MicroRNA-7 regulates melanocortin circuits involved in mammalian energy homeostasis by Mary P. LaPierre, Katherine Lawler, Svenja Godbersen, I. Sadaf Farooqi, Markus Stoffel

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Visualization of sympathetic neural innervation in human white adipose tissue by Aliki Perdikari, Tessa Cacciottolo, Elana Henning, Edson Mendes de Oliveira, Julia M. Keogh, I. Sadaf Farooqi

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Oxytocin administration suppresses hypothalamic activation in response to visual food cues by Agatha A. van der Klaauw, Hisham Ziauddeen, Julia M. Keogh, Elana Henning, Sekesai Dachi, Paul C. Fletcher, I. Sadaf Farooqi

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Predicting novel candidate human obesity genes and their site of action by systematic functional screening in Drosophila by Neha Agrawal, Katherine Lawler, Catherine M. Davidson, Julia M. Keogh, Robert Legg, INTERVAL, Inês Barroso, I. Sadaf Farooqi, Andrea H. Brand

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Sequence variants in the melatonin-related receptor gene (GPR50) associate with circulating triglyceride and HDL levels by Sumit Bhattacharyya, Jian'an Luan, Benjamin Challis, Julia Keogh, Carl Montague, John Brennand, John Morten, Sarah Lowenbeim, Suzanne Jenkins, I. Sadaf Farooqi, Nicholas J. Wareham, Stephen O'Rahilly

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Divergent effects of central melanocortin signalling on fat and sucrose preference in humans by Agatha A. van der Klaauw, Julia M. Keogh, Elana Henning, Cheryl Stephenson, Sarah Kelway, Victoria M. Trowse, Naresh Subramanian, Stephen O’Rahilly, Paul C. Fletcher, I. Sadaf Farooqi

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Neural networks associated with body composition in frontotemporal dementia by Rebekah M. Ahmed, Ramon Landin‐Romero, Cheng T. Liang, Julia M. Keogh, Elana Henning, Cherie Strikwerda‐Brown, Emma M. Devenney, John R. Hodges, Matthew C. Kiernan, I. Sadaf Farooqi, Olivier Piguet

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A Transcriptomic Signature of the Hypothalamic Response to Fasting and BDNF Deficiency in Prader-Willi Syndrome by Elena G. Bochukova, Katherine Lawler, Sophie Croizier, Julia M. Keogh, Nisha Patel, Garth Strohbehn, Kitty K. Lo, Jack Humphrey, Anita Hokken-Koelega, Layla Damen, Stephany Donze, Sebastien G. Bouret, Vincent Plagnol, I. Sadaf Farooqi

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Quantitative mass spectrometry for human melanocortin peptides in vitro and in vivo suggests prominent roles for β-MSH and desacetyl α-MSH in energy homeostasis by Peter Kirwan, Richard G. Kay, Bas Brouwers, Vicente Herranz-Pérez, Magdalena Jura, Pierre Larraufie, Julie Jerber, Jason Pembroke, Theresa Bartels, Anne White, Fiona M. Gribble, Frank Reimann, I. Sadaf Farooqi, Stephen O'Rahilly, Florian T. Merkle

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Genetic architecture of human thinness compared to severe obesity. by Fernando Riveros-McKay, Vanisha Mistry, Rebecca Bounds, Audrey Hendricks, Julia M Keogh, Hannah Thomas, Elana Henning, Laura J Corbin, Understanding Society Scientific Group, Stephen O'Rahilly, Eleftheria Zeggini, Eleanor Wheeler, Inês Barroso, I Sadaf Farooqi

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Trappc9 deficiency causes parent-of-origin dependent microcephaly and obesity. by Zhengzheng S Liang, Irene Cimino, Binnaz Yalcin, Narayanan Raghupathy, Valerie E Vancollie, Ximena Ibarra-Soria, Helen V Firth, Debra Rimmington, I Sadaf Farooqi, Christopher J Lelliott, Steven C Munger, Stephen O'Rahilly, Anne C Ferguson-Smith, Anthony P Coll, Darren W Logan

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A rare human variant that disrupts GPR10 signalling causes weight gain in mice by Fleur Talbot, Claire H. Feetham, Jacek Mokrosiński, Katherine Lawler, Julia M. Keogh, Elana Henning, Edson Mendes de Oliveira, Vikram Ayinampudi, Sadia Saeed, Amélie Bonnefond, Mohammed Arslan, Giles S. H. Yeo, Philippe Froguel, David A. Bechtold, Antony Adamson, Neil Humphreys, Inês Barroso, Simon M. Luckman, I. Sadaf Farooqi

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Disruption of the homeodomain transcription factor orthopedia homeobox (Otp) is associated with obesity and anxiety by Lee Moir, Elena G. Bochukova, Rebecca Dumbell, Gareth Banks, Rasneer S. Bains, Patrick M. Nolan, Cheryl Scudamore, Michelle Simon, Kimberly A. Watson, Julia Keogh, Elana Henning, Audrey Hendricks, Stephen O'Rahilly, Inês Barroso, Adrienne E. Sullivan, David C. Bersten, Murray L. Whitelaw, Susan Kirsch, Elizabeth Bentley, I. Sadaf Farooqi, Roger D. Cox

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Murine neuronatin deficiency is associated with a hypervariable food intake and bimodal obesity by Irene Cimino, Debra Rimmington, Y. C. Loraine Tung, Katherine Lawler, Pierre Larraufie, Richard G. Kay, Samuel Virtue, Brian Y. H. Lam, Luca Fagnocchi, Marcella K. L. Ma, Vladimir Saudek, Ilona Zvetkova, Antonio Vidal-Puig, Giles S. H. Yeo, I. Sadaf Farooqi, J. Andrew Pospisilik, Fiona M. Gribble, Frank Reimann, Stephen O’Rahilly, Anthony P. Coll

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Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis by Yongjie Yang, Agatha A. van der Klaauw, Liangru Zhu, Tessa M. Cacciottolo, Yanlin He, Lukas K. J. Stadler, Chunmei Wang, Pingwen Xu, Kenji Saito, Antentor Hinton, Xiaofeng Yan, Julia M. Keogh, Elana Henning, Matthew C. Banton, Audrey E. Hendricks, Elena G. Bochukova, Vanisha Mistry, Katherine L. Lawler, Lan Liao, Jianming Xu, Stephen O’Rahilly, Qingchun Tong, UK10K Consortium, Inês Barroso, Bert W. O’Malley, I. Sadaf Farooqi, Yong Xu

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Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency by Tinh-Hai Collet, Béatrice Dubern, Jacek Mokrosinski, Hillori Connors, Julia M. Keogh, Edson Mendes de Oliveira, Elana Henning, Christine Poitou-Bernert, Jean-Michel Oppert, Patrick Tounian, Florence Marchelli, Rohia Alili, Johanne Le Beyec, Dominique Pépin, Jean-Marc Lacorte, Andrew Gottesdiener, Rebecca Bounds, Shubh Sharma, Cathy Folster, Bart Henderson, Stephen O'Rahilly, Elizabeth Stoner, Keith Gottesdiener, Brandon L. Panaro, Roger D. Cone, Karine Clément, I. Sadaf Farooqi, Lex H.T. Van der Ploeg

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OBEDIS Core Variables Project: European Expert Guidelines on a Minimal Core Set of Variables to Include in Randomized, Controlled Clinical Trials of Obesity Interventions by Maud Alligier, Romain Barrès, Ellen E. Blaak, Yves Boirie, Jildau Bouwman, Paul Brunault, Kristina Campbell, Karine Clément, I. Sadaf Farooqi, Nathalie J. Farpour-Lambert, Gema Frühbeck, Gijs H. Goossens, Jorg Hager, Jason C.G. Halford, Hans Hauner, David Jacobi, Chantal Julia, Dominique Langin, Andrea Natali, Martin Neovius, Jean Michel Oppert, Uberto Pagotto, Antonio L. Palmeira, Helen Roche, Mikael Rydén, André J. Scheen, Chantal Simon, Thorkild I.A. Sorensen, Luc Tappy, Hannele Yki-Järvinen, Olivier Ziegler, Martine Laville

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Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity by Audrey E. Hendricks, Elena G. Bochukova, Gaëlle Marenne, Julia M. Keogh, Neli Atanassova, Rebecca Bounds, Eleanor Wheeler, Vanisha Mistry, Elana Henning, Antje Körner, Dawn Muddyman, Shane McCarthy, Anke Hinney, Johannes Hebebrand, Robert A. Scott, Claudia Langenberg, Nick J. Wareham, Praveen Surendran, Joanna M. Howson, Adam S. Butterworth, John Danesh, Børge G Nordestgaard, Sune F Nielsen, Shoaib Afzal, Sofia Papadia, Sofie Ashford, Sumedha Garg, Glenn L. Millhauser, Rafael I. Palomino, Alexandra Kwasniewska, Ioanna Tachmazidou, Stephen O’Rahilly, Eleftheria Zeggini, Inês Barroso, I. Sadaf Farooqi, Understanding Society Scientific Group, EPIC-CVD Consortium, UK10K Consortium

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Atypical B cells and impaired SARS-CoV-2 neutralization following heterologous vaccination in the elderly by Isabella A.T.M. Ferreira, Colin Y.C. Lee, William S. Foster, Adam Abdullahi, Lisa M. Dratva, Zewen Kelvin Tuong, Benjamin J. Stewart, John R. Ferdinand, Stephane M. Guillaume, Martin O.P. Potts, Marianne Perera, Benjamin A. Krishna, Ana Peñalver, Mia Cabantous, Steven A. Kemp, Lourdes Ceron-Gutierrez, Soraya Ebrahimi, Paul Lyons, Kenneth G.C. Smith, John Bradley, Dami A. Collier, Laura E. McCoy, Agatha van der Klaauw, James E.D. Thaventhiran, I. Sadaf Farooqi, Sarah A. Teichmann, Paul A. MacAry, Rainer Doffinger, Mark R. Wills, Michelle A. Linterman, Menna R. Clatworthy, Ravindra K. Gupta

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