Facts and Perspectives: Implications of tumor glycolysis on immunotherapy response in triple negative breast cancer by Ashley Schreier, Roberta Zappasodi, Roberta Zappasodi, Roberta Zappasodi, Inna Serganova, Inna Serganova, Kristy A. Brown, Sandra Demaria, Eleni Andreopoulou

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ATP-Binding Cassette Transporters Modulate Both Coelenterazine- and D-Luciferin-Based Bioluminescence Imaging by Ruimin Huang, Jelena Vider, Inna Serganova, Ronald G. Blasberg

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Epigenetic, Metabolic, and Immune Crosstalk in Germinal-Center-Derived B-Cell Lymphomas: Unveiling New Vulnerabilities for Rational Combination Therapies by Inna Serganova, Inna Serganova, Sanjukta Chakraborty, Samuel Yamshon, Yusuke Isshiki, Ryan Bucktrout, Ari Melnick, Wendy Béguelin, Roberta Zappasodi, Roberta Zappasodi, Roberta Zappasodi, Roberta Zappasodi

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Dual Reporter Gene Imaging by Jiantu Che, Mikhail Doubrovin, Inna Serganova, Ludmila Ageyeva, Pat Zanzonico, Ronald Blasberg

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HSP70-Inducible hNIS-IRES-eGFP Reporter Imaging: Response to Heat Shock by Jiantu Che, Mikhail Doubrovin, Inna Serganova, Lyudmila Ageyeva, Tatiana Beresten, Ronald Finn, Ronald Blasberg

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Real-time imaging of HIF-1alpha stabilization and degradation. by Ekaterina Moroz, Sean Carlin, Katerina Dyomina, Sean Burke, Howard T Thaler, Ronald Blasberg, Inna Serganova

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525 Investigating dynamic IDO-Kyn-AhR pathway-induced tumor immunosuppression using imaging modality to optimize AhR therapeutic intervention by Jedd D Wolchok, Taha Merghoub, Sadna Budhu, Inna Serganova, Jonathan F Khan, Mamadou A Bah

Different Strategies for Reducing Intestinal Background Radioactivity Associated with Imaging HSV1- Expression Using Established Radionucleoside Probes by Alessandro Ruggiero, Peter Brader, Inna Serganova, Pat Zanzonico, Shangde Cai, Neil S. Lipman, Hedvig Hricak, Ronald G. Blasberg

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Enhancement of PSMA-Directed CAR Adoptive Immunotherapy by PD-1/PD-L1 Blockade by Inna Serganova, Ekaterina Moroz, Ivan Cohen, Maxim Moroz, Mayuresh Mane, Juan Zurita, Larissa Shenker, Vladimir Ponomarev, Ronald Blasberg

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Genetic and Drug Inhibition of LDH-A: Effects on Murine Gliomas by Masatomo Maeda, Myat Ko, Mayuresh M. Mane, Ivan J. Cohen, Masahiro Shindo, Kiranmayi Vemuri, Inna Serganova, Ronald Blasberg

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619 Pharmacologic modulation of tumor glycolysis to improve responses to immune checkpoint blockade therapy by Taha Merghoub, Sadna Budhu, Roberta Zappasodi, Levi Mangarin, Svena Verma, Inna Serganova, Rachana Maniyar, Ronald Blasberg, Myat Ko

LDH-A—Modulation and the Variability of LDH Isoenzyme Profiles in Murine Gliomas: A Link with Metabolic and Growth Responses by Masahiro Shindo, Masatomo Maeda, Ko Myat, Mayuresh M. Mane, Ivan J. Cohen, Kiranmayi Vemuri, Avi S. Albeg, Inna Serganova, Ronald Blasberg

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Cytoplasmically Retargeted HSV1-tk/GFP Reporter Gene Mutants for Optimization of Noninvasive Molecular-Genetic Imaging by Vladimir Ponomarev, Michael Doubrovin, Inna Serganova, Tatiana Beresten, Jelena Vider, Aleksander Shavrin, Ludmila Ageyeva, Julius Balatoni, Ronald Blasberg, Juri Gelovani Tjuvajev

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Molecular Imaging of Expression of Vascular Endothelial Growth Factor a (VEGF A) in Femoral Bone Grafts Transplanted into Living Mice by Olga Strachna, Daniel Torrecilla, Marie K. Reumann, Inna Serganova, Jihye Kim, Simone Gieschler, Adele L. Boskey, Ronald G. Blasberg, Philipp Mayer-Kuckuk

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Introducing a new reporter gene, membrane-anchored Cypridina luciferase, for multiplex bioluminescence imaging by Maxim A. Moroz, Juan Zurita, Anna Moroz, Ekaterina Nikolov, Yury Likar, Konstantin Dobrenkov, Jason Lee, Larissa Shenker, Ronald Blasberg, Inna Serganova, Vladimir Ponomarev

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1444 Pharmacologic LDH inhibition redirects intratumoral glucose consumption and improves response to CTLA-4 blockade by Jedd D Wolchok, Taha Merghoub, Sadna Budhu, Roberta Zappasodi, Svena Verma, Inna Serganova, Lauren Dong, Levi Mark Mangarin, Yacine Marouf, Jonathan F Khan

Monitoring the Induction of Heat Shock Factor 1/Heat Shock Protein 70 Expression following 17-Allylamino-Demethoxygeldanamycin Treatment by Positron Emission Tomography and Optical... by Mikhail Doubrovin, Jian T. Che, Inna Serganova, Ekaterina Moroz, David B. Solit, Lyudmila Ageyeva, Tatiana Kochetkova, Nagavarakishore Pillarsetti, Ronald Finn, Neal Rosen, Ronald G. Blasberg

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Development of a New Reporter Gene System-dsRed/Xanthine Phosphoribosyltransferase-Xanthine for Molecular Imaging of Processes Behind the Intact Blood-Brain Barrier by Mikhail Doubrovin, Vladimir Ponomarev, Inna Serganova, Suren Soghomonian, Tadashi Myagawa, Tatiana Beresten, Lyudmila Ageyeva, Michel Sadelain, Jason Koutcher, Ronald G Blasberg, Juri G. Gelovani Tjuvajev

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254 CTLA-4 blockade promotes Treg glucose metabolism and reduces Treg functional stability in glycolysis-defective tumors by Yasin Senbabaoglu, Greg Delgoffe, Ping-Chih Ho, Arnab Ghosh, Svena Verma, McLane Watson, Inna Serganova, Ivan Cohen, Masatomo Maeda, Masahiro Shindo, Rachana Maniyar, Mayuresh Mane, Avigdor Leftin, Matthew Lubin, Myat Kyaw Ko, Mohsen Abu-Akeel, Ellen Ackerstaff, Jason Koutcher, Ronald Blasberg

Lactate Dehydrogenase A Depletion Alters MyC-CaP Tumor Metabolism, Microenvironment, and CAR T Cell Therapy by Mayuresh M. Mane, Ivan J. Cohen, Ellen Ackerstaff, Khalid Shalaby, Jenny N. Ijoma, Myat Ko, Masatomo Maeda, Avi S. Albeg, Kiranmayi Vemuri, Jaya Satagopan, Anna Moroz, Juan Zurita, Larissa Shenker, Masahiro Shindo, Tanner Nickles, Ekaterina Nikolov, Maxim A. Moroz, Jason A. Koutcher, Inna Serganova, Vladimir Ponomarev, Ronald G. Blasberg

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