Genetic abrogation of immune checkpoints in antigen-specific cytotoxic T-lymphocyte as a potential alternative to blockade immunotherapy অনুযায়ী Zhang, C, Peng, Y, Hublitz, P, Zhang, H, Dong, T

Rapid emergence of chronic lymphocytic leukemia during JAK2 inhibitor therapy in a patient with myelofibrosis অনুযায়ী Sousos, N, Buck, G, Rodriguez-Meira, A, Norfo, R, Hamblin, A, Pezzella, F, Davies, J, Hublitz, P, Psaila, B, Mead, AJ

Infection with a Brazilian isolate of Zika virus generates RIG‐I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signalling অনুযায়ী Hertzog, J, Dias, A, Rigby, R, Donald, C, Mayer, A, Sezgin, E, Song, C, Jin, B, Hublitz, P, Eggeling, C, Kohl, A, Rehwinkel, J

Autophagy-dependent generation of free fatty acids is critical for normal neutrophil differentiation অনুযায়ী Riffelmacher, T, Clarke, A, Richter, F, Stranks, A, Pandey, S, Danielli, S, Hublitz, P, Yu, Z, Johnson, E, Schwerd, T, McCullagh, J, Uhlig, H, Jacobsen, S, Simon, A

Microhomologies are prevalent at Cas9-induced larger deletions অনুযায়ী Owens, D, Caulder, A, Frontera, V, Harman, J, Allan, A, Bucakci, A, Greder, L, Codner, G, Hublitz, P, McHugh, P, Teboul, L, De Bruijn, M

Polyamines control eIF5A hypusination, TFEB translation, and autophagy to reverse B cell senescence অনুযায়ী Zhang, H, Alsaleh, G, Feltham, J, Sun, Y, Napolitano, G, Riffelmacher, T, Charles, P, Frau, L, Hublitz, P, Yu, Z, Mohammed, S, Ballabio, A, Balabanov, S, Mellor, J, Simon, A

SARS-CoV-2 mutations affect antigen processing by the proteasome to alter CD8+ T cell responses অনুযায়ী Wellington, D, Yin, Z, Yu, Z, Heilig, R, Davis, S, Fischer, R, Felce, SL, Antoun, E, Hublitz, P, Beveridge, R, Dong, D, Liu, G, Yao, X, Peng, Y, Kessler, B, Dong, T

Dual RNA sequencing reveals dendritic cell reprogramming in response to typhoidal Salmonella invasion অনুযায়ী Aulicino, A, Antanaviciute, A, Frost, J, Sousa Geros, A, Mellado, E, Attar, M, Jagielowicz, M, Hublitz, P, Sinz, J, Preciado-Llanes, L, Napolitani, G, Bowden, R, Koohy, H, Drakesmith, AH, Simmons, A

GTP cyclohydrolase drives breast cancer development and promotes EMT in an enzyme-independent manner অনুযায়ী Wang, Z, Zhang, N, Zhang, M, Jiang, Y, Fischer, R, Ng, AS, Bridges, E, Zhang, W, Zeng, X, Luo, Q, Liang, J, Győrffy, B, Hublitz, P, Liang, Z, Kerr, D, Harris, AL, Cai, S

SCL/TAL1 cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells অনুযায়ী Chagraoui, H, Kristiansen, MS, Ruiz, JP, Serra-Barros, A, Richter, J, Hall-Ponselé, E, Gray, N, Waithe, D, Clark, K, Hublitz, P, Repapi, E, Otto, G, Sopp, P, Taylor, S, Thongjuea, S, Vyas, P, Porcher, C

Lack of truncated IFITM3 transcripts in cells homozygous for the rs12252-C variant that is associated with severe influenza infection অনুযায়ী Makvandi-Nejad, S, Laurenson-Schafer, H, Wang, L, Wellington, D, Zhao, Y, Jin, B, Qin, L, Kite, K, Moghadam, H, Song, C, Clark, K, Hublitz, P, Townsend, A, Wu, H, McMichael, A, Zhang, Y, Dong, T

Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia অনুযায়ী Mettananda, S, Fisher, C, Hay, D, Badat, M, Quek, L, Clark, K, Hublitz, P, Downes, D, Kerry, J, Gosden, M, Telenius, J, Sloane-Stanley, J, Faustino, P, Coelho, A, Doondeea, J, Usukhbayar, B, Sopp, P, Sharpe, J, Hughes, J, Vyas, P, Gibbons, R, Higgs, D

Colonic epithelial cell diversity in health and inflammatory bowel disease অনুযায়ী Parikh, K, Antanaviciute, AA, Fawkner-Corbett, D, Jagielowicz, M, Aulicino, A, Lagerholm, C, Davis, S, Kinchen, J, Chen, HH, Alham, N, Ashley, N, Johnson, E, Hublitz, P, Bao, L, Lukomska, J, Andev, R, Bjorklund, E, Kessler, BM, Fischer, R, Goldin, R, Koohy, H, Simmons, A

FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency অনুযায়ী Rota, I, Handel, A, Maio, S, Klein, F, Dhalla, F, Deadman, M, Cheuk, S, Newman, J, Michaels, Y, Zuklys, S, Prevot, N, Hublitz, P, Charles, P, Gkazi, A, Adamopoulou, E, Quasim, W, Davies, EG, Hanson, C, Pagnamenta, A, Camps, C, Dreau, H, White, A, James, K, Fischer, R, Gileadi, O, Taylor, J, Fulga, T, Lagerholm, BC, Anderson, G, Sezgin, E, Hollander, G

Evaluation of T cell responses to naturally processed variant SARS-CoV-2 spike antigens in individuals following infection or vaccination. অনুযায়ী Yin, Z, Chen, J-L, Lu, Y, Wang, B, Godfrey, L, Mentzer, AJ, Yao, X, Liu, G, Wellington, D, Zhao, Y, Wing, PAC, Dejnirattisa, W, Supasa, P, Liu, C, Hublitz, P, Beveridge, R, Waugh, C, Clark, S-A, Clark, K, Sopp, P, Rostron, T, Mongkolsapaya, J, Screaton, GR, Ogg, G, Ewer, K, Pollard, AJ, Gilbert, S, Knight, JC, Lambe, T, Smith, GL, Dong, T, Peng, Y

An immunodominant NP105–113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease অনুযায়ী Peng, Y, Felce, SL, Dong, D, Penkava, F, Mentzer, AJ, Yao, X, Liu, G, Yin, Z, Chen, J-L, Lu, Y, Wellington, D, Wing, PAC, Dominey-Foy, DCC, Jin, C, Wang, W, Hamid, MA, Fernandes, RA, Wang, B, Fries, A, Zhuang, X, Ashley, N, Rostron, T, Waugh, C, Sopp, P, Hublitz, P, Beveridge, R, Tan, TK, Dold, C, Kwok, AJ, Rich-Griffin, C, Dejnirattisa, W, Liu, C, Kurupati, P, Nassiri, I, Watson, RA, Tong, O, Taylor, CA, Kumar Sharma, P, Sun, B, Curion, F, Revale, S, Garner, LC, Jansen, K, Ferreira, RC, Attar, M, Fry, JW, Russell, RA, Stauss, HJ, James, W, Townsend, A, Ho, L-P, Klenerman , P, Mongkolsapaya , P, Screaton, GR, Dendrou, C, Sansom , SN, Bashford-Rogers, R, Chain , B, Smith , GL, McKeating, JA, Fairfax, BP, Bowness , P, McMichael, AJ, Ogg, G, Knight, JC, Dong, T