The challenges in data integration – heterogeneity and complexity in clinical trials and patient registries of Systemic Lupus Erythematosus by Helen Le Sueur, Ian N. Bruce, Nophar Geifman, on behalf of the MASTERPLANS Consortium

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High throughput multiplex immunoassays stratify patients according to symptom burden across the anti-Ro positive systemic autoimmune rheumatic disease spectrum by Sarah Dyball, Rudresh Shukla, Anastasia-Vasiliki Madenidou, Maya H. Buch, Ian N. Bruce, Ben Parker

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Lupus spectrum ambiguity has long-term negative implications for patients by Susan Manzi, Ian N Bruce, Sang-Cheol Bae, Sanjyot Sangodkar, Roger A Levy, Ashley Marion

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Lupus clinical trial eligibility in a real-world setting: results from the British Isles Lupus Assessment Group-Biologics Register (BILAG-BR) by Ian N Bruce, Eoghan M McCarthy, Ben Parker, Sarah Dyball, Sophie Collinson, Emily Sutton

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P124 High throughput multiplex immunoassays stratify patients according to symptom burden across the Lupus-Sjögren’s spectrum by Ian N Bruce, Ben Parker, Maya Buch, Anastasia-Vasiliki Madenidou, Sarah Dyball, Rudresh Shukla, Mia Rodziewicz

Distinct patterns of disease activity over time in patients with active SLE revealed using latent class trajectory models by John A. Reynolds, Jennifer Prattley, Nophar Geifman, Mark Lunt, Caroline Gordon, Ian N. Bruce, on behalf of the MASTERPLANS Consortium

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Efficacy of belimumab in two serologically distinct high disease activity subgroups of patients with systemic lupus erythematosus: post-hoc analysis of data from the phase III prog... by Ian N Bruce, Damon L Bass, David A Roth, Toni Maslen, David D'Cruz, Mihaela Ianosev, Christel Wilkinson

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Changes in the incidence and prevalence of systemic lupus erythematosus between 1990 and 2020: an observational study using the Clinical Practice Research Datalink (CPRD) by Sarah Skeoch, Ian N Bruce, John D Pauling, Neil McHugh, Jessica Ellis, Anita McGrogan, Rachel Charlton

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Urine and serum S100A8/A9 and S100A12 associate with active lupus nephritis and may predict response to rituximab treatment by Ian N Bruce, Christian M Hedrich, Michael W Beresford, Jennifer C Davies, Angela Midgley, Emil Carlsson, Sean Donohue

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Letter in reply: indirect treatment comparison of anifrolumab efficacy versus belimumab in adults with systemic lupus erythematosus by Ian N Bruce, Sarowar Golam, Jason Steenkamp, Pearl Wang, Evelyn Worthington, Barnabas Desta, Konstantina Psachoulia, Wilma Erhardt, Raj Tummala

Symptoms in first-degree relatives of patients with rheumatoid arthritis: evaluation of cross-sectional data from the symptoms in persons at risk of rheumatoid arthritis (SPARRA) q... by R. E. Costello, J. H. Humphreys, J. C. Sergeant, M. Haris, F. Stirling, K. Raza, D. van Schaardenburg, Ian N. Bruce

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Immune gene expression and functional networks in distinct lupus nephritis classes by Ian N Bruce, Liz Lightstone, Marina Botto, Alyssa C Gilmore, Hannah R Wilson, Thomas D Cairns, Herbert Terence Cook, Matthew Caleb Pickering

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Cytokine profiling in active and quiescent SLE reveals distinct patient subpopulations by John A. Reynolds, Eoghan M. McCarthy, Sahena Haque, Pintip Ngamjanyaporn, Jamie C. Sergeant, Elaine Lee, Eileen Lee, Stephen A. Kilfeather, Ben Parker, Ian N. Bruce

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Correction: Targeting DORIS Remission and LLDAS in SLE: A Review by Agner R. Parra Sánchez, Ronald F. van Vollenhoven, Eric F. Morand, Ian N. Bruce, Rangi Kandane-Rathnayake, Gudrun Weiss, Raj Tummala, Hussein Al-Mossawi, Alessandro Sorrentino

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Targeting DORIS Remission and LLDAS in SLE: A Review by Agner R. Parra Sánchez, Ronald F. van Vollenhoven, Eric F. Morand, Ian N. Bruce, Rangi Kandane-Rathnayake, Gudrun Weiss, Raj Tummala, Hussein Al-Mossawi, Alessandro Sorrentino

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Novel Glycomimetics Protect against Glycated Low-Density Lipoprotein-Induced Vascular Calcification In Vitro via Attenuation of the RAGE/ERK/CREB Pathway by Gary P. Sidgwick, Ria Weston, Ayman M. Mahmoud, Andrew Schiro, Ferdinand Serracino-Inglott, Shikha M. Tandel, Sarah Skeoch, Ian N. Bruce, Alan M. Jones, M. Yvonne Alexander, Fiona L. Wilkinson

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Conceptual framework for defining disease modification in systemic lupus erythematosus: a call for formal criteria by Richard Furie, Ian N Bruce, Ronald van Vollenhoven, Maria Dall'Era, Andreas Schwarting, Ming-hui Zhao, Anca D Askanase, Roger A Levy, Mark Daniels, Andrew S Bomback, Angela Carroll, Holly A Quasny

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Deconvolution of whole blood transcriptomics identifies changes in immune cell composition in patients with systemic lupus erythematosus (SLE) treated with mycophenolate mofetil by Mumina Akthar, Nisha Nair, Lucy M. Carter, Edward M. Vital, Emily Sutton, Neil McHugh, British Isles Lupus Assessment Group Biologics Register (BILAG BR) Consortium, MASTERPLANS Consortium, Ian N. Bruce, John A. Reynolds

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Disease-modifying therapies in systemic lupus erythematosus for extrarenal manifestations by Munther Khamashta, Richard A Furie, Ian N Bruce, Ronald van Vollenhoven, Murray B Urowitz, Andreas Schwarting, Ming-hui Zhao, Anca D Askanase, Mark Daniels, Andrew S Bomback, Angela Carroll, Bernie Rubin, Roger Abramino Levy

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Rheumatoid arthritis reprograms circadian output pathways by Toryn M. Poolman, Julie Gibbs, Amy L. Walker, Suzanna Dickson, Laura Farrell, James Hensman, Alexandra C. Kendall, Robert Maidstone, Stacey Warwood, Andrew Loudon, Magnus Rattray, Ian N. Bruce, Anna Nicolaou, David W. Ray

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