A High-Dimensional Window into the Micro-Environment of Triple Negative Breast Cancer by Iris Nederlof, Hugo M. Horlings, Christina Curtis, Marleen Kok

Get full text

Low grade serous carcinoma of the peritoneum in a BRCA1 carrier previously diagnosed with a “low-grade serous tubal intra-epithelial carcinoma” (STIC) on risk reducing surgery by Wen Yee Chay, Hugo M. Horlings, Anna V. Tinker, Karen A. Gelmon, C.Blake Gilks

Get full text

Integration of clinical and gene expression data has a synergetic effect on predicting breast cancer outcome. by Martin H van Vliet, Hugo M Horlings, Marc J van de Vijver, Marcel J T Reinders, Lodewyk F A Wessels

Get full text

Spatial interplay of tissue hypoxia and T-cell regulation in ductal carcinoma in situ by Faranak Sobhani, Sathya Muralidhar, Azam Hamidinekoo, Allison H. Hall, Lorraine M. King, Jeffrey R. Marks, Carlo Maley, Hugo M. Horlings, E. Shelley Hwang, Yinyin Yuan

Get full text

Immune landscape of breast tumors with low and intermediate estrogen receptor expression by Leonie Voorwerk, Joyce Sanders, Milou S. Keusters, Sara Balduzzi, Sten Cornelissen, Maxime Duijst, Esther H. Lips, Gabe S. Sonke, Sabine C. Linn, Hugo M. Horlings, Marleen Kok

Get full text

Predicting breast cancer types on and beyond molecular level in a multi-modal fashion by Tianyu Zhang, Tao Tan, Luyi Han, Linda Appelman, Jeroen Veltman, Ronni Wessels, Katya M. Duvivier, Claudette Loo, Yuan Gao, Xin Wang, Hugo M. Horlings, Regina G. H. Beets-Tan, Ritse M. Mann

Get full text

External validation of Adjuvant! Online breast cancer prognosis tool. Prioritising recommendations for improvement. by David Hajage, Yann de Rycke, Marc Bollet, Alexia Savignoni, Martial Caly, Jean-Yves Pierga, Hugo M Horlings, Marc J Van de Vijver, Anne Vincent-Salomon, Brigitte Sigal-Zafrani, Claire Senechal, Bernard Asselain, Xavier Sastre, Fabien Reyal

Get full text

PROACTING: predicting pathological complete response to neoadjuvant chemotherapy in breast cancer from routine diagnostic histopathology biopsies with deep learning by Witali Aswolinskiy, Enrico Munari, Hugo M. Horlings, Lennart Mulder, Giuseppe Bogina, Joyce Sanders, Yat-Hee Liu, Alexandra W. van den Belt-Dusebout, Leslie Tessier, Maschenka Balkenhol, Michelle Stegeman, Jeffrey Hoven, Jelle Wesseling, Jeroen van der Laak, Esther H. Lips, Francesco Ciompi

Get full text

Deep learning for fully-automated nuclear pleomorphism scoring in breast cancer by Caner Mercan, Maschenka Balkenhol, Roberto Salgado, Mark Sherman, Philippe Vielh, Willem Vreuls, António Polónia, Hugo M. Horlings, Wilko Weichert, Jodi M. Carter, Peter Bult, Matthias Christgen, Carsten Denkert, Koen van de Vijver, John-Melle Bokhorst, Jeroen van der Laak, Francesco Ciompi

Get full text

Cancer-immune interactions in ER-positive breast cancers: PI3K pathway alterations and tumor-infiltrating lymphocytes by Marcelo Sobral-Leite, Izhar Salomon, Mark Opdam, Dinja T. Kruger, Karin J. Beelen, Vincent van der Noort, Ronald L. P. van Vlierberghe, Erik J. Blok, Daniele Giardiello, Joyce Sanders, Koen Van de Vijver, Hugo M. Horlings, Peter J. K. Kuppen, Sabine C. Linn, Marjanka K. Schmidt, Marleen Kok

Get full text

B-cells and regulatory T-cells in the microenvironment of HER2+ breast cancer are associated with decreased survival: a real-world analysis of women with HER2+ metastatic breast ca... by Tessa G. Steenbruggen, Denise M. Wolf, Michael J. Campbell, Joyce Sanders, Sten Cornelissen, Bram Thijssen, Roberto A. Salgado, Christina Yau, Nick O-Grady, Amrita Basu, Rajith Bhaskaran, Lorenza Mittempergher, Gillian L. Hirst, Jean-Philippe Coppe, Marleen Kok, Gabe S. Sonke, Laura J. van ‘t Veer, Hugo M. Horlings

Get full text

IHC-based Ki67 as response biomarker to tamoxifen in breast cancer window trials enrolling premenopausal women by Stacey E. P. Joosten, Marius Wellenstein, Rutger Koornstra, Annelot van Rossum, Joyce Sanders, Vincent van der Noort, Maria C. Ferrandez, Rolf Harkes, Ingrid A. M. Mandjes, Hilde Rosing, Alwin Huitema, Jos H. Beijnen, Jelle Wesseling, Paul J. van Diest, Hugo M. Horlings, Sabine C. Linn, Wilbert Zwart

Get full text

Adult‐type granulosa cell tumor of the ovary: a FOXL2‐centric disease by Jessica A Pilsworth, Dawn R Cochrane, Samantha J Neilson, Bahar H Moussavi, Daniel Lai, Aslı D Munzur, Janine Senz, Yi Kan Wang, Sina Zareian, Ali Bashashati, Adele Wong, Jacqueline Keul, Annette Staebler, Hannah S vanMeurs, Hugo M Horlings, Stefan Kommoss, Friedrich Kommoss, Esther Oliva, Anniina EM Färkkilä, Blake Gilks, David G Huntsman

Get full text

Author Correction: Reversal of pre-existing NGFR-driven tumor and immune therapy resistance by Julia Boshuizen, David W. Vredevoogd, Oscar Krijgsman, Maarten A. Ligtenberg, Stephanie Blankenstein, Beaunelle de Bruijn, Dennie T. Frederick, Juliana C. N. Kenski, Mara Parren, Marieke Brüggemann, Max F. Madu, Elisa A. Rozeman, Ji-Ying Song, Hugo M. Horlings, Christian U. Blank, Alexander C. J. van Akkooi, Keith T. Flaherty, Genevieve M. Boland, Daniel S. Peeper

Get full text

Comprehensive evaluation of methods to assess overall and cell-specific immune infiltrates in breast cancer by Iris Nederlof, Davide De Bortoli, Yacine Bareche, Bastien Nguyen, Michiel de Maaker, Gerrit K. J. Hooijer, Laurence Buisseret, Marleen Kok, Marcel Smid, Gert G. G. M. Van den Eynden, Arie B. Brinkman, Jan Hudecek, Jan Koster, Christos Sotiriou, Denis Larsimont, John W. M. Martens, Marc J. van de Vijver, Hugo M. Horlings, Roberto Salgado, Elia Biganzoli, Christine Desmedt

Get full text

Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers by Tom Van Nyen, Mélanie Planque, Lilian van Wagensveld, Joao A. G. Duarte, Esther A. Zaal, Ali Talebi, Matteo Rossi, Pierre-René Körner, Lara Rizzotto, Stijn Moens, Wout De Wispelaere, Regina E. M. Baiden-Amissah, Gabe S. Sonke, Hugo M. Horlings, Guy Eelen, Emanuele Berardi, Johannes V. Swinnen, Celia R. Berkers, Peter Carmeliet, Diether Lambrechts, Ben Davidson, Reuven Agami, Sarah-Maria Fendt, Daniela Annibali, Frédéric Amant

Get full text

Assessment of PD-L1 expression across breast cancer molecular subtypes, in relation to mutation rate, BRCA1-like status, tumor-infiltrating immune cells and survival by Marcelo Sobral-Leite, Koen Van de Vijver, Magali Michaut, Rianne van der Linden, Gerrit K.J. Hooijer, Hugo M. Horlings, Tesa M. Severson, Anna Marie Mulligan, Nayana Weerasooriya, Joyce Sanders, Annuska M Glas, Diederik Wehkamp, Lorenza Mittempergher, Kelly Kersten, Ashley Cimino-Mathews, Dennis Peters, Erik Hooijberg, Annegien Broeks, Marc J. van de Vijver, Rene Bernards, Irene L. Andrulis, Marleen Kok, Karin E. de Visser, Marjanka K. Schmidt

Get full text

Homologous Recombination Deficiency and Cyclin E1 Amplification Are Correlated with Immune Cell Infiltration and Survival in High-Grade Serous Ovarian Cancer by Lilian van Wagensveld, Juliette O. A. M. van Baal, Maite Timmermans, Duco Gaillard, Lauri Borghuis, Seth B. Coffelt, Efraim H. Rosenberg, Christianne A. R. Lok, Hans W. Nijman, Loes F. S. Kooreman, Joyce Sanders, Marco de Bruijn, Lodewyk F. A. Wessels, Rianne van der Wiel, Christian Rausch, Annegien Broeks, Roy F. P. M. Kruitwagen, Maaike A. van der Aa, Gabe S. Sonke, Philip C. Schouten, Koen K. Van de Vijver, Hugo M. Horlings

Get full text