor, alters the cytoskeleton and mitochondrial metabolism promoting cell death in Leishmania amazonensis by Verçoza, B, Godinho, J, de Macedo-Silva, S, Huber, K, Bracher, F, de Souza, W, Rodrigues, J

Alterations on growth and cell organization of Giardia intestinalis trophozoites after treatment with KH-TFMDI, a novel class III histone deacetylase inhibitor by Gadelha, A, Bravim, B, Vidal, J, Reignault, L, Cosme, B, Huber, K, Bracher, F, De Souza, W

Chemical instability and promiscuity of arylmethylidenepyrazolinone-based MDMX inhibitors by Stefaniak, J, Lewis, A, Conole, D, Galan, S, Bataille, C, Wynne, G, Castaldi, M, Lundbäck, T, Russell, A, Huber, K

Lapatinib potentiates cytotoxicity of YM155 in neuroblastoma via inhibition of the ABCB1 efflux transporter by Radic-Sarikas, B, Halasz, M, Huber, K, Winter, G, Tsafou, K, Papamarkou, T, Brunak, S, Kolch, W, Superti-Furga, G

Adhesion molecule expression and cell cycle control in cells of the immune system are sensitive to altered gravity by Kroll H, Zipp F, von der Wiesche M, Hemmersbach R, Huber K, Paulsen K, Thiel C, Ullrich O, Engelmann F

Quantifying target occupancy of small molecules within living cells by Robers, MB, Friedman-Ohana, R, Huber, K, Kilpatrick, L, Vasta, JD, Berger, B-T, Chaudhry, C, Hill, S, Müller, S, Knapp, S, Wood, KV

Composition and seasonality of Culicoides in three host environments in Rabat region (Morocco) by Bourquia, M, Garros, C, Rakotoarivony, I, Boukhari, I, Chakrani, M, Huber, K, Gardès, L, Wint, W, Baldet, T, Khallaayoune, K, Balenghien, T

Re-evaluating the mechanism of action of α,β-unsaturated carbonyl DUB inhibitors B-AP15 and VLX1570: a paradigmatic example of unspecific protein crosslinking with Michael acceptor... by Ward, J, Pinto-Fernandez, A, Cornelissen, L, Bonham, S, Diaz Saez, L, Riant, O, Huber, K, Kessler, B, Feron, O, Tate, E

7,8-dichloro-1-oxo-β-carbolines as a versatile scaffold for the development of potent and selective kinase inhibitors with unusual binding modes. by Huber, K, Brault, L, Fedorov, O, Gasser, C, Filippakopoulos, P, Bullock, A, Fabbro, D, Trappe, J, Schwaller, J, Knapp, S, Bracher, F

Combinatorial drug screening identifies Ewing sarcoma-specific sensitivities by Radic-Sarikas, B, Tsafou, K, Emdal, K, Papamarkou, T, Huber, K, Mutz, C, Toretsky, J, Bennett, K, Olsen, J, Brunak, S, Kovar, H, Superti-Furga, G

Specific CLK inhibitors from a novel chemotype for regulation of alternative splicing. by Fedorov, O, Huber, K, Eisenreich, A, Filippakopoulos, P, King, O, Bullock, A, Szklarczyk, D, Jensen, L, Fabbro, D, Trappe, J, Rauch, U, Bracher, F, Knapp, S

Specific CLK inhibitors from a novel chemotype for regulation of alternative splicing. by Fedorov, O, Huber, K, Eisenreich, A, Filippakopoulos, P, King, O, Bullock, A, Szklarczyk, D, Jensen, L, Fabbro, D, Trappe, J, Rauch, U, Bracher, F, Knapp, S

Thiazolidine derivatives as potent and selective inhibitors of the PIM kinase family. by Bataille, C, Brennan, M, Byrne, S, Davies, S, Durbin, M, Fedorov, O, Huber, K, Jones, A, Knapp, S, Liu, G, Nadali, A, Quevedo, C, Russell, A, Walker, R, Westwood, R, Wynne, G

General mechanisms of coagulation and targets of anticoagulants (Section I). Position Paper of the ESC Working Group on Thrombosis--Task Force on Anticoagulants in Heart Disease. by De Caterina, R, Husted, S, Wallentin, L, Andreotti, F, Arnesen, H, Bachmann, F, Baigent, C, Huber, K, Jespersen, J, Kristensen, S, Lip, G, Morais, J, Rasmussen, L, Siegbahn, A, Verheugt, F, Weitz, J

Parenteral anticoagulants in heart disease: current status and perspectives (Section II). Position paper of the ESC Working Group on Thrombosis-Task Force on Anticoagulants in Hear... by De Caterina, R, Husted, S, Wallentin, L, Andreotti, F, Arnesen, H, Bachmann, F, Baigent, C, Huber, K, Jespersen, J, Kristensen, S, Lip, G, Morais, J, Rasmussen, L, Siegbahn, A, Verheugt, F, Weitz, J

New oral anticoagulants in atrial fibrillation and acute coronary syndromes: ESC Working Group on Thrombosis-Task Force on Anticoagulants in Heart Disease position paper. by De Caterina, R, Husted, S, Wallentin, L, Andreotti, F, Arnesen, H, Bachmann, F, Baigent, C, Huber, K, Jespersen, J, Kristensen, S, Lip, G, Morais, J, Rasmussen, L, Siegbahn, A, Verheugt, F, Weitz, J

Vitamin K antagonists in heart disease: current status and perspectives (Section III). Position paper of the ESC Working Group on Thrombosis--Task Force on Anticoagulants in Heart... by De Caterina, R, Husted, S, Wallentin, L, Andreotti, F, Arnesen, H, Bachmann, F, Baigent, C, Huber, K, Jespersen, J, Kristensen, S, Lip, G, Morais, J, Rasmussen, L, Siegbahn, A, Verheugt, F, Weitz, J