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Analyzing the ER stress response in ALS patient derived motor neurons identifies druggable neuroprotective targets por Michelle E. Watts, Michelle E. Watts, Richard M. Giadone, Richard M. Giadone, Alban Ordureau, Kristina M. Holton, Kristina M. Holton, J. Wade Harper, Lee L. Rubin, Lee L. Rubin
Publicado em 2024-01-01
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NCOA4 maintains murine erythropoiesis via cell autonomous and non-autonomous mechanisms por Naiara Santana-Codina, Sebastian Gableske, Maria Quiles del Rey, Beata Małachowska, Mark P. Jedrychowski, Douglas E. Biancur, Paul J. Schmidt, Mark D. Fleming, Wojciech Fendler, J. Wade Harper, Alec C. Kimmelman, Joseph D. Mancias
Publicado em 2019-07-01
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Structural basis for C-degron selectivity across KLHDCX family E3 ubiquitin ligases por Daniel C. Scott, Sagar Chittori, Nicholas Purser, Moeko T. King, Samuel A. Maiwald, Kelly Churion, Amanda Nourse, Chan Lee, Joao A. Paulo, Darcie J. Miller, Stephen J. Elledge, J. Wade Harper, Gary Kleiger, Brenda A. Schulman
Publicado em 2024-11-01
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Principles of paralog-specific targeted protein degradation engaging the C-degron E3 KLHDC2 por Daniel C. Scott, Suresh Dharuman, Elizabeth Griffith, Sergio C. Chai, Jarrid Ronnebaum, Moeko T. King, Rajendra Tangallapally, Chan Lee, Clifford T. Gee, Lei Yang, Yong Li, Victoria C. Loudon, Ha Won Lee, Jason Ochoada, Darcie J. Miller, Thilina Jayasinghe, Joao A. Paulo, Stephen J. Elledge, J. Wade Harper, Taosheng Chen, Richard E. Lee, Brenda A. Schulman
Publicado em 2024-10-01
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