Showing 1 - 11 results of 11 for search 'Iwan J P de Esch', query time: 0.06s Refine Results
  1. 1
    Structure Activity Relationship of N-Substituted Phenyldihydropyrazolones Against Trypanosoma cruzi Amastigotes

    Structure Activity Relationship of N-Substituted Phenyldihydropyrazolones Against Trypanosoma cruzi Amastigotes by Maarten Sijm, Louis Maes, Iwan J. P. de Esch, Guy Caljon, Geert Jan Sterk, Rob Leurs

    Published 2021-04-01
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  2. 2
    Exploring the Effect of Cyclization of Histamine H1 Receptor Antagonists on Ligand Binding Kinetics

    Exploring the Effect of Cyclization of Histamine H1 Receptor Antagonists on Ligand Binding Kinetics by Zhiyong Wang, Reggie Bosma, Sebastiaan Kuhne, Jelle van den Bor, Wrej Garabitian, Henry F. Vischer, Maikel Wijtmans, Rob Leurs, Iwan J.P. de Esch

    Published 2021-05-01
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  3. 3
    Bromo-Cyclobutenaminones as New Covalent UDP-<i>N</i>-Acetylglucosamine Enolpyruvyl Transferase (MurA) Inhibitors

    Bromo-Cyclobutenaminones as New Covalent UDP-<i>N</i>-Acetylglucosamine Enolpyruvyl Transferase (MurA) Inhibitors by David J. Hamilton, Péter Ábrányi-Balogh, Aaron Keeley, László Petri, Martina Hrast, Tímea Imre, Maikel Wijtmans, Stanislav Gobec, Iwan J. P. de Esch, György Miklós Keserű

    Published 2020-11-01
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  4. 4
    Green Drug Discovery: Novel Fragment Space from the Biomass-Derived Molecule Dihydrolevoglucosenone (Cyrene<sup>TM</sup>)

    Green Drug Discovery: Novel Fragment Space from the Biomass-Derived Molecule Dihydrolevoglucosenone (Cyrene<sup>TM</sup>) by Tom Dekker, Jaap W. Harteveld, Gábor Wágner, Max C. M. de Vries, Hans Custers, Andrea C. van de Stolpe, Iwan J. P. de Esch, Maikel Wijtmans

    Published 2023-02-01
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  5. 5
    Predicting the target landscape of kinase inhibitors using 3D convolutional neural networks.

    Predicting the target landscape of kinase inhibitors using 3D convolutional neural networks. by Georgi K Kanev, Yaran Zhang, Albert J Kooistra, Andreas Bender, Rob Leurs, David Bailey, Thomas Würdinger, Chris de Graaf, Iwan J P de Esch, Bart A Westerman

    Published 2023-09-01
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  6. 6
    In Silico Veritas: The Pitfalls and Challenges of Predicting GPCR-Ligand Interactions

    In Silico Veritas: The Pitfalls and Challenges of Predicting GPCR-Ligand Interactions by Sander B. Nabuurs, Jan P.G. Klomp, Rob Leurs, Jacob De Vlieg, Iwan J.P. De Esch, Bas Vroling, Marijn P.A. Sanders, Luc Roumen, Chris De Graaf

    Published 2011-09-01
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  7. 7
    Vanishing white matter: Eukaryotic initiation factor 2B model and the impact of missense mutations

    Vanishing white matter: Eukaryotic initiation factor 2B model and the impact of missense mutations by Inna Slynko, Stephanie Nguyen, Eline M. C. Hamilton, Lisanne E. Wisse, Iwan J. P. deEsch, Chris deGraaf, John B. Bruning, Christopher G. Proud, Truus E. M. Abbink, Marjo S. van derKnaap

    Published 2021-03-01
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  8. 8
    Discovery of Diaryl Ether Substituted Tetrahydrophthalazinones as TbrPDEB1 Inhibitors Following Structure-Based Virtual Screening

    Discovery of Diaryl Ether Substituted Tetrahydrophthalazinones as TbrPDEB1 Inhibitors Following Structure-Based Virtual Screening by Erik de Heuvel, Albert J. Kooistra, Ewald Edink, Sjors van Klaveren, Jeffrey Stuijt, Tiffany van der Meer, Payman Sadek, Dorien Mabille, Guy Caljon, Louis Maes, Marco Siderius, Iwan J. P. de Esch, Geert Jan Sterk, Rob Leurs

    Published 2021-01-01
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  9. 9
    Phenyldihydropyrazolones as Novel Lead Compounds Against Trypanosoma cruzi

    Phenyldihydropyrazolones as Novel Lead Compounds Against Trypanosoma cruzi by Maarten Sijm, Julianna Siciliano de Araújo, Stefan Kunz, Susanne Schroeder, Ewald Edink, Kristina M. Orrling, An Matheeussen, Tiffany van de Meer, Payman Sadek, Hans Custers, Ignacio Cotillo, Julio J. Martin, Marco Siderius, Louis Maes, David G. Brown, Maria de Nazaré Correia Soeiro, GeertJan Sterk, Iwan J.P. de Esch, Rob Leurs

    Published 2019-04-01
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  10. 10
    To Target or Not to Target <i>Schistosoma mansoni</i> Cyclic Nucleotide Phosphodiesterase 4A?

    To Target or Not to Target <i>Schistosoma mansoni</i> Cyclic Nucleotide Phosphodiesterase 4A? by Yang Zheng, Susanne Schroeder, Georgi K. Kanev, Sanaa S. Botros, Samia William, Abdel-Nasser A. Sabra, Louis Maes, Guy Caljon, Carmen Gil, Ana Martinez, Irene G. Salado, Koen Augustyns, Ewald Edink, Maarten Sijm, Erik de Heuvel, Iwan J. P. de Esch, Tiffany van der Meer, Marco Siderius, Geert Jan Sterk, David Brown, Rob Leurs

    Published 2023-04-01
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  11. 11
    Screening of a PDE-focused library identifies imidazoles with in vitro and in vivo antischistosomal activity

    Screening of a PDE-focused library identifies imidazoles with in vitro and in vivo antischistosomal activity by Sanaa S. Botros, Samia William, Abdel-Nasser A. Sabra, Naglaa M. El-Lakkany, Sayed H. Seif el-Din, Alfonso García-Rubia, Victor Sebastián-Pérez, Antoni R. Blaazer, Erik de Heuvel, Maarten Sijm, Yang Zheng, Irene G. Salado, Jane C. Munday, Louis Maes, Iwan J.P. de Esch, Geert J. Sterk, Koen Augustyns, Rob Leurs, Carmen Gil, Harry P. De Koning

    Published 2019-04-01
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