Isolation, culture, and immunophenotypic analysis of bone marrow HSPCs from patients with myelodysplastic syndromes by Irene Ganan-Gomez, Karen Clise-Dwyer, Simona Colla

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Accurate identification of locally aneuploid cells by incorporating cytogenetic information in single cell data analysis by Ziyi Li, Ruoxing Li, Irene Ganan-Gomez, Hussein A. Abbas, Guillermo Garcia-Manero, Wei Sun

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Overexpression of miR-125a in myelodysplastic syndrome CD34+ cells modulates NF-κB activation and enhances erythroid differentiation arrest. by Irene Gañán-Gómez, Yue Wei, Hui Yang, Sherry Pierce, Carlos Bueso-Ramos, George Calin, George Calin, María Del Carmen Boyano-Adánez, Guillermo García-Manero

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S185: TARGETING DNA2 OVERCOMES METABOLIC REPROGRAMMING IN 1Q21 MULTIPLE MYELOMA by Natthakan Thongon, Feiyang MA, Pamela Lockyer, Natalia Baran, Jintan Liu, Caleb Class, Lin Tan, Paola Storti, Valentina Marchica, Irene Ganan-Gomez, Bethany Wildeman, Vera Adema, Philip Lorenzi, Rodrigo Fonseca, Marta Chesi, Elisabeth Manasanch, Andrea Viale, Simona Colla

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Hematopoietic stem cells with granulo-monocytic differentiation state overcome venetoclax sensitivity in patients with myelodysplastic syndromes by Juan Jose Rodriguez-Sevilla, Irene Ganan-Gomez, Feiyang Ma, Kelly Chien, Monica Del Rey, Sanam Loghavi, Guillermo Montalban-Bravo, Vera Adema, Bethany Wildeman, Rashmi Kanagal-Shamanna, Alexandre Bazinet, Helen T. Chifotides, Natthakan Thongon, Xavier Calvo, Jesús María Hernández-Rivas, Maria Díez-Campelo, Guillermo Garcia-Manero, Simona Colla

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P723: CLINICAL AND MOLECULAR ASSOCIATIONS WITH OUTCOMES IN HIGHER RISK MYELODYSPLASTIC SYNDROMES TREATED WITH HYPOMETHYLATING AGENTS PLUS VENETOCLAX by Alexandre Bazinet, Sai Prasad Desikan, Ziyi LI, Sangeetha Venugopal, Samuel Urrutia, Guillermo Montalban-Bravo, Koji Sasaki, Kelly Chien, Danielle Hammond, Rashmi Kanagal-Shamanna, Bailey Mirabella, Stephany Hendrickson, Liz Romero, Simona Colla, Irene Ganan-Gomez, Juan Jose Rodriguez-Sevilla, Tapan Kadia, Courtney Dinardo, Naval Daver, Elias Jabbour, Farhad Ravandi, Hagop Kantarjian, Guillermo Garcia-Manero

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P1330: CYTOREDUCTIVE CHEMOTHERAPY COULD ACCELERATE THE LOSS OF CLONAL DIVERSITY IN HEMATOPOIETIC STEM CELLS AND PROMOTES THE CONVERGENT EVOLUTION OF THERAPY-RELATED CLONAL HEMATOPO... by Hidetaka Uryu, Koichi Saeki, Jyoti Nangalia, Michael Chapman, LI Zhao, Joanne Hsu, Carlos Bueso-Ramos, Shujuan Chen, Hui Yang, Courtney Dinardo, Naval Daver, Simona Colla, Irene Ganan-Gomez, Jianhua Zhang, Xingzhi Song, Erika Thompson, Hongli Tang, Robert Z Orlowski, Richard E. Champlin, Muzaffar H. Qazilbash, Elizabeth J. Shpall, Andrew Futreal, Guillermo Garcia-Manero, Hiroshi Haeno, Koichi Takahashi

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Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma by Natthakan Thongon, Feiyang Ma, Natalia Baran, Pamela Lockyer, Jintan Liu, Christopher Jackson, Ashley Rose, Ken Furudate, Bethany Wildeman, Matteo Marchesini, Valentina Marchica, Paola Storti, Giannalisa Todaro, Irene Ganan-Gomez, Vera Adema, Juan Jose Rodriguez-Sevilla, Yun Qing, Min Jin Ha, Rodrigo Fonseca, Caleb Stein, Caleb Class, Lin Tan, Sergio Attanasio, Guillermo Garcia-Manero, Nicola Giuliani, David Berrios Nolasco, Andrea Santoni, Claudio Cerchione, Carlos Bueso-Ramos, Marina Konopleva, Philip Lorenzi, Koichi Takahashi, Elisabet Manasanch, Gabriella Sammarelli, Rashmi Kanagal-Shamanna, Andrea Viale, Marta Chesi, Simona Colla

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