New clinical trial designs in the era of precision medicine by Elena Garralda, Rodrigo Dienstmann, Alejandro Piris‐Giménez, Irene Braña, Jordi Rodon, Josep Tabernero

Get full text

494 Phase 1 dose escalation and dose expansion study of an agonist redirected checkpoint (ARC) fusion protein, SL-279252 (PD1-Fc-OX40L), in subjects with advanced solid tumors or l... by David Hong, Lini Pandite, Patrick Schöffski, Lilian Siu, Melissa Johnson, Louis Gonzalez, Bo Ma, Robert Hernandez, Fatima Rangwala, Vladimir Galvao, Irene Brana

Relative bioavailability of three formulations of galunisertib administered as monotherapy in patients with advanced or metastatic cancer by Ivelina Gueorguieva, Ann Cleverly, Durisala Desaiah, Analia Azaro, Joan Seoane, Irene Braña, Elisabet Sicart, Colin Miles, Michael M Lahn, Malcolm I Mitchell, Jordi Rodon

Get full text

Incidence and characteristics of adverse drug reactions in a cohort of patients treated with PD-1/PD-L1 inhibitors in real-world practice by Mònica Sabaté Gallego, Mònica Sabaté Gallego, Eulàlia Pérez Esquirol, Núria Garcia Doladé, Xavier Vidal Guitart, Xavier Vidal Guitart, Maria-Josep Carreras Soler, Anna Farriols Danés, Enriqueta Felip, Enriqueta Felip, Irene Braña, Irene Braña, Joan Carles Galceran, Joan Carles Galceran, Rafael Morales Barrera, Rafael Morales Barrera, Eva Muñoz-Couselo, Eva Muñoz-Couselo, Antònia Agustí Escasany, Antònia Agustí Escasany

Get full text

Overview of Oral Potentially Malignant Disorders: From Risk Factors to Specific Therapies by Luigi Lorini, Coro Bescós Atín, Selvam Thavaraj, Urs Müller-Richter, Margarita Alberola Ferranti, Jorge Pamias Romero, Manel Sáez Barba, Alba de Pablo García-Cuenca, Irene Braña García, Paolo Bossi, Paolo Nuciforo, Sara Simonetti

Get full text

BET inhibitor trotabresib in heavily pretreated patients with solid tumors and diffuse large B-cell lymphomas by Victor Moreno, Maria Vieito, Juan Manuel Sepulveda, Vladimir Galvao, Tatiana Hernández-Guerrero, Bernard Doger, Omar Saavedra, Carmelo Carlo-Stella, Jean-Marie Michot, Antoine Italiano, Massimo Magagnoli, Cecilia Carpio, Antonio Pinto, Rafael Sarmiento, Barbara Amoroso, Ida Aronchik, Ellen Filvaroff, Bishoy Hanna, Xin Wei, Zariana Nikolova, Irene Braña

Get full text

Digital Display Precision Predictor: the prototype of a global biomarker model to guide treatments with targeted therapy and predict progression-free survival by Vladimir Lazar, Shai Magidi, Nicolas Girard, Alexia Savignoni, Jean-François Martini, Giorgio Massimini, Catherine Bresson, Raanan Berger, Amir Onn, Jacques Raynaud, Fanny Wunder, Ioana Berindan-Neagoe, Marina Sekacheva, Irene Braña, Josep Tabernero, Enriqueta Felip, Angel Porgador, Claudia Kleinman, Gerald Batist, Benjamin Solomon, Apostolia Maria Tsimberidou, Jean-Charles Soria, Eitan Rubin, Razelle Kurzrock, Richard L. Schilsky

Get full text

A Comprehensive Biomarker Analysis of Microsatellite Unstable/Mismatch Repair Deficient Colorectal Cancer Cohort Treated with Immunotherapy by Elena Élez, Núria Mulet-Margalef, Miriam Sanso, Fiorella Ruiz-Pace, Francesco M. Mancuso, Raquel Comas, Javier Ros, Guillem Argilés, Giulia Martini, Enrique Sanz-Garcia, Iosune Baraibar, Francesc Salvà, Alba Noguerido, Jose Luis Cuadra-Urteaga, Roberta Fasani, Ariadna Garcia, Jose Jimenez, Susana Aguilar, Stefania Landolfi, Javier Hernández-Losa, Irene Braña, Paolo Nuciforo, Rodrigo Dienstmann, Josep Tabernero, Ramon Salazar, Ana Vivancos

Get full text

Antitumour activity of neratinib in patients with HER2-mutant advanced biliary tract cancers by James J. Harding, Sarina A. Piha-Paul, Ronak H. Shah, Jessica J. Murphy, James M. Cleary, Geoffrey I. Shapiro, David I. Quinn, Irene Braña, Victor Moreno, Mitesh Borad, Sherene Loi, Iben Spanggaard, Haeseong Park, James M. Ford, Mónica Arnedos, Salomon M. Stemmer, Christelle de la Fouchardiere, Christos Fountzilas, Jie Zhang, Daniel DiPrimeo, Casey Savin, S. Duygu Selcuklu, Michael F. Berger, Lisa D. Eli, Funda Meric-Bernstam, Komal Jhaveri, David B. Solit, Ghassan K. Abou-Alfa

Get full text