Connecting the Dots: Resolving the Bone Marrow Niche Heterogeneity by Igor Dolgalev, Anastasia N. Tikhonova

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DangerTrack: A scoring system to detect difficult-to-assess regions [version 1; referees: 2 approved, 1 approved with reservations] by Igor Dolgalev, Fritz Sedlazeck, Ben Busby

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Both fallopian tube and ovarian surface epithelium are cells-of-origin for high-grade serous ovarian carcinoma by Shuang Zhang, Igor Dolgalev, Tao Zhang, Hao Ran, Douglas A. Levine, Benjamin G. Neel

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Functional genomic analysis identifies indoxyl sulfate as a major, poorly dialyzable uremic toxin in end-stage renal disease. by Sachin Jhawar, Prabhjot Singh, Daniel Torres, Francisco Ramirez-Valle, Hania Kassem, Trina Banerjee, Igor Dolgalev, Adriana Heguy, Jiri Zavadil, Jerome Lowenstein

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Correction: The fecal, oral, and skin microbiota of children with Chagas disease treated with benznidazole. by Carlos Robello, Doris Patricia Maldonado, Anna Hevia, Marina Hoashi, Paola Frattaroli, Valentina Montacutti, Adriana Heguy, Igor Dolgalev, Maricruz Mojica, Gregorio Iraola, Maria G Dominguez-Bello

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The fecal, oral, and skin microbiota of children with Chagas disease treated with benznidazole. by Carlos Robello, Doris Patricia Maldonado, Anna Hevia, Marina Hoashi, Paola Frattaroli, Valentina Montacutti, Adriana Heguy, Igor Dolgalev, Maricruz Mojica, Gregorio Iraola, Maria G Dominguez-Bello

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POLQ inhibition elicits an immune response in homologous recombination–deficient pancreatic adenocarcinoma via cGAS/STING signaling by Grace Oh, Annie Wang, Lidong Wang, Jiufeng Li, Gregor Werba, Daniel Weissinger, Ende Zhao, Surajit Dhara, Rosmel E. Hernandez, Amanda Ackermann, Sarina Porcella, Despoina Kalfakakou, Igor Dolgalev, Emily Kawaler, Talia Golan, Theodore H. Welling, Agnel Sfeir, Diane M. Simeone

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An epigenetic switch controls an alternative NR2F2 isoform that unleashes a metastatic program in melanoma by Veronica Davalos, Claudia D. Lovell, Richard Von Itter, Igor Dolgalev, Praveen Agrawal, Gillian Baptiste, David J. Kahler, Elena Sokolova, Sebastian Moran, Laia Piqué, Eleazar Vega-Saenz de Miera, Barbara Fontanals-Cirera, Alcida Karz, Aristotelis Tsirigos, Chi Yun, Farbod Darvishian, Heather C. Etchevers, Iman Osman, Manel Esteller, Markus Schober, Eva Hernando

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Single-cell RNA sequencing reveals the effects of chemotherapy on human pancreatic adenocarcinoma and its tumor microenvironment by Gregor Werba, Daniel Weissinger, Emily A. Kawaler, Ende Zhao, Despoina Kalfakakou, Surajit Dhara, Lidong Wang, Heather B. Lim, Grace Oh, Xiaohong Jing, Nina Beri, Lauren Khanna, Tamas Gonda, Paul Oberstein, Cristina Hajdu, Cynthia Loomis, Adriana Heguy, Mara H. Sherman, Amanda W. Lund, Theodore H. Welling, Igor Dolgalev, Aristotelis Tsirigos, Diane M. Simeone

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Modulating mitofusins to control mitochondrial function and signaling by Emmanouil Zacharioudakis, Bogos Agianian, Vasantha Kumar MV, Nikolaos Biris, Thomas P. Garner, Inna Rabinovich-Nikitin, Amanda T. Ouchida, Victoria Margulets, Lars Ulrik Nordstrøm, Joel S. Riley, Igor Dolgalev, Yun Chen, Andre J. H. Wittig, Ryan Pekson, Chris Mathew, Peter Wei, Aristotelis Tsirigos, Stephen W. G. Tait, Lorrie A. Kirshenbaum, Richard N. Kitsis, Evripidis Gavathiotis

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Author Correction: Single-cell RNA sequencing reveals the effects of chemotherapy on human pancreatic adenocarcinoma and its tumor microenvironment by Gregor Werba, Daniel Weissinger, Emily A. Kawaler, Ende Zhao, Despoina Kalfakakou, Surajit Dhara, Lidong Wang, Heather B. Lim, Grace Oh, Xiaohong Jing, Nina Beri, Lauren Khanna, Tamas Gonda, Paul Oberstein, Cristina Hajdu, Cynthia Loomis, Adriana Heguy, Mara H. Sherman, Amanda W. Lund, Theodore H. Welling, Igor Dolgalev, Aristotelis Tsirigos, Diane M. Simeone

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Oxidized mC modulates synthetic lethality to PARP inhibitors for the treatment of leukemia by John P. Brabson, Tiffany Leesang, Yoon Sing Yap, Jingjing Wang, Minh Q. Lam, Byron Fang, Igor Dolgalev, Daniela A. Barbieri, Victoria Strippoli, Carolina P. Bañuelos, Sofia Mohammad, Peter Lyon, Sana Chaudhry, Dane Donich, Anna Swirski, Evan Roberts, Ivelisse Diaz, Daniel Karl, Helena Gomes Dos Santos, Ramin Shiekhattar, Benjamin G. Neel, Stephen D. Nimer, Ramiro E. Verdun, Daniel Bilbao, Maria E. Figueroa, Luisa Cimmino

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SPOP Mutations in Prostate Cancer across Demographically Diverse Patient Cohorts by Mirjam Blattner, Daniel J. Lee, Catherine O'Reilly, Kyung Park, Theresa Y. MacDonald, Francesca Khani, Kevin R. Turner, Ya-Lin Chiu, Peter J. Wild, Igor Dolgalev, Adriana Heguy, Andrea Sboner, Sinan Ramazangolu, Haley Hieronymus, Charles Sawyers, Ashutosh K. Tewari, Holger Moch, Ghil Suk Yoon, Yong Chul Known, Ove Andrén, Katja Fall, Francecsa Demichelis, Juan Miguel Mosquera, Brian D. Robinson, Christopher E. Barbieri, Mark A. Rubin

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Plakophilin-2 is required for transcription of genes that control calcium cycling and cardiac rhythm by Marina Cerrone, Jerome Montnach, Xianming Lin, Yan-Ting Zhao, Mingliang Zhang, Esperanza Agullo-Pascual, Alejandra Leo-Macias, Francisco J. Alvarado, Igor Dolgalev, Thomas V. Karathanos, Kabir Malkani, Chantal J.M. Van Opbergen, Joanne J.A. van Bavel, Hua-Qian Yang, Carolina Vasquez, David Tester, Steven Fowler, Fengxia Liang, Eli Rothenberg, Adriana Heguy, Gregory E. Morley, William A. Coetzee, Natalia A. Trayanova, Michael J. Ackerman, Toon A.B. van Veen, Hector H. Valdivia, Mario Delmar

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Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma by Matija Snuderl, Kasthuri Kannan, Elke Pfaff, Shiyang Wang, James M. Stafford, Jonathan Serrano, Adriana Heguy, Karina Ray, Arline Faustin, Olga Aminova, Igor Dolgalev, Stacie L. Stapleton, David Zagzag, Luis Chiriboga, Sharon L. Gardner, Jeffrey H. Wisoff, John G. Golfinos, David Capper, Volker Hovestadt, Marc K. Rosenblum, Dimitris G. Placantonakis, Sarah E. LeBoeuf, Thales Y. Papagiannakopoulos, Lukas Chavez, Sama Ahsan, Charles G. Eberhart, Stefan M. Pfister, David T. W. Jones, Matthias A. Karajannis

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Inflammation in the tumor-adjacent lung as a predictor of clinical outcome in lung adenocarcinoma by Igor Dolgalev, Hua Zhou, Nina Murrell, Hortense Le, Theodore Sakellaropoulos, Nicolas Coudray, Kelsey Zhu, Varshini Vasudevaraja, Anna Yeaton, Chandra Goparaju, Yonghua Li, Imran Sulaiman, Jun-Chieh J. Tsay, Peter Meyn, Hussein Mohamed, Iris Sydney, Tomoe Shiomi, Sitharam Ramaswami, Navneet Narula, Ruth Kulicke, Fred P. Davis, Nicolas Stransky, Gromoslaw A. Smolen, Wei-Yi Cheng, James Cai, Salman Punekar, Vamsidhar Velcheti, Daniel H. Sterman, J. T. Poirier, Ben Neel, Kwok-Kin Wong, Luis Chiriboga, Adriana Heguy, Thales Papagiannakopoulos, Bettina Nadorp, Matija Snuderl, Leopoldo N. Segal, Andre L. Moreira, Harvey I. Pass, Aristotelis Tsirigos

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A pan-cancer organoid platform for precision medicine by Brian M. Larsen, Madhavi Kannan, Lee F. Langer, Benjamin D. Leibowitz, Aicha Bentaieb, Andrea Cancino, Igor Dolgalev, Bridgette E. Drummond, Jonathan R. Dry, Chi-Sing Ho, Gaurav Khullar, Benjamin A. Krantz, Brandon Mapes, Kelly E. McKinnon, Jessica Metti, Jason F. Perera, Tim A. Rand, Veronica Sanchez-Freire, Jenna M. Shaxted, Michelle M. Stein, Michael A. Streit, Yi-Hung Carol Tan, Yilin Zhang, Ende Zhao, Jagadish Venkataraman, Martin C. Stumpe, Jeffrey A. Borgia, Ashiq Masood, Daniel V.T. Catenacci, Jeremy V. Mathews, Demirkan B. Gursel, Jian-Jun Wei, Theodore H. Welling, Diane M. Simeone, Kevin P. White, Aly A. Khan, Catherine Igartua, Ameen A. Salahudeen

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