Viral Hijacking of BET Proteins Por Irene P. Chen, Melanie Ott

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SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein. Por Marius Walter, Irene P Chen, Albert Vallejo-Gracia, Ik-Jung Kim, Olga Bielska, Victor L Lam, Jennifer M Hayashi, Andrew Cruz, Samah Shah, Frank W Soveg, John D Gross, Nevan J Krogan, Keith R Jerome, Birgit Schilling, Melanie Ott, Eric Verdin

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Mild SARS-CoV-2 infection results in long-lasting microbiota instability Por Vaibhav Upadhyay, Rahul K. Suryawanshi, Preston Tasoff, Maria McCavitt-Malvido, Renuka G. Kumar, Victoria Wong Murray, Cecilia Noecker, Jordan E. Bisanz, Yulin Hswen, Connie W. Y. Ha, Bharath Sreekumar, Irene P. Chen, Susan V. Lynch, Melanie Ott, Sulggi Lee, Peter J. Turnbaugh

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SARS-CoV-2 evolution balances conflicting roles of N protein phosphorylation. Por Abdullah M Syed, Alison Ciling, Irene P Chen, Christopher R Carlson, Armin N Adly, Hannah S Martin, Taha Y Taha, Mir M Khalid, Nathan Price, Mehdi Bouhaddou, Manisha R Ummadi, Jack M Moen, Nevan J Krogan, David O Morgan, Melanie Ott, Jennifer A Doudna

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A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication in vivo. Por Taha Y Taha, Rahul K Suryawanshi, Irene P Chen, Galen J Correy, Maria McCavitt-Malvido, Patrick C O'Leary, Manasi P Jogalekar, Morgan E Diolaiti, Gabriella R Kimmerly, Chia-Lin Tsou, Ronnie Gascon, Mauricio Montano, Luis Martinez-Sobrido, Nevan J Krogan, Alan Ashworth, James S Fraser, Melanie Ott

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Rapid assembly of SARS-CoV-2 genomes reveals attenuation of the Omicron BA.1 variant through NSP6 Por Taha Y. Taha, Irene P. Chen, Jennifer M. Hayashi, Takako Tabata, Keith Walcott, Gabriella R. Kimmerly, Abdullah M. Syed, Alison Ciling, Rahul K. Suryawanshi, Hannah S. Martin, Bryan H. Bach, Chia-Lin Tsou, Mauricio Montano, Mir M. Khalid, Bharath K. Sreekumar, G. Renuka Kumar, Stacia Wyman, Jennifer A. Doudna, Melanie Ott

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NF-κB inhibitor alpha controls SARS-CoV-2 infection in ACE2-overexpressing human airway organoids Por Camille R. Simoneau, Pei-Yi Chen, Galen K. Xing, Jennifer M. Hayashi, Irene P. Chen, Mir M. Khalid, Nathan L. Meyers, Taha Y. Taha, Kristoffer E. Leon, Rahul K. Suryawanshi, Maria McCavitt-Malvido, Tal Ashuach, Krystal A. Fontaine, Lauren Rodriguez, Bastian Joehnk, Keith Walcott, Sreelakshmi Vasudevan, Xiaohui Fang, Mazharul Maishan, Shawn Schultz, Jeroen P. Roose, Michael A. Matthay, Anita Sil, Mehrdad Arjomandi, Nir Yosef, Melanie Ott

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Previous exposure to Spike-providing parental strains confers neutralizing immunity to XBB lineage and other SARS-CoV-2 recombinants in the context of vaccination Por Rahul K. Suryawanshi, Taha Y. Taha, Maria McCavitt-Malvido, Ines Silva, Mir M. Khalid, Abdullah M. Syed, Irene P. Chen, Prachi Saldhi, Bharath Sreekumar, Mauricio Montano, Kafaya Foresythe, Takako Tabata, G. Renuka Kumar, Alicia Sotomayor-Gonzalez, Venice Servellita, Amelia Gliwa, Jenny Nguyen, Noah Kojima, Teresa Arellanor, Aallyah Bussanich, Victoria Hess, Maria Shacreaw, Lauren Lopez, Matthew Brobeck, Fred Turner, Yuzhu Wang, Sydney Ghazarian, Gregg Davis, Diviana Rodriguez, Jennifer Doudna, Lee Spraggon, Charles Y. Chiu, Melanie Ott

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