The channel-activating protease CAP1/Prss8 is required for placental labyrinth maturation. by Edith Hummler, Aline Dousse, Audrey Rieder, Jean-Christophe Stehle, Isabelle Rubera, Maria-Chiara Osterheld, Friedrich Beermann, Simona Frateschi, Roch-Philippe Charles

Get full text

Renal Ischemia Tolerance Mediated by eIF5A Hypusination Inhibition Is Regulated by a Specific Modulation of the Endoplasmic Reticulum Stress by Nicolas Melis, Isabelle Rubera, Sebastien Giraud, Marc Cougnon, Christophe Duranton, Mallorie Poet, Gisèle Jarretou, Raphaël Thuillier, Laurent Counillon, Thierry Hauet, Luc Pellerin, Michel Tauc, Didier F. Pisani

Get full text

The PROPHECI trial: a phase II, double-blind, placebo-controlled, randomized clinical trial for the treatment of pseudoxanthoma elasticum with oral pyrophosphate by Laetitia Clotaire, Isabelle Rubera, Christophe Duranton, Jocelyn Gal, Emmanuel Chamorey, Hélène Humeau, Samir Yamani, Christine Chiaverini, Serge Willoteaux, Bernard Padovani, Laurie Mourozeau, Adam Mainguy, Stéphanie Baillif, Ludovic Martin, Georges Leftheriotis

Get full text

Arterial Calcifications in Patients with Liver Cirrhosis Are Linked to Hepatic Deficiency of Pyrophosphate Production Restored by Liver Transplantation by Audrey Laurain, Isabelle Rubera, Micheline Razzouk-Cadet, Stéphanie Bonnafous, Miguel Albuquerque, Valérie Paradis, Stéphanie Patouraux, Christophe Duranton, Olivier Lesaux, Georges Lefthériotis, Albert Tran, Rodolphe Anty, Philippe Gual, Antonio Iannelli, Guillaume Favre

Get full text

Inhibition of eIF5A hypusination reprogrammes metabolism and glucose handling in mouse kidney by Marc Cougnon, Romain Carcy, Nicolas Melis, Isabelle Rubera, Christophe Duranton, Karine Dumas, Jean-François Tanti, Catherine Pons, Nicolas Soubeiran, Marina Shkreli, Thierry Hauet, Luc Pellerin, Sébastien Giraud, Nicolas Blondeau, Michel Tauc, Didier F. Pisani

Get full text

Alkaline Phosphatases Account for Low Plasma Levels of Inorganic Pyrophosphate in Chronic Kidney Disease by Audrey Laurain, Audrey Laurain, Audrey Laurain, Isabelle Rubera, Christophe Duranton, Frank Rutsch, Yvonne Nitschke, Elodie Ray, Sandor Vido, Antoine Sicard, Antoine Sicard, Georges Lefthériotis, Georges Lefthériotis, Georges Lefthériotis, Guillaume Favre, Guillaume Favre, Guillaume Favre

Get full text

Activation of osmo-sensitive LRRC8 anion channels in macrophages is important for micro-crystallin joint inflammation by Twinu Wilson Chirayath, Matthias Ollivier, Mete Kayatekin, Isabelle Rubera, Chinh Nghia Pham, Jonas Friard, Nathalie Linck, Hélene Hirbec, Christèle Combes, Mylène Zarka, Frédéric Lioté, Pascal Richette, Francois Rassendren, Vincent Compan, Christophe Duranton, Hang Korng Ea

Get full text

Proximal tubular epithelial insulin receptor mediates high-fat diet–induced kidney injury by Hak Joo Lee, Meenalakshmi M. Mariappan, Luke Norton, Terry Bakewell, Denis Feliers, Sae Byeol Oh, Andrew Donati, Cherubina S. Rubannelsonkumar, Manjeri A. Venkatachalam, Stephen E. Harris, Isabelle Rubera, Michel Tauc, Goutam Ghosh Choudhury, C. Ronald Kahn, Kumar Sharma, Ralph A. DeFronzo, Balakuntalam S. Kasinath

Get full text

Mechanoprotection by Polycystins against Apoptosis Is Mediated through the Opening of Stretch-Activated K2P Channels by Rémi Peyronnet, Reza Sharif-Naeini, Joost H.A. Folgering, Malika Arhatte, Martine Jodar, Charbel El Boustany, Claire Gallian, Michel Tauc, Christophe Duranton, Isabelle Rubera, Florian Lesage, York Pei, Dorien J.M. Peters, Stefan Somlo, Frederick Sachs, Amanda Patel, Eric Honoré, Fabrice Duprat

Get full text

TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells by Malika Arhatte, Gihan S. Gunaratne, Charbel El Boustany, Ivana Y. Kuo, Céline Moro, Fabrice Duprat, Magali Plaisant, Hélène Duval, Dahui Li, Nicolas Picard, Anais Couvreux, Christophe Duranton, Isabelle Rubera, Sophie Pagnotta, Sandra Lacas-Gervais, Barbara E. Ehrlich, Jonathan S. Marchant, Aaron M. Savage, Fredericus J. M. van Eeden, Robert N. Wilkinson, Sophie Demolombe, Eric Honoré, Amanda Patel

Get full text