Genetic abrogation of immune checkpoints in antigen-specific cytotoxic T-lymphocyte as a potential alternative to blockade immunotherapy by Zhang, C, Peng, Y, Hublitz, P, Zhang, H, Dong, T

Rapid emergence of chronic lymphocytic leukemia during JAK2 inhibitor therapy in a patient with myelofibrosis by Sousos, N, Buck, G, Rodriguez-Meira, A, Norfo, R, Hamblin, A, Pezzella, F, Davies, J, Hublitz, P, Psaila, B, Mead, AJ

Infection with a Brazilian isolate of Zika virus generates RIG‐I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signalling by Hertzog, J, Dias, A, Rigby, R, Donald, C, Mayer, A, Sezgin, E, Song, C, Jin, B, Hublitz, P, Eggeling, C, Kohl, A, Rehwinkel, J

Autophagy-dependent generation of free fatty acids is critical for normal neutrophil differentiation by Riffelmacher, T, Clarke, A, Richter, F, Stranks, A, Pandey, S, Danielli, S, Hublitz, P, Yu, Z, Johnson, E, Schwerd, T, McCullagh, J, Uhlig, H, Jacobsen, S, Simon, A

Microhomologies are prevalent at Cas9-induced larger deletions by Owens, D, Caulder, A, Frontera, V, Harman, J, Allan, A, Bucakci, A, Greder, L, Codner, G, Hublitz, P, McHugh, P, Teboul, L, De Bruijn, M

Polyamines control eIF5A hypusination, TFEB translation, and autophagy to reverse B cell senescence by Zhang, H, Alsaleh, G, Feltham, J, Sun, Y, Napolitano, G, Riffelmacher, T, Charles, P, Frau, L, Hublitz, P, Yu, Z, Mohammed, S, Ballabio, A, Balabanov, S, Mellor, J, Simon, A

SARS-CoV-2 mutations affect antigen processing by the proteasome to alter CD8+ T cell responses by Wellington, D, Yin, Z, Yu, Z, Heilig, R, Davis, S, Fischer, R, Felce, SL, Antoun, E, Hublitz, P, Beveridge, R, Dong, D, Liu, G, Yao, X, Peng, Y, Kessler, B, Dong, T

Dual RNA sequencing reveals dendritic cell reprogramming in response to typhoidal Salmonella invasion by Aulicino, A, Antanaviciute, A, Frost, J, Sousa Geros, A, Mellado, E, Attar, M, Jagielowicz, M, Hublitz, P, Sinz, J, Preciado-Llanes, L, Napolitani, G, Bowden, R, Koohy, H, Drakesmith, AH, Simmons, A

GTP cyclohydrolase drives breast cancer development and promotes EMT in an enzyme-independent manner by Wang, Z, Zhang, N, Zhang, M, Jiang, Y, Fischer, R, Ng, AS, Bridges, E, Zhang, W, Zeng, X, Luo, Q, Liang, J, Győrffy, B, Hublitz, P, Liang, Z, Kerr, D, Harris, AL, Cai, S

SCL/TAL1 cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells by Chagraoui, H, Kristiansen, MS, Ruiz, JP, Serra-Barros, A, Richter, J, Hall-Ponselé, E, Gray, N, Waithe, D, Clark, K, Hublitz, P, Repapi, E, Otto, G, Sopp, P, Taylor, S, Thongjuea, S, Vyas, P, Porcher, C

Lack of truncated IFITM3 transcripts in cells homozygous for the rs12252-C variant that is associated with severe influenza infection by Makvandi-Nejad, S, Laurenson-Schafer, H, Wang, L, Wellington, D, Zhao, Y, Jin, B, Qin, L, Kite, K, Moghadam, H, Song, C, Clark, K, Hublitz, P, Townsend, A, Wu, H, McMichael, A, Zhang, Y, Dong, T

Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia by Mettananda, S, Fisher, C, Hay, D, Badat, M, Quek, L, Clark, K, Hublitz, P, Downes, D, Kerry, J, Gosden, M, Telenius, J, Sloane-Stanley, J, Faustino, P, Coelho, A, Doondeea, J, Usukhbayar, B, Sopp, P, Sharpe, J, Hughes, J, Vyas, P, Gibbons, R, Higgs, D

Colonic epithelial cell diversity in health and inflammatory bowel disease by Parikh, K, Antanaviciute, AA, Fawkner-Corbett, D, Jagielowicz, M, Aulicino, A, Lagerholm, C, Davis, S, Kinchen, J, Chen, HH, Alham, N, Ashley, N, Johnson, E, Hublitz, P, Bao, L, Lukomska, J, Andev, R, Bjorklund, E, Kessler, BM, Fischer, R, Goldin, R, Koohy, H, Simmons, A

FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency by Rota, I, Handel, A, Maio, S, Klein, F, Dhalla, F, Deadman, M, Cheuk, S, Newman, J, Michaels, Y, Zuklys, S, Prevot, N, Hublitz, P, Charles, P, Gkazi, A, Adamopoulou, E, Quasim, W, Davies, EG, Hanson, C, Pagnamenta, A, Camps, C, Dreau, H, White, A, James, K, Fischer, R, Gileadi, O, Taylor, J, Fulga, T, Lagerholm, BC, Anderson, G, Sezgin, E, Hollander, G

Evaluation of T cell responses to naturally processed variant SARS-CoV-2 spike antigens in individuals following infection or vaccination. by Yin, Z, Chen, J-L, Lu, Y, Wang, B, Godfrey, L, Mentzer, AJ, Yao, X, Liu, G, Wellington, D, Zhao, Y, Wing, PAC, Dejnirattisa, W, Supasa, P, Liu, C, Hublitz, P, Beveridge, R, Waugh, C, Clark, S-A, Clark, K, Sopp, P, Rostron, T, Mongkolsapaya, J, Screaton, GR, Ogg, G, Ewer, K, Pollard, AJ, Gilbert, S, Knight, JC, Lambe, T, Smith, GL, Dong, T, Peng, Y

An immunodominant NP105–113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease by Peng, Y, Felce, SL, Dong, D, Penkava, F, Mentzer, AJ, Yao, X, Liu, G, Yin, Z, Chen, J-L, Lu, Y, Wellington, D, Wing, PAC, Dominey-Foy, DCC, Jin, C, Wang, W, Hamid, MA, Fernandes, RA, Wang, B, Fries, A, Zhuang, X, Ashley, N, Rostron, T, Waugh, C, Sopp, P, Hublitz, P, Beveridge, R, Tan, TK, Dold, C, Kwok, AJ, Rich-Griffin, C, Dejnirattisa, W, Liu, C, Kurupati, P, Nassiri, I, Watson, RA, Tong, O, Taylor, CA, Kumar Sharma, P, Sun, B, Curion, F, Revale, S, Garner, LC, Jansen, K, Ferreira, RC, Attar, M, Fry, JW, Russell, RA, Stauss, HJ, James, W, Townsend, A, Ho, L-P, Klenerman , P, Mongkolsapaya , P, Screaton, GR, Dendrou, C, Sansom , SN, Bashford-Rogers, R, Chain , B, Smith , GL, McKeating, JA, Fairfax, BP, Bowness , P, McMichael, AJ, Ogg, G, Knight, JC, Dong, T