Purification of full-length recombinant human huntingtin proteins with allelic series of polyglutamine lengths by Hyeongju Kim, Kyung-gi Hyun, Alejandro Lloret, Ihn Sik Seong, Ji-Joon Song

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Unbiased gene expression analysis implicates the huntingtin polyglutamine tract in extra-mitochondrial energy metabolism. by Jong-Min Lee, Elena V Ivanova, Ihn Sik Seong, Tanya Cashorali, Isaac Kohane, James F Gusella, Marcy E MacDonald

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Allele-specific silencing of the gain-of-function mutation in Huntington’s disease using CRISPR/Cas9 by Jun Wan Shin, Eun Pyo Hong, Seri S. Park, Doo Eun Choi, Ihn Sik Seong, Madelynn N. Whittaker, Benjamin P. Kleinstiver, Richard Z. Chen, Jong-Min Lee

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Huntingtin’s spherical solenoid structure enables polyglutamine tract-dependent modulation of its structure and function by Ravi Vijayvargia, Raquel Epand, Alexander Leitner, Tae-Yang Jung, Baehyun Shin, Roy Jung, Alejandro Lloret, Randy Singh Atwal, Hyeongseok Lee, Jong-Min Lee, Ruedi Aebersold, Hans Hebert, Ji-Joon Song, Ihn Sik Seong

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Hypomorphic mutation of the mouse Huntington's disease gene orthologue. by Vidya Murthy, Toma Tebaldi, Toshimi Yoshida, Serkan Erdin, Teresa Calzonetti, Ravi Vijayvargia, Takshashila Tripathi, Emanuela Kerschbamer, Ihn Sik Seong, Alessandro Quattrone, Michael E Talkowski, James F Gusella, Katia Georgopoulos, Marcy E MacDonald, Marta Biagioli

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