Power out chronic lymphocytic leukemia: unplugging OXPHOS/mTOR pathways to overcome venetoclax resistance by Elodie Viry, Jerome Paggetti

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Editorial: New Insights into the Complexity of Tumor Immunology in B-cell Malignancies: Tumor Immunology and Immunotherapy by Martina Seiffert, Etienne Moussay, Jérôme Paggetti

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Hematological Malignancy-Derived Small Extracellular Vesicles and Tumor Microenvironment: The Art of Turning Foes into Friends by Ernesto Gargiulo, Jerome Paggetti, Etienne Moussay

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Natural killer cells and bone marrow mesenchymal stem cells: A dangerous liaison in multiple myeloma by Iria Fernandez Botana, Etienne Moussay, Jérôme Paggetti

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Small extracellular vesicles: multi-faceted tools for leukemia immune evasion in vivo by Ernesto Gargiulo, Elodie Viry, Etienne Moussay, Jerome Paggetti

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Targeting mRNA translation aberrations: A novel approach for therapy in chronic lymphocytic leukemia by Vanessa Klapp, Jerome Paggetti, Anne Largeot, Etienne Moussay

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Interleukin-27 tackles immunosuppression in chronic lymphocytic leukemia by Iria Fernandez Botana, Giulia Pagano, Etienne Moussay, Jerome Paggetti

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The B-side of Cancer Immunity: The Underrated Tune by Anne Largeot, Giulia Pagano, Susanne Gonder, Etienne Moussay, Jerome Paggetti

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Protocol for isolating leukemia-derived extracellular vesicles from the spleen of preclinical models of leukemia using ultracentrifugation by Ernesto Gargiulo, Pablo Elias Morande, Maxmilan Jeyakumar, Lucie Rospape, Jérôme Paggetti, Etienne Moussay

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Editorial: Metabolic barriers in cancer and cancer therapy by Sascha Kahlfuss, Sascha Kahlfuss, Sascha Kahlfuss, Sascha Kahlfuss, Jérôme Paggetti, Martin Böttcher, Martin Böttcher

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The prohibitin-binding compound fluorizoline induces apoptosis in chronic lymphocytic leukemia cells ex vivo but fails to prevent leukemia development in a murine model by Marina Wierz, Sandrine Pierson, Nora Chouha, Laurent Désaubry, Jean-Hugues François, Guy Berchem, Jerome Paggetti, Etienne Moussay

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P598: DISRUPTION IN ONE-CARBON METABOLISM THROUGH MTHFD1 INHIBITION AS NOVEL THERAPEUTIC STRATEGY IN CHRONIC LYMPHOCYTIC LEUKEMIA by Elodie Viry, Chloé Duculty, Nicole Kiweler, Coralie Pulido, Anais Oudin, Ana Slipicevic, Martin Henriksson, Johannes Meise, Thomas Helleday, Etienne Moussay, Jérôme Paggetti

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The protective role of the microenvironment in hairy cell leukemia treatment: Facts and perspectives by Ernesto Gargiulo, Ernesto Gargiulo, Ernesto Gargiulo, Mirta Giordano, Carsten U. Niemann, Carsten U. Niemann, Etienne Moussay, Jérôme Paggetti, Pablo Elías Morande, Pablo Elías Morande

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Hypoxic tumor-derived microvesicles negatively regulate NK cell function by a mechanism involving TGF-β and miR23a transfer by Guy Berchem, Muhammad Zaeem Noman, Manon Bosseler, Jerome Paggetti, Sonia Baconnais, Eric Le cam, Arash Nanbakhsh, Etienne Moussay, Fathia Mami-Chouaib, Bassam Janji, Salem Chouaib

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The small inhibitor WM-1119 effectively targets KAT6A-rearranged AML, but not KMT2A-rearranged AML, despite shared KAT6 genetic dependency by Mathew Sheridan, Muhammad Ahmad Maqbool, Anne Largeot, Liam Clayfield, Jingru Xu, Natalia Moncaut, Robert Sellers, Jessica Whittle, Jerome Paggetti, Mudassar Iqbal, Romain Aucagne, Laurent Delva, Syed Murtuza Baker, Michael Lie-a-Ling, Valerie Kouskoff, Georges Lacaud

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Interleukin-27 potentiates CD8+ T-cell-mediated antitumor immunity in chronic lymphocytic leukemia by Giulia Pagano, Iria Fernandez Botana, Marina Wierz, Philipp M. Roessner, Nikolaos Ioannou, Xiangda Zhou, Gheed Al-Hity, Coralie Borne, Ernesto Gargiulo, Susanne Gonder, Bin Qu, Basile Stamatopoulos, Alan G. Ramsay, Martina Seiffert, Anne Largeot, Etienne Moussay, Jerome Paggetti

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PKM2 diverts glycolytic flux in dependence on mitochondrial one-carbon cycle by Mohaned Benzarti, Laura Neises, Anais Oudin, Christina Krötz, Elodie Viry, Ernesto Gargiulo, Coralie Pulido, Maryse Schmoetten, Vitaly Pozdeev, Nadia I. Lorenz, Michael W. Ronellenfitsch, David Sumpton, Marc Warmoes, Christian Jaeger, Antoine Lesur, Björn Becker, Etienne Moussay, Jerome Paggetti, Simone P. Niclou, Elisabeth Letellier, Johannes Meiser

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S141: INHIBITION OF MYC TRANSLATION THROUGH TARGETING OF THE NEWLY IDENTIFIED PHB-EIF4F COMPLEX AS THERAPEUTIC STRATEGY INCHRONIC LYMPHOCYTIC LEUKEMIA (CLL) by Anne Largeot, Vanessa Klapp, Elodie Viry, Susanne Gonder, Iria Fernandez Botana, Arnaud Blomme, Mohaned Benzarti, Sandrine Pierson, Chloé Duculty, Petra Marttila, Marina Wierz, Ernesto Gargiulo, Giulia Pagano, Ning An, Najla El Hachem, Daniel Perez Hernandez, Supriya Chakraborty, Loic Ysebaert, Jean-Hugues François, Susan Cortez, Guy Berchem, Dimitar G Efremov, Gunnar Dittmar, Martyna Szpakowska, Andy Chevigne, Petr V. Nazarov, Thomas Helleday, Pierre Close, Johannes Meiser, Basile Stamatopoulos, Laurent Désaubry, Jérôme Paggetti, Etienne Moussay

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