Nicotinamide-N-methyltransferase controls behavior, neurodegeneration and lifespan by regulating neuronal autophagy. by Kathrin Schmeisser, J Alex Parker

Get full text

Heritable transmission of stress resistance by high dietary glucose in Caenorhabditis elegans. by Arnaud Tauffenberger, J Alex Parker

Get full text

Pleiotropic Effects of mTOR and Autophagy During Development and Aging by Kathrin Schmeisser, J. Alex Parker

Get full text

Worming forward: amyotrophic lateral sclerosis toxicity mechanisms and genetic interactions in Caenorhabditis elegans by Martine eTherrien, J Alex Parker

Get full text

Rescue of ATXN3 neuronal toxicity in Caenorhabditis elegans by chemical modification of endoplasmic reticulum stress by Yasmin Fardghassemi, Arnaud Tauffenberger, Sarah Gosselin, J. Alex Parker

Get full text

Deletion of C9ORF72 results in motor neuron degeneration and stress sensitivity in C. elegans. by Martine Therrien, Guy A Rouleau, Patrick A Dion, J Alex Parker

Get full text

Mutant TDP-43 and FUS cause age-dependent paralysis and neurodegeneration in C. elegans. by Alexandra Vaccaro, Arnaud Tauffenberger, Dina Aggad, Guy Rouleau, Pierre Drapeau, J Alex Parker

Get full text

Cross-talk between canonical Wnt signaling and the sirtuin-FoxO longevity pathway to protect against muscular pathology induced by mutant PABPN1 expression in C. elegans by Matthieu Y. Pasco, Hélène Catoire, J. Alex Parker, Bernard Brais, Guy A. Rouleau, Christian Néri

Get full text

Modulating the endoplasmic reticulum stress response attenuates neurodegeneration in a Caenorhabditis elegans model of spinal muscular atrophy by James J. Doyle, Celine Vrancx, Claudia Maios, Audrey Labarre, Shunmoogum A. Patten, J. Alex Parker

Get full text

TDP-1/TDP-43 regulates stress signaling and age-dependent proteotoxicity in Caenorhabditis elegans. by Alexandra Vaccaro, Arnaud Tauffenberger, Peter E A Ash, Yari Carlomagno, Leonard Petrucelli, J Alex Parker

Get full text

Fishing for causes and cures of motor neuron disorders by Shunmoogum A. Patten, Gary A. B. Armstrong, Alexandra Lissouba, Edor Kabashi, J. Alex Parker, Pierre Drapeau

Get full text

Methylene blue protects against TDP-43 and FUS neuronal toxicity in C. elegans and D. rerio. by Alexandra Vaccaro, Shunmoogum A Patten, Sorana Ciura, Claudia Maios, Martine Therrien, Pierre Drapeau, Edor Kabashi, J Alex Parker

Get full text

Fatty acids derived from the probiotic Lacticaseibacillus rhamnosus HA-114 suppress age-dependent neurodegeneration by Audrey Labarre, Ericka Guitard, Gilles Tossing, Anik Forest, Eric Bareke, Marjorie Labrecque, Martine Tétreault, Matthieu Ruiz, J. Alex Parker

Get full text

The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease by Francesca Farina, Emmanuel Lambert, Lucie Commeau, François-Xavier Lejeune, Nathalie Roudier, Cosima Fonte, J. Alex Parker, Jacques Boddaert, Marc Verny, Etienne-Emile Baulieu, Christian Neri

Get full text

Phosphoglycolate phosphatase homologs act as glycerol-3-phosphate phosphatase to control stress and healthspan in C. elegans by Elite Possik, Clémence Schmitt, Anfal Al-Mass, Ying Bai, Laurence Côté, Johanne Morin, Heidi Erb, Abel Oppong, Wahab Kahloan, J. Alex Parker, S. R. Murthy Madiraju, Marc Prentki

Get full text

The Wnt receptor Ryk reduces neuronal and cell survival capacity by repressing FOXO activity during the early phases of mutant huntingtin pathogenicity. by Cendrine Tourette, Francesca Farina, Rafael P Vazquez-Manrique, Anne-Marie Orfila, Jessica Voisin, Sonia Hernandez, Nicolas Offner, J Alex Parker, Sophie Menet, Jinho Kim, Jungmok Lyu, Si Ho Choi, Kerry Cormier, Christina K Edgerly, Olivia L Bordiuk, Karen Smith, Anne Louise, Michael Halford, Steven Stacker, Jean-Philippe Vert, Robert J Ferrante, Wange Lu, Christian Neri

Get full text