SGLT2 Inhibition on Cardiac Mitochondrial Function: Searching for a Sweet Spot حسب Konrad Teodor Sawicki, Issam Ben‐Sahra, Elizabeth M. McNally

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The mTORC1 Signaling Network Senses Changes in Cellular Purine Nucleotide Levels حسب Gerta Hoxhaj, James Hughes-Hallett, Rebecca C. Timson, Erika Ilagan, Min Yuan, John M. Asara, Issam Ben-Sahra, Brendan D. Manning

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Acadesine kills chronic myelogenous leukemia (CML) cells through PKC-dependent induction of autophagic cell death. حسب Guillaume Robert, Issam Ben Sahra, Alexandre Puissant, Pascal Colosetti, Nathalie Belhacene, Pierre Gounon, Paul Hofman, Fréderic Bost, Jill-Patrice Cassuto, Patrick Auberger

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The hexokinase “HKDC1” interaction with the mitochondria is essential for liver cancer progression حسب Md. Wasim Khan, Alexander R. Terry, Medha Priyadarshini, Vladimir Ilievski, Zeenat Farooq, Grace Guzman, Jose Cordoba-Chacon, Issam Ben-Sahra, Barton Wicksteed, Brian T. Layden

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Longitudinal trajectories of branched chain amino acids through young adulthood and diabetes in later life حسب Konrad T. Sawicki, Hongyan Ning, Norrina B. Allen, Mercedes R. Carnethon, Amisha Wallia, James D. Otvos, Issam Ben-Sahra, Elizabeth M. McNally, Janet K. Snell-Bergeon, John T. Wilkins

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Hepatic mTORC1 signaling activates ATF4 as part of its metabolic response to feeding and insulin حسب Vanessa Byles, Yann Cormerais, Krystle Kalafut, Victor Barrera, James E. Hughes Hallett, Shannan Ho Sui, John M. Asara, Christopher M. Adams, Gerta Hoxhaj, Issam Ben-Sahra, Brendan D. Manning

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ZFP36L2 suppresses mTORc1 through a P53-dependent pathway to prevent peripartum cardiomyopathy in mice حسب Hidemichi Kouzu, Yuki Tatekoshi, Hsiang-Chun Chang, Jason S. Shapiro, Warren A. McGee, Adam De Jesus, Issam Ben-Sahra, Zoltan Arany, Jonathan Leor, Chunlei Chen, Perry J. Blackshear, Hossein Ardehali

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Therapeutic targeting of metabolic vulnerabilities in cancers with MLL3/4-COMPASS epigenetic regulator mutations حسب Zibo Zhao, Kaixiang Cao, Jun Watanabe, Cassandra N. Philips, Jacob M. Zeidner, Yukitomo Ishi, Qixuan Wang, Sarah R. Gold, Katherine Junkins, Elizabeth T. Bartom, Feng Yue, Navdeep S. Chandel, Rintaro Hashizume, Issam Ben-Sahra, Ali Shilatifard

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ASCT2 is a major contributor to serine uptake in cancer cells حسب Kelly O. Conger, Christopher Chidley, Mete Emir Ozgurses, Huiping Zhao, Yumi Kim, Svetlana E. Semina, Philippa Burns, Vipin Rawat, Lina Lietuvninkas, Ryan Sheldon, Issam Ben-Sahra, Jonna Frasor, Peter K. Sorger, Gina M. DeNicola, Jonathan L. Coloff

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Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation حسب Anthony J Covarrubias, Halil Ibrahim Aksoylar, Jiujiu Yu, Nathaniel W Snyder, Andrew J Worth, Shankar S Iyer, Jiawei Wang, Issam Ben-Sahra, Vanessa Byles, Tiffany Polynne-Stapornkul, Erika C Espinosa, Dudley Lamming, Brendan D Manning, Yijing Zhang, Ian A Blair, Tiffany Horng

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The energy disruptor metformin targets mitochondrial integrity via modification of calcium flux in cancer cells حسب Camille Loubiere, Stephan Clavel, Jerome Gilleron, Rania Harisseh, Jeremy Fauconnier, Issam Ben-Sahra, Lisa Kaminski, Kathiane Laurent, Stephanie Herkenne, Sandra Lacas-Gervais, Damien Ambrosetti, Damien Alcor, Stephane Rocchi, Mireille Cormont, Jean-François Michiels, Bernard Mari, Nathalie M. Mazure, Luca Scorrano, Alain Lacampagne, Abdallah Gharib, Jean-François Tanti, Frederic Bost

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Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathway حسب Mona Hoseini Soflaee, Rushendhiran Kesavan, Umakant Sahu, Alpaslan Tasdogan, Elodie Villa, Zied Djabari, Feng Cai, Diem H. Tran, Hieu S. Vu, Eunus S. Ali, Halie Rion, Brendan P. O’Hara, Sherwin Kelekar, James Hughes Hallett, Misty Martin, Thomas P. Mathews, Peng Gao, John M. Asara, Brendan D. Manning, Issam Ben-Sahra, Gerta Hoxhaj

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