Abnormal functional lymphoid tolerance and enhanced myeloid exocytosis are characteristics of resting and stimulated PBMCs in cystic fibrosis patients by Clémence Gaudin, Reem Ghinnagow, Flora Lemaire, Bérengère Villeret, Isabelle Sermet-Gaudelus, Isabelle Sermet-Gaudelus, Isabelle Sermet-Gaudelus, Isabelle Sermet-Gaudelus, Jean-Michel Sallenave

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Emerging Therapeutic Approaches for Cystic Fibrosis. From Gene Editing to Personalized Medicine by Iwona Pranke, Anita Golec, Alexandre Hinzpeter, Aleksander Edelman, Isabelle Sermet-Gaudelus, Isabelle Sermet-Gaudelus, Isabelle Sermet-Gaudelus

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Achromobacter xylosoxidans airway infection is associated with lung disease severity in children with cystic fibrosis by Charlotte Marsac, Laura Berdah, Guillaume Thouvenin, Isabelle Sermet-Gaudelus, Harriet Corvol

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Characterization of nasal potential difference in cftr knockout and F508del-CFTR mice. by Emilie Lyne Saussereau, Delphine Roussel, Siradiou Diallo, Laurent Debarbieux, Aleksander Edelman, Isabelle Sermet-Gaudelus

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Plasma lipidomics reveals potential prognostic signatures within a cohort of cystic fibrosis patients by Mario Ollero, Giuseppe Astarita, Ida Chiara Guerrera, Isabelle Sermet-Gaudelus, Stéphanie Trudel, Daniele Piomelli, Aleksander Edelman

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Representation and quantification of module activity from omics data with rROMA by Matthieu Najm, Matthieu Cornet, Luca Albergante, Andrei Zinovyev, Isabelle Sermet-Gaudelus, Véronique Stoven, Laurence Calzone, Loredana Martignetti

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Putting bicarbonate on the spot: pharmacological insights for CFTR correction in the airway epithelium by Miroslaw Zajac, Miroslaw Zajac, Miroslaw Zajac, Miroslaw Zajac, Agathe Lepissier, Agathe Lepissier, Agathe Lepissier, Elise Dréano, Elise Dréano, Elise Dréano, Benoit Chevalier, Benoit Chevalier, Benoit Chevalier, Aurélie Hatton, Aurélie Hatton, Aurélie Hatton, Mairead Kelly-Aubert, Mairead Kelly-Aubert, Mairead Kelly-Aubert, Daniela Guidone, Gabrielle Planelles, Aleksander Edelman, Aleksander Edelman, Aleksander Edelman, Emmanuelle Girodon, Emmanuelle Girodon, Alexandre Hinzpeter, Alexandre Hinzpeter, Alexandre Hinzpeter, Gilles Crambert, Iwona Pranke, Iwona Pranke, Iwona Pranke, Luis. J. V. Galietta, Isabelle Sermet-Gaudelus, Isabelle Sermet-Gaudelus, Isabelle Sermet-Gaudelus, Isabelle Sermet-Gaudelus

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Myeloperoxidase Promoter Polymorphism −463G Is Associated With More Severe Clinical Expression of Cystic Fibrosis Pulmonary Disease by Wanda F. Reynolds, Isabelle Sermet-Gaudelus, Valérie Gausson, Marie-Noëlle Feuillet, Jean-Paul Bonnefont, Gérard Lenoir, Béatrice Descamps-Latscha, Véronique Witko-Sarsat

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An unexpected effect of TNF-α on F508del-CFTR maturation and function [v2; ref status: indexed, http://f1000r.es/5tv] by Sara Bitam, Iwona Pranke, Monika Hollenhorst, Nathalie Servel, Christelle Moquereau, Danielle Tondelier, Aurélie Hatton, Valérie Urbach, Isabelle Sermet-Gaudelus, Alexandre Hinzpeter, Aleksander Edelman

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An unexpected effect of TNF-α on F508del-CFTR maturation and function [v1; ref status: indexed, http://f1000r.es/5jf] by Sara Bitam, Iwona Pranke, Monika Hollenhorst, Nathalie Servel, Christelle Moquereau, Danielle Tondelier, Aurélie Hatton, Valérie Urbach, Isabelle Sermet-Gaudelus, Alexandre Hinzpeter, Aleksander Edelman

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Psychometric validation of the Cystic Fibrosis Impact Questionnaire (CF-IQ): A patient-reported outcome assessing impacts of cystic fibrosis. by Daniel Serrano, Alyssa Uzumcu, Maya Gerstein, Nicolai D Ayasse, Ella Engstrom, Frederick B Barnes, Charles Iaconangelo, Teja Thorat, Lisa J McGarry, Isabelle Sermet-Gaudelus

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Proteomic profiling of sweat in patients with cystic fibrosis provides new insights into epidermal homoeostasis by Matthieu Cornet, Thao Nguyen‐Khoa, Mairead Kelly‐Aubert, Vincent Jung, Frédérique Chedevergne, Muriel Le Bourgeois, Laura Aoust, Kévin Roger, Chiara Ida Guerrera, Isabelle Sermet‐Gaudelus

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Unsolved severe chronic rhinosinusitis elucidated by extensive CFTR genotyping by Fanny Degrugillier, Stéphanie Simon, Abdel Aissat, Natascha Remus, Chadia Mekki, Xavier Decrouy, Aurélie Hatton, Alexandre Hinzpeter, Brice Hoffmann, Isabelle Sermet‐Gaudelus, Isabelle Callebaut, Pascale Fanen, Virginie Prulière‐Escabasse

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Insights Into Patient Variability During Ivacaftor-Lumacaftor Therapy in Cystic Fibrosis by Patrick O. Hanafin, Isabelle Sermet-Gaudelus, Matthias Griese, Matthias Kappler, Helmut Ellemunter, Carsten Schwarz, Carsten Schwarz, John Wilson, John Wilson, Marsha Tan, Tony Velkov, Gauri G. Rao, Elena K. Schneider-Futschik

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Adenine base editing with engineered virus-like particles rescues the CFTR mutation G542X in patient-derived intestinal organoids by Lucia Nicosia, Iwona Pranke, Roberta V. Latorre, Joss B. Murray, Lisa Lonetti, Kader Cavusoglu-Doran, Elise Dreano, James P. Costello, Michael Carroll, Paola Melotti, Claudio Sorio, Isabelle Sermet-Gaudelus, Martina F. Scallan, Patrick T. Harrison

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Characterization of two rat models of cystic fibrosis—KO and F508del CFTR—Generated by Crispr‐Cas9 by Elise Dreano, Marc Bacchetta, Juliette Simonin, Louise Galmiche, Claire Usal, Lotfi Slimani, Jérémy Sadoine, Laurent Tesson, Ignacio Anegon, Jean‐Paul Concordet, Aurélie Hatton, Lucile Vignaud, Danielle Tondelier, Isabelle Sermet‐Gaudelus, Marc Chanson, Charles‐Henry Cottart

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Factors influencing readthrough therapy for frequent cystic fibrosis premature termination codons by Iwona Pranke, Laure Bidou, Natacha Martin, Sandra Blanchet, Aurélie Hatton, Sabrina Karri, David Cornu, Bruno Costes, Benoit Chevalier, Danielle Tondelier, Emmanuelle Girodon, Matthieu Coupet, Aleksander Edelman, Pascale Fanen, Olivier Namy, Isabelle Sermet-Gaudelus, Alexandre Hinzpeter

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Acute respiratory failure due to pulmonary exacerbation in children with cystic fibrosis admitted in a pediatric intensive care unit: outcomes and factors associated with mortality by David Drummond, Charlotte Roy, Matthieu Cornet, Julie Bucher, Véronique Boussaud, Françoise Le Pimpec-Barthes, Margaux Pontailler, Olivier Raisky, Vanessa Lopez, Claudio Barbanti, Romain Guillemain, Sylvain Renolleau, Marion Grimaud, Mehdi Oualha, Laure de Saint Blanquat, Isabelle Sermet-Gaudelus

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Correction of CFTR function in nasal epithelial cells from cystic fibrosis patients predicts improvement of respiratory function by CFTR modulators by Iwona M. Pranke, Aurélie Hatton, Juliette Simonin, Jean Philippe Jais, Françoise Le Pimpec-Barthes, Ania Carsin, Pierre Bonnette, Michael Fayon, Nathalie Stremler-Le Bel, Dominique Grenet, Matthieu Thumerel, Julie Mazenq, Valerie Urbach, Myriam Mesbahi, Emanuelle Girodon-Boulandet, Alexandre Hinzpeter, Aleksander Edelman, Isabelle Sermet-Gaudelus

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New insights into structure and function of bis-phosphinic acid derivatives and implications for CFTR modulation by Sara Bitam, Ahmad Elbahnsi, Geordie Creste, Iwona Pranke, Benoit Chevalier, Farouk Berhal, Brice Hoffmann, Nathalie Servel, Danielle Tondelier, Aurelie Hatton, Christelle Moquereau, Mélanie Faria Da Cunha, Alexandra Pastor, Agathe Lepissier, Alexandre Hinzpeter, Jean-Paul Mornon, Guillaume Prestat, Aleksander Edelman, Isabelle Callebaut, Christine Gravier-Pelletier, Isabelle Sermet-Gaudelus

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