Systemic Mastocytosis: Following the Tyrosine Kinase Inhibition Roadmap by Miguel Piris-Villaespesa, Ivan Alvarez-Twose

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Insights in Anaphylaxis and Clonal Mast Cell Disorders by David González-de-Olano, Iván Álvarez-Twose

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Cognitive, neuropsychiatric and neurological alterations in mastocytosis: A systematic review by Elena Sagües‐Sesé, Natalia García‐Casares, Ivan Álvarez‐Twose

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Diffuse cutaneous mastocytosis in a girl with M541L polymorphism in KIT gene: Response to treatment with imatinib by Aniza Giacaman, José Antonio Salinas Sanz, Mercedes Guibelalde, Iván Álvarez-Twose, Ana Martín-Santiago

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Comprehensive Analysis of Acquired Genetic Variants and Their Prognostic Impact in Systemic Mastocytosis by Oscar González-López, Javier I. Muñoz-González, Alberto Orfao, Iván Álvarez-Twose, Andrés C. García-Montero

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Diffuse Cutaneous Mastocytosis: A Current Understanding of a Rare Disease by Agnieszka Rydz, Magdalena Lange, Hanna Ługowska-Umer, Monika Sikorska, Roman J. Nowicki, Cristina Morales-Cabeza, Iván Alvarez-Twose

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Mastocytosis presenting with mast cell‐mediator release‐associated symptoms elicited by cyclo oxygenase inhibitors: prevalence, clinical, and laboratory features by Tiago Azenha Rama, José Mário Morgado, Ana Henriques, Luis Escribano, Iván Alvarez‐Twose, Laura Sanchez‐Muñoz, André Moreira, José Romão, Alberto Órfão, Almudena Matito

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Whole-Exome Sequencing Reveals Recurrent but Heterogeneous Mutational Profiles in Sporadic WHO Grade 1 Meningiomas by María González-Tablas, María González-Tablas, María González-Tablas, Carlos Prieto, Carlos Prieto, Daniel Arandia, Daniel Arandia, María Jara-Acevedo, María Jara-Acevedo, Álvaro Otero, Álvaro Otero, Daniel Pascual, Daniel Pascual, Laura Ruíz, Laura Ruíz, Iván Álvarez-Twose, Iván Álvarez-Twose, Andrés Celestino García-Montero, Andrés Celestino García-Montero, Andrés Celestino García-Montero, Andrés Celestino García-Montero, Alberto Orfao, Alberto Orfao, Alberto Orfao, Alberto Orfao, María Dolores Tabernero, María Dolores Tabernero, María Dolores Tabernero, María Dolores Tabernero

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Molecular Background, Clinical Features and Management of Pediatric Mastocytosis: Status 2021 by Magdalena Lange, Karin Hartmann, Melody C. Carter, Frank Siebenhaar, Ivan Alvarez-Twose, Inés Torrado, Knut Brockow, Joanna Renke, Ninela Irga-Jaworska, Katarzyna Plata-Nazar, Hanna Ługowska-Umer, Justyna Czarny, Anna Belloni Fortina, Francesca Caroppo, Roman J. Nowicki, Bogusław Nedoszytko, Marek Niedoszytko, Peter Valent

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<i>STAT3</i> and <i>STAT5B</i> Mutations in T/NK-Cell Chronic Lymphoproliferative Disorders of Large Granular Lymphocytes (LGL): Association with Disease Features by Noemí Muñoz-García, María Jara-Acevedo, Carolina Caldas, Paloma Bárcena, Antonio López, Noemí Puig, Miguel Alcoceba, Paula Fernández, Neus Villamor, Juan A. Flores-Montero, Karoll Gómez, María Angelina Lemes, Jose Carlos Hernández, Iván Álvarez-Twose, Jose Luis Guerra, Marcos González, Alberto Orfao, Julia Almeida

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Altered innate immune profile in blood of systemic mastocytosis patients by Alba Pérez‐Pons, María Jara‐Acevedo, Ana Henriques, Paula Navarro‐Navarro, Andrés C. García‐Montero, Iván Álvarez‐Twose, Carlos E. Pedreira, Laura Sánchez‐Muñoz, Daniela Damasceno, Carolina Caldas, Javier I. Muñoz‐González, Almudena Matito, Juan Flores‐Montero, Oscar González‐López, Ignacio Criado, Andrea Mayado, Alberto Orfao

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P1023: AVAPRITINIB IN PATIENTS WITH ADVANCED SYSTEMIC MASTOCYTOSIS (ADVSM): EFFICACY AND SAFETY ANALYSES FROM THE PHASE 2 PATHFINDER STUDY WITH 2-YEAR FOLLOW-UP by Jason Gotlib, Andreas Reiter, Deepti Radia, Michael Deininger, Tracy George, Jens Panse, Alessandro Vannucchi, Uwe Platzbecker, Ivan Alvarez-Twose, Andrzej Mital, Olivier Hermine, Ingunn Dybedal, Elizabeth O. Hexner, Lambert Span, Ruben Mesa, Prithviraj Bose, Kirsten Pettit, Stephen Oh, Hui-Min Lin, Sasa Dimitrijevic, Javier Muñoz-González, Daniel J. Deangelo

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P1017: REDUCTIONS IN INDOLENT SYSTEMIC MASTOCYTOSIS BIOMARKER BURDEN WITH AVAPRITINIB IN THE REGISTRATIONAL, DOUBLE-BLIND PLACEBO-CONTROLLED PIONEER TRIAL by Jason Gotlib, Mariana Castells, Hanneke Oude Elberink, Frank Siebenhaar, Karin Hartmann, Sigurd Broesby-Olsen, Tracy I. George, Jens Panse, Ivan Alvarez-Twose, Deepti Radia, Tsewang Tashi, Cristina Bulai Livideanu, Vito Sabato, Paul Van Daele, Sonia Cerquozzi, Ingunn Dybedal, Andreas Reiter, Celalettin Ustun, Philippe Schafhausen, Prithviraj Bose, Daniel J. Deangelo, Lindsay Rein, Pankit Vachhani, Massimo Triggiani, Mark Rafferty, Nauman Butt, Stephen Oh, Friederike Wortmann, Johanna Ungerstedt, Minakshi Taparia, Andrew T. Kuykendall, Cecilia Arana Yi, Mattias Mattsson, William Shomali, Matthew Giannetti, Ilda Bidollari, Hui-Min Lin, Robyn Scherber, Maria Roche, Cem Akin, Marcus Maurer

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Updated Diagnostic Criteria and Classification of Mast Cell Disorders: A Consensus Proposal by Peter Valent, Cem Akin, Karin Hartmann, Ivan Alvarez-Twose, Knut Brockow, Olivier Hermine, Marek Niedoszytko, Juliana Schwaab, Jonathan J. Lyons, Melody C. Carter, Hanneke Oude Elberink, Joseph H. Butterfield, Tracy I. George, Georg Greiner, Celalettin Ustun, Patrizia Bonadonna, Karl Sotlar, Gunnar Nilsson, Mohamad Jawhar, Frank Siebenhaar, Sigurd Broesby-Olsen, Selim Yavuz, Roberta Zanotti, Magdalena Lange, Boguslaw Nedoszytko, Gregor Hoermann, Mariana Castells, Deepti H. Radia, Javier I. Muñoz-Gonzalez, Wolfgang R. Sperr, Massimo Triggiani, Hanneke C. Kluin-Nelemans, Stephen J. Galli, Lawrence B. Schwartz, Andreas Reiter, Alberto Orfao, Jason Gotlib, Michel Arock, Hans-Peter Horny, Dean D. Metcalfe

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